Coronary stent fracture and restenosis in the drug-eluting stent era: Do we have clues of management?

2007 ◽  
Vol 120 (3) ◽  
pp. 417-419 ◽  
Author(s):  
Eung Ju Kim ◽  
Seung-Woon Rha ◽  
Sunil P. Wani ◽  
Soon Yong Suh ◽  
Cheol Ung Choi ◽  
...  
2017 ◽  
Vol 58 (6) ◽  
pp. 861-867 ◽  
Author(s):  
Yasuhiro Uchida ◽  
Satoshi Ichimiya ◽  
Hideki Ishii ◽  
Hideo Oishi ◽  
Toshijiro Aoki ◽  
...  

2015 ◽  
Vol 28 (4) ◽  
pp. 365-373 ◽  
Author(s):  
Satoru Mitomo ◽  
Toru Naganuma ◽  
Kensuke Takagi ◽  
Charis Costopoulos ◽  
Shotaro Nakamura ◽  
...  

2016 ◽  
Vol 17 (6) ◽  
pp. 404-411 ◽  
Author(s):  
Alfazir Omar ◽  
Lakshmana K. Pendyala ◽  
John A. Ormiston ◽  
Ron Waksman

2018 ◽  
Vol 11 (3) ◽  
pp. 316-318
Author(s):  
Nilesh Pareek ◽  
Athanasios Kosovitsas ◽  
Michael Rubens ◽  
Ranil de Silva

2019 ◽  
Vol 34 (10) ◽  
pp. 1589-1594
Author(s):  
Yasunari Sakamoto ◽  
Masahiro Yamawaki ◽  
Motoharu Araki ◽  
Norihiro Kobayashi ◽  
Shinsuke Mori ◽  
...  

2009 ◽  
Vol 10 (3) ◽  
pp. 166-171 ◽  
Author(s):  
Adnan K. Chhatriwalla ◽  
Akin Cam ◽  
Samuel Unzek ◽  
Deepak L. Bhatt ◽  
Russell E. Raymond ◽  
...  

2009 ◽  
Vol 53 (3) ◽  
pp. 422-428 ◽  
Author(s):  
Shin Eun Lee ◽  
Myung Ho Jeong ◽  
In Soo Kim ◽  
Jum Suk Ko ◽  
Min Goo Lee ◽  
...  

Thrombosis ◽  
2012 ◽  
Vol 2012 ◽  
pp. 1-16 ◽  
Author(s):  
Fumiyuki Otsuka ◽  
Masataka Nakano ◽  
Elena Ladich ◽  
Frank D. Kolodgie ◽  
Renu Virmani

Several randomized and observational studies have reported steady increase in cumulative incidence of late and very late ST (LST/VLST) following first-generation drug-eluting stents (DES: sirolimus-(SES) and paclitaxel-(PES)) up to 5 years. Pathologic studies have identified uncovered struts as the primary substrate responsible for LST/VLST following DES, where delayed arterial healing is associated with stent struts penetrating into the necrotic core, long/overlapping stents, and bifurcation stenting especially in flow divider region. Grade V stent fracture also induces LST/VLST and restenosis. Hypersensitivity reaction is exclusive to SES as an etiology of LST/VLST, whereas malapposition secondary to excessive fibrin deposition is associated with PES. Uncovered struts can be identified in SES and PES with duration of implant beyond 12 months, particularly in stents placed for “off-label” indications. Neoatherosclerosis is another important contributing factor for VLST in DES and bare metal stents (BMS); however, DES shows rapid and more frequent development of neoatherosclerosis than BMS. Future pathologic studies should address the long-term safety of newer generation DES including zotarolimus- and everolimus-eluting stents in terms of the improvement in reendothelialization, decreased inflammation and fibrin deposition as well as a lower incidence of stent fracture-related adverse events, and reduced neoatherosclerosis, which likely contribute to the decreased risk of LST/VLST and better patient outcomes.


Sign in / Sign up

Export Citation Format

Share Document