Su1664 Development of a New Algorithm for an Automated Detection and Characterization of Bile Ducts From ERCP Images: a Pilot Study in Patients With Primary Sclerosing Cholangitis and Healthy Controls

2014 ◽  
Vol 79 (5) ◽  
pp. AB358-AB359
Author(s):  
Carsten Schmidt ◽  
Christian LautenschläGER ◽  
Janin LautenschläGER ◽  
Herbert SüSse ◽  
Joachim Denzler ◽  
...  
Keyword(s):  
Pilot Study ◽  
Primary Sclerosing Cholangitis ◽  
Sclerosing Cholangitis ◽  
Bile Ducts ◽  
Automated Detection ◽  
Healthy Controls

scholarly journals Characterization of animal models for primary sclerosing cholangitis (PSC)

2014 ◽  
Vol 60 (6) ◽  
pp. 1290-1303 ◽  
Author(s):  
Peter Fickert ◽  
Marion J. Pollheimer ◽  
Ulrich Beuers ◽  
Carolin Lackner ◽  
Gideon Hirschfield ◽  
...  
Keyword(s):  
Animal Models ◽  
Primary Sclerosing Cholangitis ◽  
Sclerosing Cholangitis

scholarly journals Magnetic Resonance Imaging in Primary Sclerosing Cholangitis

2021 ◽  
Vol 3 (2) ◽  
pp. 20-24
Author(s):  
Aldona Wybraniec-Zaręba ◽  
Julia Tuchalska-Czuroń ◽  
Gabriela Półtorak-Szymczak ◽  
Mariusz Furmanek ◽  
Jerzy Walecki ◽  
...  
Keyword(s):  
Bile Duct ◽  
Magnetic Resonance ◽  
Primary Sclerosing Cholangitis ◽  
Sclerosing Cholangitis ◽  
Bile Ducts ◽  
Extrahepatic Bile Duct ◽  
Magnetic Resonance Cholangiopancreatography ◽  
Left Liver Lobe ◽  
Bile Duct Stenosis ◽  
Mri Features

Primary sclerosing cholangitis (PSC) is a chronic liver disease in which there are inflammation and scarring of the bile ducts leading to fibrosis, destruction and narrowing of the bile ducts, resulting in cholestasis. In the long run, PSC can cause liver cirrhosis and failure. In clinical practice, the diagnosis of PSC is generally based on blood tests and imaging studies (currently preferably magnetic resonance cholangiopancreatography). To make a diagnosis of PSC it is necessary to exclude secondary causes of sclerosing cholangitis. The most common MRI features of PSC concerning bile ducts are: bile duct dilatation, beading, extrahepatic bile duct stenosis, wall enhancement and thickening. The most common MRI features of PSC concerning hepatic parenchyma are: rounded shape of the liver caused by hypertrophy of caudate lobe and left liver lobe, atrophy of the right lobe, enlargement of portal and/or portacaval lymph nodes, peripheral parenchymal inflammation, wedge-shaped confluent fibrosis, heterogeneity of the liver parenchyma, periportal oedema, cirrhosis with indirect signs of portal hypertension such as splenomegaly, ascites and collateral vasculature.

scholarly journals Successful Treatment of Recurrent Primary Sclerosing Cholangitis after Orthotopic Liver Transplantation with Oral Vancomycin

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Yinka K. Davies ◽  
Cynthia J. Tsay ◽  
Dario V. Caccamo ◽  
Kathleen M. Cox ◽  
Ricardo O. Castillo ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Liver Transplantation ◽  
Primary Sclerosing Cholangitis ◽  
Orthotopic Liver Transplantation ◽  
Successful Treatment ◽  
Sclerosing Cholangitis ◽  
Bile Ducts ◽  
Biliary Tree ◽  
Oral Vancomycin ◽  
Inflammatory Bowel

Primary sclerosing cholangitis (PSC) is a progressive, cholestatic disease of the liver that is marked by inflammation of the bile ducts and damage to the hepatic biliary tree. Approximately 60–70% of patients also have inflammatory bowel disease and progression of PSC can lead to ulcerative colitis and cirrhosis of the liver. Due to limited understanding of the etiology and mechanism of PSC, the only existing treatment option is orthotopic liver transplantation (OLT); however, recurrence of PSC, after OLT is estimated to be between 5% and 35%. We discuss the successful treatment of a pediatric patient, with recurrent PSC, after OLT with oral Vancomycin.

Beaded bile ducts in primary sclerosing cholangitis

2019 ◽  
Vol 44 (3) ◽  
pp. 1195-1196 ◽  
Author(s):  
Dario Giambelluca ◽  
Claudio Leto ◽  
Francesco D’Arpa ◽  
Massimo Midiri ◽  
Giuseppe Salvaggio
Keyword(s):  
Primary Sclerosing Cholangitis ◽  
Sclerosing Cholangitis ◽  
Bile Ducts

scholarly journals Efficacy and safety of curcumin in primary sclerosing cholangitis: an open label pilot study

2019 ◽  
Vol 54 (5) ◽  
pp. 633-639 ◽  
Author(s):  
John E. Eaton ◽  
Kevin M. Nelson ◽  
Andrea A. Gossard ◽  
Elizabeth J. Carey ◽  
James H Tabibian ◽  
...  
Keyword(s):  
Pilot Study ◽  
Primary Sclerosing Cholangitis ◽  
Sclerosing Cholangitis ◽  
Efficacy And Safety ◽  
Open Label
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