Fetus-in-Fetu: A Case of Ovarian Involvement and Residual Re-growth in a Teenager

Abstract Background Fetus in fetu is a rare congenital anomaly. The exact etiology is unclear; one of the mostly accepted theories is the occurrence of an embryological insult occurring in a diamniotic monochorionic twin leading to asymmetrical division of the blastocyst mass. Commonly, they present in the infancy with clinical picture related to their mass effect. About 80% of cases are in the abdomen retroperitoneally. Case presentation We present two cases of this rare condition. The first case was for a 10-year-old girl that presented with anemia and abdominal mass, while the second case was for a 4-month-old boy that was diagnosed antenatally by ultrasound. Both cases had vertebrae, recognizable fetal organs, and skin coverage. Both had a distinct sac. The second case had a vascular connection with the host arising from the superior mesenteric artery. Both cases were intra-abdominal and showed normal levels of alpha-fetoprotein. Histopathological examination revealed elements from the three germ layers without any evidence of immature cells ruling out teratoma as a differential diagnosis. Conclusions Owing to its rarity, fetus in fetu requires a high degree of suspicion and meticulous surgical techniques to avoid either injury of the adjacent vital structures or bleeding from the main blood supply connection to the host. It should be differentiated from mature teratoma.

Download Full-text

Clinical features and prognostic relevance of ovarian involvement in non-Hodgkin's lymphoma: A Consortium for Improving Survival of Lymphoma (CISL) report

Leukemia Research ◽

10.1016/j.leukres.2010.02.010 ◽

2010 ◽

Vol 34 (9) ◽

pp. 1175-1179 ◽

Cited By ~ 17

Author(s):

Jina Yun ◽

Seok Jin Kim ◽

Jong Ho Won ◽

Chul Won Choi ◽

Hyeon Seok Eom ◽

...

Keyword(s):

Clinical Features ◽

Hodgkin’S Lymphoma ◽

Hodgkin's Lymphoma ◽

Prognostic Relevance ◽

Non Hodgkin’S Lymphoma ◽

Non Hodgkin's Lymphoma ◽

Ovarian Involvement

Download Full-text

Chromosomal anomalies that cause male sterility in the mouse also reduce ovary size

Genetics Research ◽

10.1017/s0016672300026409 ◽

1984 ◽

Vol 44 (2) ◽

pp. 219-224 ◽

Cited By ~ 10

Author(s):

Ursula Mittwoch ◽

Shantha Mahadevaiah ◽

Leslie A. Setterfield

Keyword(s):

Male Sterility ◽

Germ Cells ◽

Reciprocal Translocation ◽

Chromosomal Anomalies ◽

Male Sterile ◽

Chromosome Anomalies ◽

Ovarian Size ◽

Males And Females ◽

The Difference ◽

Ovarian Involvement

SUMMARYTwo male-sterile chromosome anomalies, the insertion Is(7; 1)40H and the tertiary trisomy, Ts(512)31H, were found to be associated with reduced ovarian volumes in immature females. Together with the reciprocal translocation, T(11; 19)42H, in which this effect was described previously, reduced ovaries have been found in all three male-sterile chromosome anomalies investigated so far, suggesting that ovarian involvement is likely to be common in these conditions. Assuming that the smaller ovarian size reflects a reduction in the number of oocytes, it is suggested that male-sterile chromosome anomalies may exert basically similar deleterious effects on meiotic germ cells in males and females, the difference in outcome being due to cell-physiological differences between spermatocytes and oocytes and to the small number of surviving oocytes required for fertility in females.

Download Full-text