P2-123: The deposition of Aß40 in the brain is pathognomonic for Alzheimer-type dementia in Down syndrome

2009 ◽  
Vol 5 (4S_Part_10) ◽  
pp. P297-P298 ◽  
Author(s):  
Pedro Pesini ◽  
Ana M. Lacosta ◽  
Manuel Sarasa
Keyword(s):  
Down Syndrome ◽  
Alzheimer Type ◽  
Alzheimer Type Dementia ◽  
The Brain

NORADRENALINE IN ALZHEIMER-TYPE DEMENTIA AND DOWN SYNDROME

The Lancet ◽  
1981 ◽  
Vol 318 (8236) ◽  
pp. 39-40 ◽  
Author(s):  
C.M. Yates ◽  
I.M. Ritchie ◽  
J. Simpson ◽  
A.F.J. Maloney ◽  
A. Gordon
Keyword(s):  
Down Syndrome ◽  
Alzheimer Type ◽  
Alzheimer Type Dementia

Classifying Organic Mental Disorders and Dementia—A Review of Historical Perspectives

1991 ◽  
Vol 3 (S1) ◽  
pp. 9-17 ◽  
Author(s):  
C. G. Gottfries
Keyword(s):  
Mental Disorders ◽  
Memory Impairment ◽  
Depressive Disorders ◽  
Alzheimer Type ◽  
Historical Perspectives ◽  
Alzheimer Type Dementia ◽  
Organic Mental Disorders ◽  
Icd 10 ◽  
Somatic Disorders ◽  
The Brain

The concept of dementia should not be used synonymously with the concept of organic mental disorders. By definition, according to DSM-III and ICD-10, dementia is a syndrome which includes memory impairment. The severity of the disorder is disabling and the course is chronic. Differential diagnosis includes age-associated memory impairment (AAMI), delirium, and depressive disorders. The dementias may be subdivided into four groups: idiopathic (primary degenerative dementias), vascular, secondary, and others. The idiopathic dementias are those in which etiology is assumed to be found within the brain itself. The main subgroup is Alzheimer-type dementia. The vascular dementias are those in which the blood supply to the brain is insufficient. Multi-infarct dementia (MID) is the prototype. In secondary dementias, somatic disorders either within or external to the brain cause the dementia.

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