The Anti-Inflammatory Effect of Ciglitazone is Partially Mediated by Glucocorticoid Induced Leucine Zipper in Human Airway Epithelial Cells

2007 ◽  
Vol 119 (1) ◽  
pp. S127
Author(s):  
A.L. Wagelie-Steffen ◽  
J. Eddleston ◽  
J. Herschbach ◽  
B.L. Zuraw
Keyword(s):  
Epithelial Cells ◽  
Leucine Zipper ◽  
Airway Epithelial Cells ◽  
Airway Epithelial ◽  
Human Airway ◽  
Anti Inflammatory ◽  
Inflammatory Effect ◽  
Human Airway Epithelial Cells

Synthesis and anti-inflammatory effect of lipoxins in human airway epithelial cells

2007 ◽  
Vol 61 (5) ◽  
pp. 261-267 ◽  
Author(s):  
Caroline Bonnans ◽  
Delphine Gras ◽  
Claude Chavis ◽  
Brigitte Mainprice ◽  
Isabelle Vachier ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Airway Epithelial Cells ◽  
Airway Epithelial ◽  
Human Airway ◽  
Anti Inflammatory ◽  
Inflammatory Effect ◽  
Human Airway Epithelial Cells

scholarly journals Dexamethasone Inhibits Repair of Human Airway Epithelial Cells Mediated by Glucocorticoid-Induced Leucine Zipper (GILZ)

PLoS ONE ◽  
2013 ◽  
Vol 8 (4) ◽  
pp. e60705 ◽  
Author(s):  
Jingyue Liu ◽  
Mingxiang Zhang ◽  
Chao Niu ◽  
Zhengxiu Luo ◽  
Jihong Dai ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Leucine Zipper ◽  
Airway Epithelial Cells ◽  
Airway Epithelial ◽  
Human Airway ◽  
Human Airway Epithelial Cells

Omeprazole Has Anti-Inflammatory Effects on Type 2 Cytokine-Stimulated Human Airway Epithelial Cells

2015 ◽  
Vol 135 (2) ◽  
pp. AB81 ◽  
Author(s):  
Jin Young Min ◽  
Robert C. Kern ◽  
Christopher J. Ocampo ◽  
Tetsuya Homma ◽  
David B. Conley ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Airway Epithelial Cells ◽  
Airway Epithelial ◽  
Human Airway ◽  
Anti Inflammatory ◽  
Human Airway Epithelial Cells

ICAM-1-independent adhesion of neutrophils to phorbol ester-stimulated human airway epithelial cells

1999 ◽  
Vol 277 (3) ◽  
pp. L465-L471 ◽  
Author(s):  
Alessandro Celi ◽  
Silvana Cianchetti ◽  
Stefano Petruzzelli ◽  
Stefano Carnevali ◽  
Filomena Baliva ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Airway Epithelial Cells ◽  
Bronchial Epithelial Cells ◽  
Neutrophil Adhesion ◽  
Late Time ◽  
Airway Epithelial ◽  
Bronchial Epithelial ◽  
Human Airway ◽  
Stimulation Of ◽  
Human Airway Epithelial Cells

Intercellular adhesion molecule-1 (ICAM-1) is the only inducible adhesion receptor for neutrophils identified in bronchial epithelial cells. We stimulated human airway epithelial cells with various agonists to evaluate whether ICAM-1-independent adhesion mechanisms could be elicited. Phorbol 12-myristate 13-acetate (PMA) stimulation of cells of the alveolar cell line A549 caused a rapid, significant increase in neutrophil adhesion from 11 ± 3 to 49 ± 7% (SE). A significant increase from 17 ± 4 to 39 ± 6% was also observed for neutrophil adhesion to PMA-stimulated human bronchial epithelial cells in primary culture. Although ICAM-1 expression was upregulated by PMA at late time points, it was not affected at 10 min when neutrophil adhesion was already clearly enhanced. Antibodies to ICAM-1 had no effect on neutrophil adhesion. In contrast, antibodies to the leukocyte integrin β-chain CD18 totally inhibited the adhesion of neutrophils to PMA-stimulated epithelial cells. These results demonstrate that PMA stimulation of human airway epithelial cells causes an increase in neutrophil adhesion that is not dependent on ICAM-1 upregulation.

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