Development and validation of a liquid chromatography/mass spectrometry method for pharmacokinetic studies of OZ78, a fasciocidal drug candidate

2010 ◽  
Vol 878 (28) ◽  
pp. 2770-2774 ◽  
Author(s):  
Carla Kirchhofer ◽  
Jennifer Keiser ◽  
Jörg Huwyler
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Drug Candidate ◽  
Pharmacokinetic Studies ◽  
Liquid Chromatography Mass Spectrometry ◽  
Spectrometry Method ◽  
Mass Spectrometry Method ◽  
Chromatography Mass Spectrometry ◽  
Development And Validation

A validated liquid chromatography mass spectrometry method for the quantification of tinoridine hydrochloride in rat plasma and its application to pharmacokinetic studies

2015 ◽  
Vol 7 (5) ◽  
pp. 1965-1970 ◽  
Author(s):  
Pradipbhai D. Kalariya ◽  
Prinesh N. Patel ◽  
Challa Veerabhadra Swamy ◽  
R. Srinivas ◽  
M. V. N. Kumar Talluri
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Rat Plasma ◽  
Pharmacokinetic Studies ◽  
Liquid Chromatography Mass Spectrometry ◽  
Spectrometry Method ◽  
Mass Spectrometry Method ◽  
Chromatography Mass Spectrometry ◽  
Fast Liquid Chromatography

A selective, sensitive and fast liquid chromatography coupled with mass spectrometry method (LC-MS) has been developed and validated for the quantification of tinoridine hydrochloride in rat plasma.

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