Significant mortality, morbidity and resource utilization associated with advanced heart failure in congenital heart disease in children and young adults

2019 ◽  
Vol 209 ◽  
pp. 9-19 ◽  
Author(s):  
Danielle S. Burstein ◽  
Pirouz Shamszad ◽  
Dingwei Dai ◽  
Christopher S. Almond ◽  
Jack F. Price ◽  
...  
2006 ◽  
Vol 29 (4) ◽  
pp. 386-392 ◽  
Author(s):  
JORG NOTHROFF ◽  
KAMBIZ NOROZI ◽  
VALENTIN ALPERS ◽  
JAN O. ARNHOLD ◽  
ARMIN WESSEL ◽  
...  

2020 ◽  
Vol 4 (3) ◽  
pp. 1-6
Author(s):  
James Cranley ◽  
Antonia Hardiman ◽  
Leisa J Freeman

Abstract Background Levosimendan is a non-adrenergic calcium-sensitizing agent with positive inotropic and vasodilatory effects. Its use in acute decompensation of heart failure is established. Good evidence now exists for repetitive infusions of Levosimendan to improve symptoms and reduce hospitalization in advanced heart failure (AdHF) populations. Its use in heart failure resulting from congenital heart disease is not yet commonplace. Case summary We present three cases in which pulsed Levosimendan was used in the management of AdHF secondary to underlying congenital heart disease. There was symptomatic and biomarker evidence of improvement. Discussion Intermittent Levosimendan may represent a valuable therapy to reduce hospitalization and improve quality of life in adults with congenital heart conditions.


2021 ◽  
pp. 1-4
Author(s):  
Jose M. Arribas-Leal ◽  
Maria Garcia-Vieites ◽  
Antonio Jimenez-Aceituna ◽  
Sergio Canovas-Lopez ◽  
Francisco Gutierrez ◽  
...  

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