Primary effusion lymphoma with cardiac involvement in HIV positive patient—Complete response and long survival with chemotherapy and HAART

2009 ◽  
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Paula Yurie Tanaka ◽  
Magda Maya Atala ◽  
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Adele Caterino-de-Araujo
2009 ◽  
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1988 ◽  
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Hanan Farghaly ◽  
Rafael Perez ◽  
Forest W Arnold

2014 ◽  
Vol 2014 (oct13 1) ◽  
pp. bcr2014204533-bcr2014204533 ◽  
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J. Carvalho ◽  
C. Patricio ◽  
P. Farinha

2018 ◽  
Vol 2018 ◽  
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Hamza Hashmi ◽  
Drew Murray ◽  
Samer Al-Quran ◽  
William Tse

Primary effusion lymphoma (PEL) is a unique form of non-Hodgkin lymphoma, usually seen in severely immunocompromised, HIV-positive patients. PEL is related to human herpesvirus-8 (HHV-8) infection, and it usually presents as a lymphomatous body cavity effusion in the absence of a solid tumor mass. There have been very few case reports of HIV-positive patients with HHV-8-positive solid tissue lymphomas not associated with an effusion (a solid variant of PEL). In the absence of effusion, establishing an accurate diagnosis can be challenging, and a careful review of morphology, immunophenotype, and presence of HHV-8 is necessary to differentiate from other subtypes of non-Hodgkin lymphoma. Treatment involves intensive chemotherapy, and prognosis is usually poor. We present a rare case of a PEL variant in an HIV-positive patient who presented with extensive lymphadenopathy without any associated effusions.


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