Preventing nonsteroidal anti-inflammatory drug–induced small-bowel injury: the saga continues

2009 ◽  
Vol 69 (7) ◽  
pp. 1347-1349
Author(s):  
Rashmi Tadiparthi ◽  
Naurang M. Agrawal
Keyword(s):  
Small Bowel ◽  
Bowel Injury ◽  
Small Bowel Injury ◽  
Drug Induced ◽  
Inflammatory Drug ◽  
Anti Inflammatory

Anti-tumour necrosis factor agents reduce non-steroidal anti-inflammatory drug-induced small bowel injury in rheumatoid arthritis patients

Gut ◽  
2013 ◽  
Vol 63 (3) ◽  
pp. 409-414 ◽  
Author(s):  
Toshio Watanabe ◽  
Tetsuya Tanigawa ◽  
Masatsugu Shiba ◽  
Yuji Nadatani ◽  
Yasuaki Nagami ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Small Bowel ◽  
Tumour Necrosis Factor ◽  
Tumour Necrosis ◽  
Bowel Injury ◽  
Small Bowel Injury ◽  
Drug Induced ◽  
Inflammatory Drug ◽  
Anti Inflammatory ◽  
Necrosis Factor

scholarly journals Non-steroidal anti-inflammatory drug-induced diaphragm disease: an uncommon cause of small bowel obstruction

2016 ◽  
Vol 98 (8) ◽  
pp. e189-e191 ◽  
Author(s):  
MME Coolsen ◽  
SJ Leedham ◽  
RJ Guy
Keyword(s):  
Small Bowel ◽  
Small Bowel Obstruction ◽  
Bowel Obstruction ◽  
Small Bowel Resection ◽  
Drug Induced ◽  
Inflammatory Drug ◽  
Diaphragm Disease ◽  
Anti Inflammatory ◽  
Diagnostic Work ◽  
Work Up

Surgeons frequently deal with small bowel obstruction. However, small bowel obstruction caused by non-steroidal anti-inflammatory drug (NSAID)-induced diaphragm disease is very rare. The diagnosis is challenging, as symptoms are often non-specific and radiological studies remain inconclusive. We present a case of a 63-year-old man who, after an extensive diagnostic work-up and small bowel resection for obstructive symptoms, was finally diagnosed with NSAID-induced diaphragm disease as confirmed by histology. An unusual aspect of this case is that the patient stopped using NSAIDs after he was diagnosed with a gastric ulcer 2–years previously. This suggests that NSAID-induced diaphragms of the small bowel take some time to develop and underlines the importance of careful history taking.

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