Head-and-Neck Cancers as Second Primary Following an Index Head-and-Neck Cancer: Population-Based Outcomes Over a 25-Year Period

2013 ◽  
Vol 87 (2) ◽  
pp. S481-S482
Author(s):  
M.S. Tiwana ◽  
J. Wu ◽  
J. Hay ◽  
F. Wong ◽  
W. Cheung ◽  
...  
Author(s):  
Sowjanya Gandla ◽  
Vishal Rao

<p class="abstract"><strong>Background:</strong> The patients with the head and neck cancer are strongly at risk of developing a second primary tumor which can be related to share etiological factors such as tobacco, alcohol and smoking. The aim of the study is to evaluate the percentage of synchronous second primaries and distant metastasis that are identified on PET CT imaging in head and neck cancer patients at initial presentation.</p><p class="abstract"><strong>Methods:</strong> This study is a retrospective observational study. A total of 503 patients with histological confirmation of head and neck cancer and who had undergone 18F FDG PET CT imaging from 2007 to 2013 were included in the study. The PET CT scan images of all 503 patients were reviewed. The patients with PET CT scan images indicating the presence of abnormal metabolic uptake suggestive of additional primary malignant lesion or distant metastasis were identified.  </p><p class="abstract"><strong>Results:</strong> Out of the total 503 patients with histological confirmation of head and neck cancer, 34 patients were excluded due to non-availability of complete details, among the 469 patients of head and neck cancer, 7 patients (1.49%) were diagnosed with synchronous primary tumors and 33 patients (7.03%) were diagnosed with distant metastasis in PET CT imaging at the time of initial presentation.</p><p class="abstract"><strong>Conclusions:</strong> PET CT imaging is a useful tool to detect distant metastasis and second primary synchronous tumors in advanced head and neck cancers. The incidence of distant metastasis is a much more valid indication for the PET CT imaging in advanced head and neck cancers.</p>


Cancer ◽  
2015 ◽  
Vol 121 (9) ◽  
pp. 1436-1445 ◽  
Author(s):  
Amit K. Chowdhry ◽  
Colin McHugh ◽  
Chunkit Fung ◽  
Sughosh Dhakal ◽  
Louis S. Constine ◽  
...  

Head & Neck ◽  
2018 ◽  
Vol 41 (4) ◽  
pp. 1122-1130 ◽  
Author(s):  
Oisín Bugter ◽  
Steffi E. M. van de Ven ◽  
Jose A. Hardillo ◽  
Marco J. Bruno ◽  
Arjun D. Koch ◽  
...  

2016 ◽  
Vol 96 (4) ◽  
pp. 808-819 ◽  
Author(s):  
Mark W. McDonald ◽  
Omid Zolali-Meybodi ◽  
Stephen J. Lehnert ◽  
Neil C. Estabrook ◽  
Yuan Liu ◽  
...  

Oral Oncology ◽  
2010 ◽  
Vol 46 (4) ◽  
pp. 249-254 ◽  
Author(s):  
Min-Chi Chen ◽  
Wei-Chao Huang ◽  
Chunghuang Hubert Chan ◽  
Ping-Tsung Chen ◽  
Kuan-Der Lee

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yannan Wang ◽  
Mengxue Wang ◽  
Yan Tang ◽  
Bincan Sun ◽  
Kai Wang ◽  
...  

Abstract Background Head and neck cancers are aggressive cancers, most clinical studies focused on the prognosis of patients with head and neck cancer. However, perioperative mortality was rarely mentioned. Methods A retrospective analysis was performed using all head and neck cancer patients admitting in the Department of Oral and Maxillofacial Surgery of the Second Xiangya Hospital, Central South University from January 2010 to December 2019. The analysis of overall survival and progression-free survival were performed using the Kaplan–Meier method, and cross tabulation with chi-squared testing was applied to analyze the difference in parameters between groups. Results From January 2010 to December 2019, a total of 6576 patients with head and neck cancers were admitted to our department and 7 died in the hospital, all of whom were middle-aged and elderly patients including 6 males and 1 female. The perioperative mortality rate (POMR) was about 1‰. The causes of death included acute heart failure, rupture of large blood vessels in the neck, hypoxic ischemic encephalopathy due to asphyxia, respiratory failure and cardiopulmonary arrest. Conclusion Preoperative radiotherapy, previous chemotherapy, hypertension, diabetes, advanced clinical stage and postoperative infection are risk factors for perioperative mortality of head and neck cancer.


Sign in / Sign up

Export Citation Format

Share Document