Quality of Life of Acoustic Neuroma Patients Treated with Gamma Knife Radiosurgery

2009 ◽  
Vol 75 (3) ◽  
pp. S517
Author(s):  
I.U. Ahmad ◽  
M. Vlachaki
Keyword(s):  
Quality Of Life ◽  
Gamma Knife ◽  
Acoustic Neuroma ◽  
Gamma Knife Radiosurgery

Impact on the quality of life of patients with arteriovenous malformations during the latent interval between gamma knife radiosurgery and lesion obliteration

2002 ◽  
Vol 97 ◽  
pp. 471-473 ◽  
Author(s):  
Erica Ho Pik Lai ◽  
Samuel Leung Cheong Lun
Keyword(s):  
Quality Of Life ◽  
Gamma Knife ◽  
Arteriovenous Malformations ◽  
Gamma Knife Radiosurgery ◽  
Medical Problems ◽  
Waiting Period ◽  
Content Type ◽  
Latent Interval ◽  
Fine Print

Object. The aim of this study was to measure the quality of life (QOL) in patients with cerebral arteriovenous malformations (AVMs) receiving gamma knife treatment before total AVM obliteration. Quality of life was assessed as it related to the knowledge of rebleeding risk during the waiting period, AVM symptoms, and previous bleeding. Methods. Thirty-nine patients age 18 years or older without other medical problems were asked to complete a questionnaire that included demographic variables, immediate effect of gamma knife radiosurgery, symptoms of AVM, previous hemorrhage, and the Duke—University of North Carolina Health Profile (63 items). Conclusions. The QOL of patients with cerebral AVM during the waiting period after undergoing gamma knife treatment was affected by irreversible physical disabilities rather than the knowledge of hemorrhage risk and bleeding experience.

scholarly journals Gamma Knife Radiosurgery for Vestibular Schwannomas and Quality of Life Evaluation

2017 ◽  
Vol 95 (3) ◽  
pp. 166-173 ◽  
Author(s):  
Oren Berkowitz ◽  
Yueh-Ying Han ◽  
Evelyn O. Talbott ◽  
Aditya K. Iyer ◽  
Hideyuki Kano ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Gamma Knife ◽  
Gamma Knife Radiosurgery ◽  
Vestibular Schwannomas ◽  
Life Evaluation

Long-Term Follow-Up of Quality of Life after Gamma Knife Radiosurgery Treatment for Arteriovenous Malformations

Radiosurgery ◽  
2006 ◽  
pp. 211-220
Author(s):  
Michael J. Jr. Musacchio ◽  
Brian Kuchay ◽  
Nimesh H. Patel ◽  
Sepehr B. Sani ◽  
Demetrius K. Lopes
Keyword(s):  
Quality Of Life ◽  
Gamma Knife ◽  
Arteriovenous Malformations ◽  
Gamma Knife Radiosurgery ◽  
Long Term Follow Up

Gamma Knife Radiosurgery for Low-Grade Gliomas: Clinical Results at Long-Term Follow-Up of Tumor Control and Patients' Quality of Life

2017 ◽  
Vol 101 ◽  
pp. 540-553 ◽  
Author(s):  
Filippo Gagliardi ◽  
Michele Bailo ◽  
Alfio Spina ◽  
Carmine A. Donofrio ◽  
Nicola Boari ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Gamma Knife ◽  
Gamma Knife Radiosurgery ◽  
Clinical Results ◽  
Tumor Control ◽  
Low Grade ◽  
Long Term Follow Up

scholarly journals Quality of life after gamma knife radiosurgery treatment in patients with a vestibular schwannoma: the patient’s perspective

2009 ◽  
Vol 267 (6) ◽  
pp. 867-873 ◽  
Author(s):  
Ferdinand C. A. Timmer ◽  
Anniek E. P. van Haren ◽  
Jef J. S. Mulder ◽  
Patrick E. J. Hanssens ◽  
Jacobus J. van Overbeeke ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Gamma Knife ◽  
Vestibular Schwannoma ◽  
Gamma Knife Radiosurgery ◽  
Patient’S Perspective

scholarly journals Trigeminal Neuralgia: Outcomes after Gamma Knife Radiosurgery

2009 ◽  
Vol 36 (1) ◽  
pp. 78-82 ◽  
Author(s):  
Henri Knafo ◽  
Brendan Kenny ◽  
David Mathieu
Keyword(s):  
Quality Of Life ◽  
Side Effects ◽  
Pain Relief ◽  
Trigeminal Neuralgia ◽  
Gamma Knife ◽  
Cox Regression ◽  
Statistical Significance ◽  
Gamma Knife Radiosurgery ◽  
Cox Regression Analysis

Background:Trigeminal neuralgia (TN) often remains difficult to treat despite multiple available medications, and can severely impact on the quality of life of affected patients. Gamma knife radiosurgery has recently emerged as a minimally-invasive alternative to surgery for patients suffering from drug-resistant TN. The goal of this study was to report the short-term efficacy of gamma knife radiosurgery for TN and assess its impact on the quality of life of patients treated in the first 18 months of our experience.Methods:Patients with medically-refractory TN or with unacceptable drug side effects were considered for radiosurgery. A maximum dose of 80 Gy was administered to the affected nerve using a single 4-mm isocenter. Follow-up assessments were made at 2, 4 and 6 months, with evaluation of pain relief, drug reduction and quality of life. Factors impacting treatment response were assessed using Cox regression analysis.Results:A total of 67 patients were treated. Significant pain relief was seen in 77.6% of patients, including 32.6% who became pain-free. Patients were able to discontinue all medications in 34.3% or reduce drug intake by more than 50% in an additional 28.4% of cases. No variable was found to predict pain relief although older age (>66 years) approached statistical significance. Sensory side effects were seen in 14.9% of patients. Quality of life improved in the majority of patients after radiosurgery.Conclusions:Gamma knife radiosurgery is a safe and effective management alternative for trigeminal neuralgia, providing good or excellent pain relief and improvement in quality of life in the majority of patients with few side effects.

scholarly journals Outcome of Intracerebral Cavernoma Treated by Gamma Knife Radiosurgery Based on a Double-blind Assessment of Treatment Indication

2021 ◽  
Author(s):  
Chiung-Chyi Shen ◽  
Ming-Hsi Sun ◽  
Men-Yin Yang ◽  
Weir Chiang You ◽  
Meei-Ling Sheu ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Gamma Knife ◽  
Seizure Control ◽  
Gamma Knife Radiosurgery ◽  
Neurological Deficits ◽  
Seizure Freedom ◽  
Double Blind ◽  
Highly Correlated

Abstract Background: The benefit and the risk profile of Gamma Knife radiosurgery for intracerebral cavernoma remains incompletely defined in part due to the natural history of low incidence of bleeding and spontaneous regression of this vascular malformation. In this study, we retrieved cases from a prospectively collected database to assess the outcome of intracerebral cavernoma treated with Gamma Knife using a double blinded review process for treatment.Methods: From 2003 to 2018, there were 94 cases of cavernoma treated by Gamma Knife radiosurgery doubly blinded assessed by two experienced neurological and approved for Gamma Knife treatment. All the patients received Gamma Knife radiosurgery with margin dose of 11-12 Gy and afterwards were assessed for neurological outcome, radiologic response, and quality of life.Results: The median age of the patients was 48(15-85) years with median follow up of 77(26-180) months post SRS. The mean treated volume was 1.93±3.45cc. In those who has pre-SRS epilepsy, 7 of 16(43.7%) achieved seizure freedom (Engel I/II) and 9 of 16 (56.3%) achieved decreased seizures (Engel III) after SRS. Rebleeding occurred in 2 cases (2.1%) at 13 and 52 months post SRS. The radiologic assessment demonstrated 20 (21.3%) cases of decreased cavernoma volume, 69(73.4%) were stable, and 5 (7.3%) increased size. Eight-seven of 94 (92.5%) cases at the last follow up achieve improvement in their quality of life, but 7 cases (7.4%) showed a deterioration. In statistical analysis, the effective seizure control class (Engel I/II) was highly correlated with patient harboring a single lesion (p<0.05) and deep seated location of the cavernoma (p<0.01). New neurological deficits were highly correlated with decreased mental (p<0.001) and physical (p<0.05) components of quality of life testing, KPS (p<0.001), deep seated location (p<0.01), and increased nidus volume (p<0.05). Quality of life deterioration either in physical component (p<0.01), mental component (p<0.01), and KPS (p<0.05) was highly correlated with increased cavernoma volume.Conclusion: Low margin dose Gamma Knife radiosurgery for intracerebral cavernoma offers reasonable seizure control and improved quality of life while conferring a low risk of treatment complications including adverse radiation effect.

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