scholarly journals Advanced Heart Failure Therapies for Adults With Congenital Heart Disease

2019 ◽  
Vol 74 (18) ◽  
pp. 2295-2312 ◽  
Author(s):  
Michael M. Givertz ◽  
Ersilia M. DeFilippis ◽  
Michael J. Landzberg ◽  
Sean P. Pinney ◽  
Ronald K. Woods ◽  
...  
Keyword(s):  
Heart Failure ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Advanced Heart Failure

scholarly journals Pulsed Levosimendan in advanced heart failure due to congenital heart disease: a case series

2020 ◽  
Vol 4 (3) ◽  
pp. 1-6
Author(s):  
James Cranley ◽  
Antonia Hardiman ◽  
Leisa J Freeman
Keyword(s):  
Heart Failure ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Case Series ◽  
Advanced Heart Failure ◽  
Good Evidence ◽  
Case Summary ◽  
Acute Decompensation

Abstract Background Levosimendan is a non-adrenergic calcium-sensitizing agent with positive inotropic and vasodilatory effects. Its use in acute decompensation of heart failure is established. Good evidence now exists for repetitive infusions of Levosimendan to improve symptoms and reduce hospitalization in advanced heart failure (AdHF) populations. Its use in heart failure resulting from congenital heart disease is not yet commonplace. Case summary We present three cases in which pulsed Levosimendan was used in the management of AdHF secondary to underlying congenital heart disease. There was symptomatic and biomarker evidence of improvement. Discussion Intermittent Levosimendan may represent a valuable therapy to reduce hospitalization and improve quality of life in adults with congenital heart conditions.

scholarly journals Advanced Heart Failure in Adults With Congenital Heart Disease

2020 ◽  
Vol 8 (2) ◽  
pp. 87-99 ◽  
Author(s):  
Jonathan N. Menachem ◽  
Kelly H. Schlendorf ◽  
Jeremy A. Mazurek ◽  
David P. Bichell ◽  
D. Marshall Brinkley ◽  
...  
Keyword(s):  
Heart Failure ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Advanced Heart Failure
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