A functional and bilateral ischiofemoral impingement with muscular hypertrophy in an 11-year-old dancer

2021 ◽  
pp. 105251
Author(s):  
Pauline Nougues ◽  
Mathieu Le Strat ◽  
Florent Garrigues ◽  
Dewi Guellec ◽  
Alain Saraux ◽  
...  
1978 ◽  
Vol 46 (5) ◽  
pp. 1201-1205 ◽  
Author(s):  
F. D. Carroll ◽  
R. B. Thiessen ◽  
W. C. Rollins ◽  
N. C. Powers
Keyword(s):  

2018 ◽  
Vol 7 (4) ◽  
pp. e321-e325 ◽  
Author(s):  
Rafael Corrales ◽  
Iñaki Mediavilla ◽  
Eric Margalet ◽  
Mikel Aramberri ◽  
Jorge A. Murillo-González ◽  
...  

1952 ◽  
Vol 43 (2) ◽  
pp. 63-68 ◽  
Author(s):  
J. F. KIDWELL ◽  
E. H. VERNON ◽  
R. M. CROWN ◽  
C. B. SINGLETARLY
Keyword(s):  

2015 ◽  
Vol 44 (12) ◽  
pp. 1755-1760 ◽  
Author(s):  
Adriana L. Oliveira ◽  
Debora C. Azevedo ◽  
Alireza Eajazi ◽  
William E. Palmer ◽  
Young-Min Kwon ◽  
...  

1870 ◽  
Vol 16 (73) ◽  
pp. 46-52
Author(s):  
Langdon Down

Reviewing a large number of cases of idiocy and imbecility which have come under my observation, I am able to call prominently to mind three cases in which apparent hypertrophy of muscle, combined with motor paralysis, was present. As these occurred to me before Dr. Duchenne, of Bologne, had pointed out their significance, I did not take steps to verify their condition. So marked, however, was the apparent muscular development, that the muscular feebleness puzzled me much. Faradization was tried in one case without any good result.


2017 ◽  
Vol 9 (4) ◽  
pp. 529 ◽  
Author(s):  
Alejandro Hernandez ◽  
Sleiman Haddad ◽  
Jorge H. Nuñez ◽  
Albert Gargallo-Margarit ◽  
Andrea Sallent ◽  
...  

2010 ◽  
Vol 2010 ◽  
pp. 1-8 ◽  
Author(s):  
Kunihiro Sakuma ◽  
Akihiko Yamaguchi

Skeletal muscle uses calcium as a second messenger to respond and adapt to environmental stimuli. Elevations in intracellular calcium levels activate calcineurin, a serine/threonine phosphatase, resulting in the expression of a set of genes involved in the maintenance, growth, and remodeling of skeletal muscle. In this review, we discuss the effects of calcineurin activity on hypertrophy, regeneration, and disorders of skeletal muscle. Calcineurin is a potent regulator of muscle remodeling, enhancing the differentiation through upregulation of myogenin or MEF2A and downregulation of the Id1 family and myostatin. Foxo may also be a downstream candidate for a calcineurin signaling molecule during muscle regeneration. The strategy of controlling the amount of calcineurin may be effective for the treatment of muscular disorders such as DMD, UCMD, and LGMD. Activation of calcineurin produces muscular hypertrophy of the slow-twitch soleus muscle but not fast-twitch muscles.


Author(s):  
Shotaro Murata ◽  
Takashi Sasaki ◽  
Yuki Yamauchi ◽  
Makoto Shimizu ◽  
Ryuichiro Sato

ABSTRACT Maslinic acid, a naturally occurring pentacyclic triterpene in more than 30 plants (including olives), reportedly increases human muscle mass and muscle strength; however, the underlying molecular mechanism remains unknown. C57BL/6J mice were fed a standard diet or supplemented with 0.27% maslinic acid for 4 weeks, and their skeletal muscle mass was measured. Mice that consumed maslinic acid displayed significant increases in gastrocnemius and soleus muscle mass. Cultured mouse-C2C12 skeletal muscle cells were treated with mammalian target of rapamycin complex 1 (mTORC1) or protein kinase b (Akt) inhibitor, and protein synthesis was quantified. Maslinic acid accelerated protein synthesis via mTORC1 activation independent of Akt. Furthermore, maslinic acid activated human Takeda G protein-coupled receptor 5 (TGR5) more strongly than mouse TGR5, augmenting the expression of several genes related to muscular hypertrophy. Maslinic acid activated mTORC1 and human TGR5, implying its contribution to human muscular hypertrophy through these effects.


2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Hugo C. Martins-Costa ◽  
Lucas T. Lacerda ◽  
Rodrigo C.R. Diniz ◽  
Fernando V. Lima ◽  
André G. P. Andrade ◽  
...  

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