IC-P-117: Characterization of regional cerebral blood flow in mild cognitive impairment and older adults with cognitive complaints

2013 ◽  
Vol 9 ◽  
pp. P71-P71 ◽  
Author(s):  
Yang Wang ◽  
John West ◽  
Shannon Risacher ◽  
Brenna McDonald ◽  
Eileen Tallman ◽  
...  
2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Teruyuki Matsuoka ◽  
Jin Narumoto ◽  
Keisuke Shibata ◽  
Aiko Okamura ◽  
Shogo Taniguchi ◽  
...  

The aim of this study was to examine the effect of toki-shakuyaku-san (TSS) on mild cognitive impairment (MCI) and Alzheimer's disease (AD) using single-photon emission computed tomography (SPECT). All subjects were administered TSS (7.5 g/day) for eight weeks. SPECT and evaluations using the Mini Mental State Examination (MMSE), Neuropsychiatric Inventory, and Physical Self-Maintenance Scale were performed before and after treatment with TSS. Three patients with MCI and five patients with AD completed the study. No adverse events occurred during the study period. After treatment with TSS, regional cerebral blood flow (rCBF) in the posterior cingulate was significantly higher than that before treatment. No brain region showed a significant decrease in rCBF. TSS treatment also tended to improve the score for orientation to place on the MMSE. These results suggest that TSS could be useful for treatment of MCI and AD.


2005 ◽  
Vol 1 ◽  
pp. S37-S38
Author(s):  
Fumio Yamashita ◽  
Kiyotaka Nemoto ◽  
Toru Kinoshita ◽  
Shin Hidata ◽  
Megumi Sasaki ◽  
...  

2008 ◽  
Vol 4 ◽  
pp. T383-T383
Author(s):  
Kyung Won Park ◽  
Ji Hye Kang ◽  
Sung-Kwan Kim ◽  
Do-Young Kang ◽  
Jae Woo Kim ◽  
...  

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