scholarly journals The WRN helicase: resolving a new target in microsatellite unstable cancers

2021 ◽  
Vol 71 ◽  
pp. 34-38
Author(s):  
Niek van Wietmarschen ◽  
William J Nathan ◽  
André Nussenzweig
Keyword(s):  
Wrn Helicase

scholarly journals p53 Modulates RPA-Dependent and RPA-Independent WRN Helicase Activity

2005 ◽  
Vol 65 (4) ◽  
pp. 1223-1233 ◽  
Author(s):  
Joshua A. Sommers ◽  
Sudha Sharma ◽  
Kevin M. Doherty ◽  
Parimal Karmakar ◽  
Qin Yang ◽  
...  
Keyword(s):  
Helicase Activity ◽  
Wrn Helicase

Abstract LB-048: WRN helicase is a synthetic lethal target in microsatellite unstable cancers

2019 ◽  
Author(s):  
Edmond M. Chan ◽  
Tsukasa Shibue ◽  
James McFarland ◽  
Benjamin Gaeta ◽  
Francisca Vazquez ◽  
...  
Keyword(s):  
Synthetic Lethal ◽  
Wrn Helicase

scholarly journals Functional and Physical Interaction between WRN Helicase and Human Replication Protein A

1999 ◽  
Vol 274 (26) ◽  
pp. 18341-18350 ◽  
Author(s):  
Robert M. Brosh ◽  
David K. Orren ◽  
Jan O. Nehlin ◽  
Peter H. Ravn ◽  
Mark K. Kenny ◽  
...  
Keyword(s):  
Protein A ◽  
Replication Protein A ◽  
Replication Protein ◽  
Physical Interaction ◽  
Wrn Helicase

scholarly journals Delineation of WRN helicase function with EXO1 in the replicational stress response

DNA Repair ◽  
2010 ◽  
Vol 9 (7) ◽  
pp. 765-776 ◽  
Author(s):  
Monika Aggarwal ◽  
Joshua A. Sommers ◽  
Christa Morris ◽  
Robert M. Brosh Jr.
Keyword(s):  
Stress Response ◽  
Wrn Helicase

scholarly journals Single-molecule studies reveal reciprocating of WRN helicase core along ssDNA during DNA unwinding

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Wen-Qiang Wu ◽  
Xi-Miao Hou ◽  
Bo Zhang ◽  
Philippe Fossé ◽  
Brigitte René ◽  
...  
Keyword(s):  
Single Molecule ◽  
Dna Unwinding ◽  
Single Molecule Studies ◽  
Wrn Helicase

scholarly journals Targeting an Achilles’ heel of cancer with a WRN helicase inhibitor

Cell Cycle ◽  
2013 ◽  
Vol 12 (20) ◽  
pp. 3329-3335 ◽  
Author(s):  
Monika Aggarwal ◽  
Taraswi Banerjee ◽  
Joshua A Sommers ◽  
Robert M Brosh, Jr
Keyword(s):  
Wrn Helicase
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