Preemptive Treatment of Phantom and Residual Limb Pain with Targeted Muscle Reinnervation at the Time of Major Limb Amputation

2019 ◽  
Vol 228 (3) ◽  
pp. 217-226 ◽  
Author(s):  
Ian L. Valerio ◽  
Gregory A. Dumanian ◽  
Sumanas W. Jordan ◽  
Lauren M. Mioton ◽  
J. Byers Bowen ◽  
...  
2018 ◽  
Author(s):  
Ian Valerio ◽  
Gregory A. Dumanian ◽  
Sumanas W. Jordan ◽  
Lauren M. Mioton ◽  
J. Byers Bowen ◽  
...  

2021 ◽  
Vol 4 (2) ◽  
Author(s):  
Emma-Leigh Rudduck ◽  
Frank Bruscino-Raiola ◽  
Margaret Angliss ◽  
Steven J Gray ◽  
David Lee Gow ◽  
...  

Targeted muscle reinnervation (TMR) reduces pain and physical and psychological disabilities in amputees. We present the first two cases reported globally of quadruple amputees that underwent acute TMR. Each patient completed our novel ‘The Alfred Hospital Osteointegration Survey’ (TAHOS) for each limb at six, 12 and 24 months post amputation which evaluated aspects of prosthesis wear, neuroma-related residual limb pain (RLP), phantom limb pain (PLP) and overall function. Our findings that TMR reduced or eliminated RLP and PLP by 12 months and clinically improved prosthetic function in both quadruple amputees reflects the current literature for single and multiple limb amputees.


2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Kevin Döring ◽  
Carmen Trost ◽  
Christoph Hofer ◽  
Martin Salzer ◽  
Tryphon Kelaridis ◽  
...  

2017 ◽  
Vol 41 (6) ◽  
pp. 601-604 ◽  
Author(s):  
Riemke GA de Boer ◽  
Marieke A Paping ◽  
Bert Kap ◽  
Jan HB Geertzen

Background:In all, 68% of all lower limb amputees experience residual limb pain. More than 95% of all lower limb amputations in developed countries are due to peripheral artery occlusive disease in combination with diabetes mellitus. Therefore, claudication, which is one of the most common manifestations of peripheral artery occlusive disease, should be taken into consideration in making a differential diagnosis of residual limb pain.Case description and methods:We present a case study of a 60-year-old diabetic patient who underwent a transfemoral amputation due to peripheral artery occlusive disease and who experiences residual limb pain. A computed tomography angiography was performed, and we searched for relevant literature on claudication pain after lower limb amputation.Conclusion:Little research has explored claudication as a cause of residual limb pain. More research will lead to a decrease in unnecessary prosthetic fittings and adjustments give more insight into the treatment and management of residual limb pain and prevent a decrease in mobility in amputees.Clinical relevanceClaudication due to peripheral artery occlusive disease should be included as a possible cause of residual limb pain to prevent unnecessary prosthetic fittings and adjustments and to minimize psychological effects and limitations in activities and participation.


2020 ◽  
Vol 8 ◽  
pp. 205031212095918
Author(s):  
Blair R Peters ◽  
Stephanie A Russo ◽  
Julie M West ◽  
Amy M Moore ◽  
Steven A Schulz

The life altering nature of major limb amputations may be further complicated by neuroma formation in up to 60% of the estimated 2 million major limb amputees in the United States. This can be a source of pain and functional limitation of the residual limb. Pain associated with neuromas may limit prosthetic limb use, require reoperation, lead to opioid dependence, and dramatically reduce quality of life. A number of management options have been described including excision alone, excision with repair, excision with transposition, and targeted muscle reinnervation. Targeted muscle reinnervation has been shown to reduce phantom limb and neuroma pain for patients with upper and lower extremity amputations. It may be performed at the time of initial amputation to prevent pain development or secondarily for the treatment of established pain. Encouraging outcomes have been reported, and targeted muscle reinnervation is emerging as a leading surgical technique for pain prevention in patients undergoing major limb amputations and pain management in patients with pre-existing amputations.


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