The diagnostic accuracy of dermoscopy for basal cell carcinoma: A systematic review and meta-analysis

2019 ◽  
Vol 80 (5) ◽  
pp. 1380-1388 ◽  
Author(s):  
Ofer Reiter ◽  
Ilit Mimouni ◽  
Michael Gdalevich ◽  
Ashfaq A. Marghoob ◽  
Assi Levi ◽  
...  
Keyword(s):  
Systematic Review ◽  
Basal Cell Carcinoma ◽  
Diagnostic Accuracy ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Meta Analysis

The effectiveness of photodynamic therapy and cryotherapy on patients with basal cell carcinoma: A systematic review and meta‐analysis

2020 ◽  
Vol 33 (6) ◽  
Author(s):  
George Mpourazanis ◽  
Pantelis Mpourazanis ◽  
Georgios Stogiannidis ◽  
Georgios Ntritsos
Keyword(s):  
Systematic Review ◽  
Photodynamic Therapy ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Meta Analysis

scholarly journals Conventional and combination topical photodynamic therapy for basal cell carcinoma: systematic review and meta-analysis

2018 ◽  
Vol 179 (6) ◽  
pp. 1277-1296 ◽  
Author(s):  
N.J. Collier ◽  
A.K. Haylett ◽  
T.H. Wong ◽  
C.A. Morton ◽  
S.H. Ibbotson ◽  
...  
Keyword(s):  
Systematic Review ◽  
Photodynamic Therapy ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Meta Analysis

scholarly journals A Systematic Review and Meta-Analysis of the Accuracy of in VivoReflectance Confocal Microscopy for the Diagnosis of Primary Basal Cell Carcinoma

2019 ◽  
Vol 8 (9) ◽  
pp. 1462 ◽  
Author(s):  
Lupu ◽  
Popa ◽  
Voiculescu ◽  
Caruntu ◽  
Caruntu
Keyword(s):  
Systematic Review ◽  
Confocal Microscopy ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Sensitivity And Specificity ◽  
Basal Cell ◽  
Meta Analysis ◽  
High Sensitivity ◽  
Diagnostic Odds Ratio ◽  
Likelihood Ratios

Basal cell carcinoma (BCC) is the most common cancer worldwide and its incidence is constantly rising. Early diagnosis and treatment can significantly reduce patient morbidity and healthcare costs. The value of reflectance confocal microscopy (RCM) in non-melanoma skin cancer diagnosis is still under debate. This systematic review and meta-analysis were conducted to assess the diagnostic accuracy of RCM in primary BCC. PubMed, Google Scholar, Scopus, and Web of Science databases were searched up to July 05, 2019, to collect articles concerning primary BCC diagnosis through RCM. The studies’ methodological quality was assessed by the QUADAS-2 tool. The meta-analysis was conducted using Stata 13.0, RevMan 5.0, and MetaDisc 1.4 software. We included 15 studies totaling a number of 4163 lesions. The pooled sensitivity and specificity were 0.92 (95% CI, 0.87–0.95; I2= 85.27%) and 0.93 (95% CI, 0.85–0.97; I2= 94.61%), the pooled positive and negative likelihood ratios were 13.51 (95% CI, 5.8–31.37; I2= 91.01%) and 0.08 (95% CI, 0.05–0.14; I2= 84.83%), and the pooled diagnostic odds ratio was 160.31 (95% CI, 64.73–397.02; I2=71%). Despite the heterogeneity and risk of bias, this study demonstrates that RCM, through its high sensitivity and specificity, may have a significant clinical impact on the diagnosis of primary BCC.

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