Deep brain stimulation of the posterior hypothalamus activates the histaminergic system to exert antiepileptic effect in rat pentylenetetrazol model

2007 ◽  
Vol 205 (1) ◽  
pp. 132-144 ◽  
Author(s):  
N NISHIDA ◽  
Z HUANG ◽  
N MIKUNI ◽  
Y MIURA ◽  
Y URADE ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Posterior Hypothalamus ◽  
Histaminergic System ◽  
Deep Brain ◽  
Stimulation Of

scholarly journals 200 The Treatment of Chronic Cluster Headache With Deep Brain Stimulation of the Posterior Hypothalamus

Neurosurgery ◽  
2018 ◽  
Vol 65 (CN_suppl_1) ◽  
pp. 115-115
Author(s):  
Nilson N. Mendes Neto ◽  
Jessika Thais da Silva Maia ◽  
Juliano Jose da Silva ◽  
Sergio Adrian Fernandes Dantas ◽  
Marcelo Rodrigues Zacarkim ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Cluster Headache ◽  
Brain Stimulation ◽  
Chronic Cluster Headache ◽  
Posterior Hypothalamus ◽  
Deep Brain ◽  
Stimulation Of

Deep Brain Stimulation of the Posterior Hypothalamus in Chronic Cluster Headache

2009 ◽  
pp. 509-513
Author(s):  
Angelo Franzini ◽  
Giuseppe Messina ◽  
Massimo Leone ◽  
Gennaro Bussone ◽  
Carlo Marras ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Cluster Headache ◽  
Brain Stimulation ◽  
Chronic Cluster Headache ◽  
Posterior Hypothalamus ◽  
Deep Brain ◽  
Stimulation Of

Deep brain stimulation modulates hypothalamic-brainstem fibers in cluster headache: case report

2020 ◽  
Vol 132 (3) ◽  
pp. 717-720 ◽  
Author(s):  
Sérgio A. F. Dantas ◽  
Eduardo J. L. Alho ◽  
Juliano J. da Silva ◽  
Nilson N. Mendes Neto ◽  
Erich Talamoni Fonoff ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Cluster Headache ◽  
Brain Stimulation ◽  
Clinical Effects ◽  
Chronic Stimulation ◽  
Mammillary Bodies ◽  
Fiber Tracts ◽  
White Matter Region ◽  
Deep Brain ◽  
Stimulation Of

Hypothalamic deep brain stimulation (DBS) has been used for more than a decade to treat cluster headache (CH) but its mechanisms remain poorly understood. The authors have successfully treated a patient with CH using hypothalamic DBS and found that the contact used for chronic stimulation was located in a white matter region posterior to the mammillary bodies. Fiber tracts crossing that region were the medial forebrain bundle and those interconnecting the hypothalamus and brainstem, including the dorsal longitudinal fasciculus. Because the stimulation of axons is an important mechanism of DBS, some of its clinical effects in CH may be related to the stimulation of fibers interconnecting the hypothalamus and brainstem.

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