Influence of Haemophilus influenzae β-lactamase production and/or ftsI gene mutations on in vitro activity of and susceptibility rates to aminopenicillins and second- and third-generation cephalosporins

2007 ◽  
Vol 30 (2) ◽  
pp. 190-192 ◽  
Author(s):  
J. García-de-Lomas ◽  
M. Lerma ◽  
L. Cebrián ◽  
J.L. Juan-Bañón ◽  
P. Coronel ◽  
...  
Keyword(s):  
Haemophilus Influenzae ◽  
Gene Mutations ◽  
Vitro Activity ◽  
Third Generation ◽  
In Vitro Activity ◽  
Third Generation Cephalosporins

scholarly journals In Vitro Activity of Tebipenem, a New Oral Carbapenem Antibiotic, against β-Lactamase-Nonproducing, Ampicillin-Resistant Haemophilus influenzae

2010 ◽  
Vol 54 (9) ◽  
pp. 3970-3973 ◽  
Author(s):  
Kozue Kishii ◽  
Naoko Chiba ◽  
Miyuki Morozumi ◽  
Akiko Ono ◽  
Takashi Ida ◽  
...  
Keyword(s):  
Haemophilus Influenzae ◽  
Bactericidal Activity ◽  
Gene Mutations ◽  
Vitro Activity ◽  
In Vitro Activity ◽  
Oral Antibiotics ◽  
Pcr Identification ◽  
Minimal Concentration ◽  
Carbapenem Antibiotic

ABSTRACT In vitro activity of tebipenem, a new oral carbapenem antibiotic, against clinical Haemophilus influenzae isolates was compared with those of 8 reference agents. Isolates were classified into 6 resistance classes after PCR identification of β-lactamase genes and ftsI gene mutations. For all isolates, the minimal concentration at which 90% of isolates were inhibited was lower for tebipenem than for the reference oral antibiotics, except for cefditoren. Tebipenem also showed excellent bactericidal activity against β-lactamase-nonproducing, ampicillin-resistant isolates.

In vitro activity of cefpirome compared with other third generation cephalosporins against nosocomial isolates in Argentina

Infection ◽  
1990 ◽  
Vol 18 (3) ◽  
pp. 193-195
Author(s):  
J. M. Casellas ◽  
Mirta Goldberg ◽  
Nora Orellana ◽  
Maria Isabel Morosini ◽  
Maria Cristina Negri ◽  
...  
Keyword(s):  
Vitro Activity ◽  
Third Generation ◽  
In Vitro Activity ◽  
Third Generation Cephalosporins
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