Comparison of the Odontogenic Differentiation Potential of Dental Follicle, Dental Papilla, and Cranial Neural Crest Cells

2015 ◽  
Vol 41 (7) ◽  
pp. 1091-1099 ◽  
Author(s):  
Gang Chen ◽  
Qince Sun ◽  
Li Xie ◽  
Zongting Jiang ◽  
Lian Feng ◽  
...  
Keyword(s):  
Neural Crest ◽  
Neural Crest Cells ◽  
Dental Follicle ◽  
Cranial Neural Crest ◽  
Differentiation Potential ◽  
Dental Papilla ◽  
Odontogenic Differentiation ◽  
Cranial Neural Crest Cells

scholarly journals Reactivation of the pluripotency program precedes formation of the cranial neural crest

Science ◽  
2021 ◽  
Vol 371 (6529) ◽  
pp. eabb4776 ◽  
Author(s):  
Antoine Zalc ◽  
Rahul Sinha ◽  
Gunsagar S. Gulati ◽  
Daniel J. Wesche ◽  
Patrycja Daszczuk ◽  
...  
Keyword(s):  
Neural Crest ◽  
Craniofacial Development ◽  
Open Chromatin ◽  
Cranial Neural Crest ◽  
Craniofacial Skeleton ◽  
Differentiation Potential ◽  
Subsequent Formation ◽  
Developmental Potential ◽  
Epiblast Stem Cells ◽  
Cranial Neural Crest Cells

During development, cells progress from a pluripotent state to a more restricted fate within a particular germ layer. However, cranial neural crest cells (CNCCs), a transient cell population that generates most of the craniofacial skeleton, have much broader differentiation potential than their ectodermal lineage of origin. Here, we identify a neuroepithelial precursor population characterized by expression of canonical pluripotency transcription factors that gives rise to CNCCs and is essential for craniofacial development. Pluripotency factor Oct4 is transiently reactivated in CNCCs and is required for the subsequent formation of ectomesenchyme. Furthermore, open chromatin landscapes of Oct4+ CNCC precursors resemble those of epiblast stem cells, with additional features suggestive of priming for mesenchymal programs. We propose that CNCCs expand their developmental potential through a transient reacquisition of molecular signatures of pluripotency.

Laser capture microdissection of fluorescently labeled embryonic cranial neural crest cells

genesis ◽  
2004 ◽  
Vol 39 (1) ◽  
pp. 58-64 ◽  
Author(s):  
Vasker Bhattacherjee ◽  
Partha Mukhopadhyay ◽  
Saurabh Singh ◽  
Emily A. Roberts ◽  
Rita C. Hackmiller ◽  
...  
Keyword(s):  
Neural Crest ◽  
Laser Capture Microdissection ◽  
Neural Crest Cells ◽  
Cranial Neural Crest ◽  
Cranial Neural Crest Cells ◽  
Laser Capture

scholarly journals Cranial neural crest cells on the move: Their roles in craniofacial development

2010 ◽  
Vol 155 (2) ◽  
pp. 270-279 ◽  
Author(s):  
Dwight R. Cordero ◽  
Samantha Brugmann ◽  
Yvonne Chu ◽  
Ruchi Bajpai ◽  
Maryam Jame ◽  
...  
Keyword(s):  
Neural Crest ◽  
Neural Crest Cells ◽  
Craniofacial Development ◽  
Cranial Neural Crest ◽  
Cranial Neural Crest Cells
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