Quality of Life in Patients Treated with Gamma Knife Stereotactic Radiosurgery for Acoustic Neuroma

2009 ◽  
Vol 75 (3) ◽  
pp. S518
Author(s):  
D. Bojrab ◽  
E. Martinez Perez ◽  
I. Grills ◽  
Y. Hahn ◽  
T. Pfannenstiel ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Stereotactic Radiosurgery ◽  
Gamma Knife ◽  
Acoustic Neuroma ◽  
Gamma Knife Stereotactic Radiosurgery

Malignant Transformation of Acoustic Neuroma 10 Years after Gamma-Knife Stereotactic Radiosurgery

Skull Base ◽  
2009 ◽  
Vol 19 (01) ◽  
Author(s):  
Andreas Demetriades ◽  
Nicholas Saunders ◽  
Peter Rose ◽  
Cyril Fisher ◽  
Robert Tranter ◽  
...  
Keyword(s):  
Stereotactic Radiosurgery ◽  
Malignant Transformation ◽  
Gamma Knife ◽  
Acoustic Neuroma ◽  
Gamma Knife Stereotactic Radiosurgery

Cognitive and psychosocial outcomes following stereotactic radiosurgery for acoustic neuroma

2021 ◽  
pp. 1-9
Author(s):  
Naomi Brownlee ◽  
Colin Wilson ◽  
David B. Curran ◽  
Gavin Wright ◽  
Tom Flannery ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Psychological Distress ◽  
Stereotactic Radiosurgery ◽  
Acoustic Neuroma ◽  
Visual Memory ◽  
Radiation Treatment ◽  
Psychosocial Outcomes ◽  
Subjective Cognitive Decline ◽  
Eighth Cranial Nerve

BACKGROUND: Acoustic Neuroma (AN) is a benign tumour of the eighth cranial nerve. Stereotactic Radiosurgery (SRS) is a common treatment approach. Studies have explored the primary effects of SRS and documented equivalent efficacy for tumour control compared to neurosurgery. OBJECTIVE: Examine the longer term cognitive and psychosocial outcomes of SRS in non-Neurofibromatosis Type II patients utilising both objective and subjective cognitive outcomes associated with quality of life and health related distress. METHODS: Nineteen individuals treated via SRS were assessed using a battery of standardised psychometric tests as well as measures of quality of life and psychological distress. RESULTS: Participants had largely preserved cognitive function except for processing speed, aspects of attention and visual memory relative to age norms. Self-reported quality of life was better than in other AN population studies. Level of psychological distress was equivalent to general population norms. More than half of participants reported subjective cognitive decline though this was not fully supported by objective testing. Subjective cognitive complaints may be associated with lower reported quality of life. CONCLUSIONS: Results are largely consistent with previous findings on the effects of SRS in other clinical groups, which supports SRS as a targeted radiation treatment for AN.

Safety and Efficacy of Tiered Limited-Dose Gamma Knife Stereotactic Radiosurgery for Unilateral Acoustic Neuroma

2004 ◽  
Vol 82 (4) ◽  
pp. 147-152 ◽  
Author(s):  
Howard J. Landy ◽  
Arnold M. Markoe ◽  
Xiaodong Wu ◽  
Sherri J. Patchen ◽  
Isildinha M. Reis ◽  
...  
Keyword(s):  
Stereotactic Radiosurgery ◽  
Gamma Knife ◽  
Acoustic Neuroma ◽  
Safety And Efficacy ◽  
Gamma Knife Stereotactic Radiosurgery

scholarly journals Radiomic assessment of the progression of acoustic neuroma after gamma knife stereotactic radiosurgery

2019 ◽  
Vol 9 (2) ◽  
pp. 1
Author(s):  
Ganesh Narayanasamy ◽  
Geoffrey Zhang ◽  
Eric Siegel ◽  
Graham Campbell ◽  
Eduardo G. Moros ◽  
...  
Keyword(s):  
Stereotactic Radiosurgery ◽  
Gamma Knife ◽  
Acoustic Neuroma ◽  
Roc Analysis ◽  
Operating Characteristic ◽  
Hearing Preservation ◽  
Magnetic Resonance Images ◽  
Acoustic Neuromas ◽  
Gray Tone ◽  
Gamma Knife Stereotactic Radiosurgery

Introduction: The aim of this study was to determine whether radiomic features measured at baseline in Magnetic Resonance images (MRI) of acoustic neuromas (AN) can predict Gamma Knife (GK) treatment outcome.Methods: The study was conducted on pre- and post-GK MRI-T2 scans of 32 patients with AN who underwent stereotactic radiosurgery (SRS) for 12 Gy dose. Radiomic features extracted include Intensity, Fractals, Laplacian of Gaussian and textural Co-Occurrence, Run-length (RL), Size Zone, and Neighborhood Gray-Tone Difference matrices (NGTDM) features. Subjects were classified as treatment failures (TF) if tumor volume increased > 10%. Pre- and post-SRS audiology reports were utilized in hearing evaluation.Results: Fifteen subjects (47%) qualified as TFs. In univariate receiver operating characteristic (ROC) analysis, two radiomicfeatures, complexity in NGTDM and run percentage in RL, displayed areas under curves of > 0.65.Conclusion: This initial radiomic study establishes features that illustrates the prognostic ability of the SRS treatment in acousticneuroma. Hearing preservation was achieved in a majority of acoustic neuroma patients treated in Gamma Knife.

Sign in / Sign up

Export Citation Format

Share Document