scholarly journals Redox-active biflavonoids from Garcinia brasiliensis as inhibitors of neutrophil oxidative burst and human erythrocyte membrane damage

2015 ◽  
Vol 174 ◽  
pp. 410-418 ◽  
Author(s):  
Phanuel Saroni Arwa ◽  
Maria Luiza Zeraik ◽  
Valdecir Farias Ximenes ◽  
Luiz Marcos da Fonseca ◽  
Vanderlan da Silva Bolzani ◽  
...  
1995 ◽  
Vol 2 (2) ◽  
pp. 73-80 ◽  
Author(s):  
J.-F. Lu ◽  
K. Wang ◽  
X.-Z. Sun ◽  
F. Xing ◽  
P.-D. An ◽  
...  

The biomembrane is postulated as the initial target when Platinum(II) complexes attack cells. In this work, a spin-labeling ESR technique has been used to study the effects of cis-DCDP, cis-DBDP, cis-DIDP, trans-DCDP, and cis-DADP on the permeability of human erythrocyte membrane. We monitored the reduction processes of the ESR signal of a nitroxide spin label, (TEMPO), which leaks out through the membrane and is reduced by the external ascorbate. Our results indicate that cisplatin and its analogues can enhance the permeability of membranes to small moieties such as TEMPO and ascorbate, and the differences between these compounds are related to features of the leaving group. In addition, changes in the order parameter of 5DS spin label in membrane indicate that hydrolysis of these Pt(II) complexes result in membrane damage.


1974 ◽  
Vol 249 (4) ◽  
pp. 1022-1025
Author(s):  
Klaus Stellner ◽  
Sen-Itiroh Hakomori

1970 ◽  
Vol 12 (1) ◽  
pp. 65-65
Author(s):  
Yuko Yamada ◽  
Hisashi Yamada ◽  
Minoru Hamada

1990 ◽  
Vol 168 (2) ◽  
pp. 651-658 ◽  
Author(s):  
P. Nassi ◽  
C. Nediani ◽  
G. Liguri ◽  
N. Taddei ◽  
M. Ruggiero ◽  
...  

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