Resolution of Oral Bisphosphonate and Steroid-Related Osteonecrosis of the Jaw—A Serial Case Analysis

2010 ◽  
Vol 68 (5) ◽  
pp. 1055-1063 ◽  
Author(s):  
Chang-Ta Chiu ◽  
Wei-Fan Chiang ◽  
Ching-Ya Chuang ◽  
Sung-Wen Chang
2021 ◽  
Vol 11 ◽  
Author(s):  
Marília A. Figueiredo ◽  
Frederico Buhatem Medeiros ◽  
Karem López Ortega

2018 ◽  
Vol 44 (5) ◽  
pp. 359-364
Author(s):  
Shinsuke Yamamoto ◽  
Keigo Maeda ◽  
Izumi Kouchi ◽  
Yuzo Hirai ◽  
Naoki Taniike ◽  
...  

Dental implant treatment is a highly predictable therapy, but when potentially lethal symptoms or complications occur, dentists must remove the implant fixture. Recently, reports on antiresorptive agent-related osteonecrosis of the jaw have increased in the field of dental implants, although the relationship between dental implant treatment and antiresorptive agents remains unclear. Here, we report a case of antiresorptive agent-related osteonecrosis of the jaw that developed after dental implant removal. A 67-year-old Japanese woman with a medical history of osteoporosis and 7 years of oral bisphosphonate treatment was referred to our hospital with a chief complaint of painful right mandibular bone exposure. A family dentist removed the dental implants from the right mandible using a trephine drill without flap elevation in August 2016. However, the healing was impaired; she was referred to our hospital 3 months after the procedure. We performed a sequestrectomy of the mandible under general anesthesia. In conclusion, this patient's course has two important implications: First, the removal of dental implants from patients who are prescribed oral bisphosphonates for long durations can cause antiresorptive agent-related osteonecrosis of the jaw. Second, meticulous procedures are required to prevent and treat the development of antiresorptive agent-related osteonecrosis of the jaw after dental implant removal.


2018 ◽  
Vol 23 (1) ◽  
pp. 83-89 ◽  
Author(s):  
David Steybe ◽  
Pit Jacob Voss ◽  
Michael Andreas Ermer ◽  
Marc Anton Fuessinger ◽  
Rainer Schmelzeisen ◽  
...  

2009 ◽  
Vol 140 (1) ◽  
pp. 61-66 ◽  
Author(s):  
Parish P. Sedghizadeh ◽  
Kyle Stanley ◽  
Matthew Caligiuri ◽  
Shawn Hofkes ◽  
Brad Lowry ◽  
...  

RSBO ◽  
2017 ◽  
Vol 14 (2) ◽  
pp. 98-105
Author(s):  
Paola Fernanda Cotait de Lucas Corso ◽  
Sara Regina Todero ◽  
Aline Monise Sebastiani ◽  
Leandro Eduardo Kluppel ◽  
Nelson Luis Barbosa Rebellato ◽  
...  

Osteonecrosis of the jaw is associated with defects in vascularization and with the use of oral bisphosphonates. Osseous exposition and infection may occur. Recommended treatment is variable, from antibiotic medication, bony decortication to resections of the mandible in severe cases. Reconstruction of mandible, in cases of resections is essential for maintaining esthetic profile and adequate form and function. Objective: To report a case about the dangers of oral bisphosphonates in association with invasive procedures such as dental implants Case report: Female patient, 64 years-old, with osteonecrosis of the jaw caused by use of oral bisphosphonates after rehabilitation with dental implants. She had an edentulous and atrophic mandible and poor healthy. After diagnosis, partial resection of the jaw was performed together with the reconstruction with titanium plate, with no success. Then, iliac bone graft fixed by plates and screws was attempted, again with no success. Conclusion: Despite of the small number of cases of osteonecrosis associated with oral bisphosphonate reported in the literature, a simple implant surgery could result in adverse consequences if the use of this medication were overlooked in the anamnesis.


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