Binder-free twin-screw melt granulation: an effective approach to manufacture high-dose API formulations

2021 ◽  
pp. 120886
Author(s):  
Ivana Cotabarren ◽  
Thamer Omar ◽  
Fernando J. Muzzio
Keyword(s):  
High Dose ◽  
Twin Screw ◽  
Binder Free ◽  
Melt Granulation

Application of Melt Granulation Technology Using Twin-screw Extruder in Development of High-dose Modified-Release Tablet Formulation

2011 ◽  
Vol 100 (5) ◽  
pp. 1923-1934 ◽  
Author(s):  
Madhav Vasanthavada ◽  
Yanfeng Wang ◽  
Thomas Haefele ◽  
Jay P. Lakshman ◽  
Manisha Mone ◽  
...  
Keyword(s):  
Tablet Formulation ◽  
High Dose ◽  
Twin Screw Extruder ◽  
Modified Release ◽  
Screw Extruder ◽  
Twin Screw ◽  
Granulation Technology ◽  
Melt Granulation ◽  
Release Tablet

Melt granulation: A comparison of granules produced via high-shear mixing and twin-screw granulation

2020 ◽  
Vol 591 ◽  
pp. 119941
Author(s):  
Kristina E. Steffens ◽  
Marvin B. Brenner ◽  
Michael U. Hartig ◽  
Marius Monschke ◽  
Karl G. Wagner
Keyword(s):  
High Shear ◽  
Twin Screw ◽  
Shear Mixing ◽  
Twin Screw Granulation ◽  
Melt Granulation

Hot-Melt Granulation in a Twin Screw Extruder: Effects of Processing on Formulations with Caffeine and Ibuprofen

2013 ◽  
Vol 102 (12) ◽  
pp. 4330-4336 ◽  
Author(s):  
Sharleen Weatherley ◽  
B.O. MU ◽  
Michael R. Thompson ◽  
Paul J. Sheskey ◽  
Kevin P. O'Donnell
Keyword(s):  
Twin Screw Extruder ◽  
Screw Extruder ◽  
Twin Screw ◽  
Hot Melt Granulation ◽  
Hot Melt ◽  
Melt Granulation

Vibrational spectroscopy to support the link between rheology and continuous twin-screw melt granulation on molecular level: A case study

2016 ◽  
Vol 103 ◽  
pp. 127-135 ◽  
Author(s):  
Tinne Monteyne ◽  
Liza Heeze ◽  
Klaus Oldörp ◽  
Chris Vervaet ◽  
Jean-Paul Remon ◽  
...  
Keyword(s):  
Vibrational Spectroscopy ◽  
Molecular Level ◽  
Twin Screw ◽  
Melt Granulation

Effect of Hydroxypropyl Cellulose Level on Twin-Screw Melt Granulation of Acetaminophen

2020 ◽  
Vol 21 (7) ◽  
Author(s):  
Tongzhou Liu ◽  
Shubhajit Paul ◽  
Brian T Beeson ◽  
Johnny Alexander ◽  
Fengyuan Yang ◽  
...  
Keyword(s):  
Hydroxypropyl Cellulose ◽  
Twin Screw ◽  
Melt Granulation

Twin-screw melt granulation: Current progress and challenges

2020 ◽  
Vol 588 ◽  
pp. 119670 ◽  
Author(s):  
Nada Kittikunakorn ◽  
Tongzhou Liu ◽  
Feng Zhang
Keyword(s):  
Twin Screw ◽  
Melt Granulation
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