Staphylococcus aureus in the airways of cystic fibrosis patients - A retrospective long-term study

2018 ◽  
Vol 308 (6) ◽  
pp. 631-639 ◽  
Author(s):  
Mathias Schwerdt ◽  
Claudia Neumann ◽  
Bianca Schwartbeck ◽  
Stefanie Kampmeier ◽  
Susann Herzog ◽  
...  
1979 ◽  
Vol 82 (3) ◽  
pp. 369-384 ◽  
Author(s):  
Ulrika Ransjö

SUMMARYPrevious investigations have shown that cross-contamination in a burn unit is mainly clothes-borne. New barrier garments have been designed and tried experimentally. The aim of the present study was to investigate the effects of different clothing routines on cross-contamination. In a long-term study, the rates and routes of colonizations withStaphylococcus aureus, Streptococcusgroups A, B, C, F, and G andPseudomonas aeruginosawere examined. The exogenous colonization rates were, withS. aureus77%, withStreptococcusspecies 52% and withPs. aeruginosa32%. The colonization rate withPs. aeruginosawas higher in patients with larger burns. Patients dispersedStreptococcusandPs. aeruginosaas well asS. aureusinto the air of their rooms in considerable amounts, but dispersers were not more important as sources of cross-colonization than non-dispersers. In comparison of clothing routines, there was no difference in overall colonization rates. The newly designed barrier garment that was made from apparently particle-tight material did not reduce the transfer of bacteria from patient to patient. A less rigid routine than that previously used did not increase the risk of cross-contamination. A thorough change of barrier dress after close contact nursing delayed the first exogenousS. aureuscolonization from day 6 to day 14 after admission. This routine might be recommended for clinical use. Otherwise, methods must be developed for adequate selection of materials intended for barrier garments.


PEDIATRICS ◽  
1966 ◽  
Vol 38 (4) ◽  
pp. 657-659
Author(s):  
MARGARET MULLINGER ◽  
MILAGROS PALASI

Pancreatic exocrine functional capacity may be measured directly by collection and evaluation of duodenal aspirate. Pancreatic drainage is time consuming, uncomfortable for the patient, and presents difficulties in obtaining all of the duodenal secretion separated from gastric juice over specified time periods. It is particularly difficult in neonates because of their size. The development of specific substrates for trypsin and chymotrypsin has made possible the accurate measurement of these enzymes in the stools. [SEE TABLE I IN SOURCE PDF]. As part of a long term study of pancreatic activity in children with cystic fibrosis, a study of fresh spot stool specimens obtained from healthy newborn infants was undertaken, with a view to establishing normal values as a tool in the early diagnosis of cystic fibrosis.


1999 ◽  
Vol 135 (5) ◽  
pp. 601-610 ◽  
Author(s):  
Andrew P. Feranchak ◽  
Marci K. Sontag ◽  
Jeffrey S. Wagener ◽  
Keith B. Hammond ◽  
Frank J. Accurso ◽  
...  

PEDIATRICS ◽  
1958 ◽  
Vol 22 (5) ◽  
pp. 990-990

The extent to which the clinical recognition of the condition termed cystic fibrosis of the pancreas has progressed, as well as the limitations of this term, are revealed in a study of 105 patients from a single clinic, followed from 5 to 14 years. The authors have devised a somewhat complicated scheme for evaluation of the clinical condition of patients with this disease and the effects of therapy. When a truly satisfactory treatment is available we shall probably not need a complicated scheme to appraise the results. Here once again it may be seen that some patients with this disease may survive for long periods without the benefit of medical care or regardless of the therapy they may have received. Ten patients in the series had reached the age of 15 years or over at the time of the report; in 7 of these the diagnosis was not established until the age of 8 years or over. However, the authors point out that the duration of life prior to diagnosis may not be a measure of the severity of the disease. That the prognosis has improved is indicated by the finding that prior to 1948 the average age at death was 12 months, and during the period from 1951 through 1956 the average age at death was 59 months. The authors realize that the prognosis is largely dependent upon the course and severity of the pulmonary involvement. One of the principle mysteries in this disease is the variability in the effect of the fundamental process on the various susceptible organs.


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