Cervical cancer screening programs and guidelines in low- and middle-income countries

2016 ◽  
Vol 134 (3) ◽  
pp. 239-246 ◽  
Author(s):  
Brody Olson ◽  
Beth Gribble ◽  
Jasmyni Dias ◽  
Cassie Curryer ◽  
Kha Vo ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Middle Income ◽  
Screening Programs ◽  
Middle Income Countries ◽  
Low And Middle Income

Clinical trial to implementation: Cost and effectiveness considerations for scaling up cervical cancer screening in low- and middle-income countries

2016 ◽  
Vol 7 ◽  
pp. 4-11 ◽  
Author(s):  
Sujha Subramanian ◽  
Rengaswamy Sankaranarayanan ◽  
Pulikkottil Okkuru Esmy ◽  
Jissa Vinoda Thulaseedharan ◽  
Rajaraman Swaminathan ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Cervical Cancer ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Scaling Up ◽  
Implementation Cost ◽  
Middle Income ◽  
Middle Income Countries ◽  
Low And Middle Income

scholarly journals Cost-effectiveness of cervical cancer screening methods in low- and middle-income countries: A systematic review

2017 ◽  
Vol 141 (3) ◽  
pp. 437-446 ◽  
Author(s):  
Alex K. Mezei ◽  
Heather L. Armstrong ◽  
Heather N. Pedersen ◽  
Nicole G. Campos ◽  
Sheona M. Mitchell ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cervical Cancer ◽  
Cost Effectiveness ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Screening Methods ◽  
Middle Income ◽  
Middle Income Countries ◽  
Low And Middle Income

Barriers affecting uptake of cervical cancer screening in low and middle income countries: A systematic review

2018 ◽  
Vol 55 (4) ◽  
pp. 318 ◽  
Author(s):  
Smita Asthana ◽  
Pradeep Devarapalli ◽  
Satyanarayana Labani ◽  
Narayanasetti Nagarjuna ◽  
Poonam Panchal
Keyword(s):  
Systematic Review ◽  
Cervical Cancer ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Middle Income ◽  
Middle Income Countries ◽  
Low And Middle Income

scholarly journals Lifetime Prevalence of Cervical Cancer Screening in 55 Low- and Middle-Income Countries

JAMA ◽  
2020 ◽  
Vol 324 (15) ◽  
pp. 1532
Author(s):  
Julia M. Lemp ◽  
Jan-Walter De Neve ◽  
Hermann Bussmann ◽  
Simiao Chen ◽  
Jennifer Manne-Goehler ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Lifetime Prevalence ◽  
Middle Income ◽  
Middle Income Countries ◽  
Low And Middle Income

scholarly journals The Vaginal Microbiome and Cervical Cancer Screening in Low- and Middle-Income Countries

2019 ◽  
Vol 5 (Supplement_1) ◽  
pp. 6-6
Author(s):  
Supriya D. Mehta
Keyword(s):  
Cervical Cancer ◽  
Cancer Screening ◽  
Cervical Intraepithelial Neoplasia ◽  
Cervical Cancer Screening ◽  
Intraepithelial Neoplasia ◽  
Vaginal Microbiome ◽  
Middle Income ◽  
Middle Income Countries ◽  
Cancer Pathogenesis ◽  
Low And Middle Income

PURPOSE Globally, cervical cancer affects more than a half-million women each year, with disproportionate incidence and mortality for women in low- and middle-income countries. Early detection through cervical cancer screening saves lives but is hampered by poor coverage, suboptimal detection accuracy, and lack of access to and delays in effective treatment. METHODS Emerging evidence that indicates how the vaginal microbiome can modify progression of human papillomavirus (HPV) infection and cervical cancer pathogenesis is surveyed. This presentation features a discussion of how the vaginal microbiome may affect cervical cancer screening and how cervical cancer screening may incorporate vaginal microbiome health in low- and middle-income countries. RESULTS Vaginal dysbiosis as a clinical syndrome may be called bacterial vaginosis (BV), a condition that represents a shift from a Lactobacillus-dominant vaginal microbiome to one that is polymicrobial and often associated with increased mucosal inflammation. Meta-analyses and prospective studies demonstrate an association between vaginal dysbiosis and increased risk of HPV incidence and persistence and high-grade lesions and cancer. Increasing vaginal microbiome diversity is associated with progression of cervical intraepithelial neoplasia. Vaginal microbiota that are associated with greater likelihood of HPV detection in molecular studies are also commonly associated with BV. There are numerous challenges to incorporating microbiome measurement in population-level cervical cancer screening and unanswered research questions on its immediate utility. BV may serve as a measure of vaginal microbiome health, although there are no guidelines or recommendations for regular BV screening and treatment. CONCLUSION Ongoing and planned longitudinal studies should evaluate BV screening in association with high-risk HPV, results of cervical cancer screening, and progression of cervical intraepithelial neoplasia to assess the utility of BV screening and treatment as an adjunct to cervical cancer screening and potential intervention.

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