Cognitive and psychosocial outcomes following stereotactic radiosurgery for acoustic neuroma

2021 ◽  
pp. 1-9
Author(s):  
Naomi Brownlee ◽  
Colin Wilson ◽  
David B. Curran ◽  
Gavin Wright ◽  
Tom Flannery ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Psychological Distress ◽  
Stereotactic Radiosurgery ◽  
Acoustic Neuroma ◽  
Visual Memory ◽  
Radiation Treatment ◽  
Psychosocial Outcomes ◽  
Subjective Cognitive Decline ◽  
Eighth Cranial Nerve

BACKGROUND: Acoustic Neuroma (AN) is a benign tumour of the eighth cranial nerve. Stereotactic Radiosurgery (SRS) is a common treatment approach. Studies have explored the primary effects of SRS and documented equivalent efficacy for tumour control compared to neurosurgery. OBJECTIVE: Examine the longer term cognitive and psychosocial outcomes of SRS in non-Neurofibromatosis Type II patients utilising both objective and subjective cognitive outcomes associated with quality of life and health related distress. METHODS: Nineteen individuals treated via SRS were assessed using a battery of standardised psychometric tests as well as measures of quality of life and psychological distress. RESULTS: Participants had largely preserved cognitive function except for processing speed, aspects of attention and visual memory relative to age norms. Self-reported quality of life was better than in other AN population studies. Level of psychological distress was equivalent to general population norms. More than half of participants reported subjective cognitive decline though this was not fully supported by objective testing. Subjective cognitive complaints may be associated with lower reported quality of life. CONCLUSIONS: Results are largely consistent with previous findings on the effects of SRS in other clinical groups, which supports SRS as a targeted radiation treatment for AN.

Psychiatric comorbidities and quality of life in breast cancer patients undergoing radiation treatment: Risk and protective factors

2021 ◽  
pp. 009121742198914
Author(s):  
In Hee Shim ◽  
Chul Won Choi ◽  
Dong Sik Bae ◽  
Su Hong Ha ◽  
Kyung A Kwon ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Psychological Distress ◽  
Protective Factors ◽  
Cancer Patients ◽  
Radiation Treatment ◽  
Risk And Protective Factors ◽  
Breast Cancer Patients ◽  
Psychiatric Comorbidities

Objective The primary goal was to evaluate the prevalence of psychiatric comorbidities and changes in psychological distress levels among breast cancer patients receiving radiotherapy (RT). The secondary goal was to determine risk and protective factors for psychiatric comorbidities of these patients. Methods From June 2018 to November 2019, patients were recruited from the hospital, Department of Psychiatry. Patients completed baseline surveys after seeing their radiation oncologist and prior to the first treatment, which was scheduled to take place within 7 days (visit 1, baseline); visit 2 occurred within 7 days after RT completion, and visit 3 occurred at 6 weeks after RT completion. A total of 99 patients participated in the study at visit 1; 56 patients completed the study through visit 3. Results Although changes in psychiatric comorbidities and overall quality of life were observed in patients with breast cancer prior to, during, and after RT, the differences were not significant among visits. Patients diagnosed with psychiatric comorbidities after RT had exhibited risk factors at previous visits, including preexisting psychiatric comorbidities, functional deterioration, and more severe symptoms related to breast cancer. Based on the results, the psychological characteristics of optimism and resilience can be considered as protective factors for psychiatric comorbidities. Conclusions The results suggest that early detection and follow-up of psychological distress and poor quality of life at the onset of RT are of paramount importance, and that psychosocial interventions to enhance protective factors (optimism and resilience) may be helpful.

The “Promoting Resilience in Stress Management” (PRISM) intervention for adolescents and young adults: A pilot randomized controlled trial.

2017 ◽  
Vol 35 (31_suppl) ◽  
pp. 176-176 ◽  
Author(s):  
Abby R. Rosenberg ◽  
Miranda Bradford ◽  
Victoria Klein ◽  
Nicole Etsekson ◽  
Claire M Wharton ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Young Adults ◽  
Psychological Distress ◽  
Usual Care ◽  
Stress Management ◽  
Meaning Making ◽  
Psychosocial Outcomes ◽  
Adolescents And Young Adults ◽  
Patient Reported

176 Background: Adolescents and Young Adults (AYAs) with cancer are at risk for poor psychosocial outcomes, perhaps because they have yet to learn the skills needed to navigate the burdens of illness. We aimed to determine if a novel, brief, age-appropriate, skills-based intervention would improve psychosocial outcomes. Methods: “Promoting Resilience in Stress Management” (PRISM) is a manualized, brief intervention targeting stress management, goal-setting, cognitive reframing, and meaning-making. It consists of 4, 30-60 minute, in-person, 1:1 sessions plus a facilitated family-meeting. English-speaking AYAs (ages 12-25 years) with new or newly recurrent cancer were randomized to receive either PRISM or non-directive usual psychosocial care. Participants completed patient-reported outcome (PRO) surveys at the time of enrollment and 6 months later. We used mixed effects regression modeling to estimate associations between PRISM and the primary outcome (patient-reported resilience, measured by the Connor-Davidson Resilience Scale [CDRISC-10]) and secondary outcomes (health-related quality of life [PedsQL 4.0 Quality of Life Inventory], hope [Snyder Hope Scale], and psychological distress [Kessler-6 Psychological Distress Scale]) at 6 months. Results: N = 100 AYAs enrolled (78% of approached, n = 50 PRISM, n = 50 usual care) and 92 completed baseline responses (48 PRISM and 44 usual care). Of those who completed baseline, 73% were aged 13-17 years and 27% aged 18-25 years, and 43% were female. Attrition was similar in each arm and primarily due to medical complication and/or death; n = 36 (72%) PRISM and n = 38 (76%) usual care participants completed 6-month PROs. After adjusting for baseline scores, PRISM was associated with improvements in all instruments: Resilience (+2.3, 95% CI 0.7,4.0), quality of life (+6.3 (95% CI -0.8, 13.5), hope (+2.8, 95% CI 0.5, 5.1), and distress (-1.6, 95% CI -3.3, 0.0). Conclusions: A targeted intervention targeting skills for AYAs with cancer was effective in improving patient-centered outcomes. Clinical trial information: NCT02340884.

Long-Term Quality of Life Following Stereotactic Radiosurgery for Vestibular Schwannoma

2012 ◽  
Vol 73 (S 02) ◽  
Author(s):  
J. Thom ◽  
M. Carlson ◽  
J. Jacob ◽  
C. Driscoll ◽  
B. Neff ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Stereotactic Radiosurgery ◽  
Vestibular Schwannoma
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