scholarly journals Fetus in fetu: two case reports from North African country

2021 ◽  
Vol 69 (1) ◽  
Author(s):  
Moutaz Ragab ◽  
Omar Nagy Abdelhakeem ◽  
Omar Mansour ◽  
Mai Gad ◽  
Hesham Anwar Hussein
Keyword(s):  
Histopathological Examination ◽  
Case Reports ◽  
Abdominal Mass ◽  
Mature Teratoma ◽  
Surgical Techniques ◽  
Rare Condition ◽  
Mass Effect ◽  
Fetus In Fetu ◽  
Vascular Connection ◽  
First Case

Abstract Background Fetus in fetu is a rare congenital anomaly. The exact etiology is unclear; one of the mostly accepted theories is the occurrence of an embryological insult occurring in a diamniotic monochorionic twin leading to asymmetrical division of the blastocyst mass. Commonly, they present in the infancy with clinical picture related to their mass effect. About 80% of cases are in the abdomen retroperitoneally. Case presentation We present two cases of this rare condition. The first case was for a 10-year-old girl that presented with anemia and abdominal mass, while the second case was for a 4-month-old boy that was diagnosed antenatally by ultrasound. Both cases had vertebrae, recognizable fetal organs, and skin coverage. Both had a distinct sac. The second case had a vascular connection with the host arising from the superior mesenteric artery. Both cases were intra-abdominal and showed normal levels of alpha-fetoprotein. Histopathological examination revealed elements from the three germ layers without any evidence of immature cells ruling out teratoma as a differential diagnosis. Conclusions Owing to its rarity, fetus in fetu requires a high degree of suspicion and meticulous surgical techniques to avoid either injury of the adjacent vital structures or bleeding from the main blood supply connection to the host. It should be differentiated from mature teratoma.

scholarly journals Fetus in fetu in an adult woman

2019 ◽  
Vol 12 (8) ◽  
pp. e230835 ◽  
Author(s):  
Anil Kumar ◽  
Shiv Shankar Paswan ◽  
Bindey Kumar ◽  
Prem Kumar
Keyword(s):  
Histopathological Examination ◽  
Rare Condition ◽  
Surgical Excision ◽  
Exploratory Laparotomy ◽  
Late Presentation ◽  
Adult Woman ◽  
Suspected Case ◽  
Fetus In Fetu ◽  
First Case ◽  
The Ideal

Fetus in fetu (FIF) is an extremely rare condition in which malformed fetus is found most commonly in the retroperitoneum of living twin. It occurs in about 1 in 500 000 live births and less than 200 cases have been reported in medical literature. We report FIF in a 17-year-old woman unlike other cases which were usually detected in early age and in male gender. This is the eighth case of adult FIF and the first case of FIF in adult woman worldwide. Preoperative diagnosis of FIF on CT was made and planned for exploratory laparotomy. The excised malformed fetus in a sac was proven as FIF on the basis of histopathological examination. In view to avoid such late presentation, early detection of FIF with radiological imaging in clinically suspected case is recommended. Surgical excision is the ideal treatment even teratoma is the differential diagnosis.

scholarly journals Alternative Leprosy Treatment Using Rifampicin Ofloxacin Minocycline (ROM) Regimen – Two Case Reports

2019 ◽  
Vol 11 (3) ◽  
pp. 89-93
Author(s):  
Yohanes Widjaja ◽  
Khairuddin Djawad ◽  
Saffruddin Amin ◽  
Widyawati Djamaluddin ◽  
Dirmawati Kadir ◽  
...  
Keyword(s):  
Clinical Improvement ◽  
Alternative Treatment ◽  
Histopathological Examination ◽  
Case Reports ◽  
Erythematous Plaque ◽  
First Case ◽  
Satisfactory Outcome ◽  
Significant Clinical Improvement ◽  
The Right

Abstract Introduction. Leprosy is a disease that predominantly affects the skin and peripheral nerves, resulting in neuropathy and associated long-term consequences, including deformities and disabilities. According to the WHO classification, there are two categories of leprosy, paucibacillary (PB) and multibacillary (MB). The standard treatment for leprosy employs the use of WHO MDT (Multi Drug Treatment) regimen, despite its multiple downsides such as clofazimine-induced pigmentation, dapsone-induced haematological adverse effects, poor compliance due to long therapy duration, drug resistance, and relapse. Multiple studies and case reports using ROM regimen have reported satisfactory results. Nevertheless, there are still insufficient data to elucidate the optimum dosage and duration of ROM regimen as an alternative treatment for leprosy. Previous experience from our institution revealed that ROM regimen given three times weekly resulted in a satisfactory outcome. Case Reports. We report two cases of leprosy treated with ROM regimen from our institution. The first case was PB leprosy in a 64-year-old male who presented with a single scaly plaque with erythematous edge on the right popliteal fossa. Sensibility examination showed hypoesthesia with no peripheral nerve enlargement. Histopathological examination confirmed Borderline Tuberculoid leprosy. ROM regimen was started three times weekly for 6 weeks and the patient showed significant clinical improvement at the end of the treatment with no reaction or relapse until after 6 months after treatment. The second case was MB leprosy in a 24-year-old male patient with clawed hand on the 3rd-5th phalanges of the right hand and a hypoesthetic erythematous plaque on the forehead. Histopathology examination confirmed Borderline leprosy. The patients received ROM therapy 3 times a week with significant clinical improvement after 12 weeks. Conclusion. ROM regimen given three times weekly for 6 weeks in PB leprosy and 12 weeks in MB leprosy resulted in a significant clinical improvement. Thus, ROM regimen could be a more effective, safer, faster alternative treatment for leprosy.

scholarly journals Operation procedure of sacrococcygeal fetus in fetu

2011 ◽  
Vol 51 (1) ◽  
pp. 58 ◽  
Author(s):  
Rochadi Rochadi
Keyword(s):  
Adrenal Gland ◽  
Abdominal Mass ◽  
Rare Condition ◽  
Mature Embryo ◽  
First Year ◽  
Fetus In Fetu ◽  
Sacrococcygeal Region ◽  
Parasitic Twin ◽  
Operation Procedure ◽  
First Year Of Life

Fetus in fetu is a condition in wich a fetiform calcified mass often presents in the abdomen of its host, a newborn. It is extremely rare condition, estimated once in 500,000 deliveries and has a 2: 1 male predominantly; with most patient presenting with an abdominal  mass in the first year of life. 5,13 The term fetus in fetu is used to point out an unequal division of totipotential cells of blastocyst where the result is the inclusion of a small cellular mass in the more mature embryo. It was encapsulated, pedunculated and represents a malformed monozygotic, monochorionic, diamniotic parasitic twin. In 80% cases, fetus in fetu is located  retroperitonealy but can be found in unusual location such as in oropharynx, neck, skull mediastinum, pelvis, iliac mesentery, adrenal gland, sacrococcygeal region and scrotal sac.

scholarly journals Lipoleiomyosarcoma an extremely unusual sarcoma of uterus: A case report

1970 ◽  
Vol 2 (1) ◽  
pp. 67-70 ◽  
Author(s):  
Abhimanyu Jha ◽  
Gita Sayami ◽  
Deepti Adhikari
Keyword(s):  
Smooth Muscle ◽  
Abdominal Pain ◽  
Case Report ◽  
Postmenopausal Woman ◽  
Unusual Case ◽  
Histopathological Examination ◽  
Abdominal Mass ◽  
Lower Abdominal Pain ◽  
First Case ◽  
Well Differentiated

Uterine lipoleiomyosarcoma is a heterologous sarcoma composed of variable proportions of malignant lipoblasts histologically corresponding to well differentiated liposarcoma and malignant smooth muscle cells corresponding to leiomyosarcoma. Finding of benign lipomatous component in a typical leiomyoma (lipoleiomyoma) is not an uncommon, however, lipoleiomyosarcoma is an extremely rare malignant tumor and only very few cases have been reported so far. We report a case of lipoleiomyosarcoma of uterine corpus in a postmenopausal woman presenting with lower abdominal pain and abdominal mass. Diagnosis of lipoleiomyosarcoma was confirmed by histopathological examination of hysterectomy specimen. This is the first case of lipoleiomyosarcoma of uterus reported from Nepal. Keywords: Lipoleiomyosarcoma, uterus, histopathology, unusual case.   doi:10.3126/njog.v2i1.1482    N. J. Obstet. Gynaecol Vol. 2, No. 1, p. 67 - 70 May -June 2007

scholarly journals Two Neonates with Congenital Hydrocolpos

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Vydehi Murthy ◽  
Jessica Costalez ◽  
Julie Weiner ◽  
Kristin Voos
Keyword(s):  
Prenatal Diagnosis ◽  
Reproductive Tract ◽  
Abdominal Mass ◽  
Rare Condition ◽  
Mass Effect ◽  
Cystic Mass ◽  
Sacrococcygeal Teratoma ◽  
Mri Imaging ◽  
Fetal Diagnosis ◽  
High Index Of Suspicion

Introduction. Neonatal hydrocolpos is a rare condition. Hydrocolpos is cystic dilatation of the vagina with fluid accumulation due to a combination of stimulation of secretary glands of the reproductive tract and vaginal obstruction. The differential for a neonatal presentation of lower abdominal mass includes urogenital anomalies, Hirschsprung’s, disease or sacrococcygeal teratoma. Prenatal diagnosis and early newborn imaging studies leads to early detection and treatment of these cases.Case. We report here two cases of neonatal hydrocolpos with prenatal diagnosis of lower abdominal mass. Postnatally, ultrasound, MRI imaging, and cystoscopy confirmed large cystic mass as hydrocolpos with distal vaginal obstruction. Both patients had enlarged renal system secondary to mass effect.Conclusion. High index of suspicion for hydrocolpos in a newborn presenting with fetal diagnosis of infraumbilical abdominal mass will facilitate timely intervention and prevention of complications.

scholarly journals Struma ovarii: two case reports of a rare teratoma of the ovary

2020 ◽  
Vol 2020 (12) ◽  
Author(s):  
Obed Rockson ◽  
Christine Kora ◽  
Abdelbassir Ramdani ◽  
Aabdi Basma ◽  
Tariq Bouhout ◽  
...  
Keyword(s):  
Histopathological Examination ◽  
Case Reports ◽  
Thyroid Tissue ◽  
Ovarian Teratoma ◽  
Histopathological Study ◽  
Histopathological Diagnosis ◽  
Struma Ovarii ◽  
Rare Type ◽  
Benign Condition ◽  
First Case

Abstract Struma ovarii is an extremely rare type of ovarian teratoma distinguished by the unusual presence of thyroid tissue. It is usually a benign condition; however, malignant transformation is sometimes detected. The diagnosis relies on histopathological examination and is infrequently made on routine investigations. We report two cases of struma ovarii: one benign and the other malignant. The first case involved a 27-year-old woman who underwent a right ovarian cystectomy for an incidental ultrasonographic finding of a solid right adnexal mass. The diagnosis of a benign struma was made after histopathological study. The second case involved a 68-year-old woman who underwent a right salpingo-oophorectomy for a right ovarian bulky mass and the histopathological diagnosis was consistent with that of a malignant struma. We examine the challenges involved in the diagnosis and management of this rare entity.

scholarly journals Fetus-in-fetu in an 8-month-old girl

2016 ◽  
Author(s):  
Bei Bei Zhao ◽  
Yu Zuo Bai
Keyword(s):  
Abdominal Mass ◽  
Mature Teratoma ◽  
Abdominal Distension ◽  
Axial Skeleton ◽  
Definitive Diagnosis ◽  
Pathological Examination ◽  
Cranial Cavity ◽  
Fetus In Fetu ◽  
Live Births ◽  
Sacrococcygeal Region

Fetus in fetu (FIF) is a very rare congenital malformation with an incidence of 1/500,000 live births. These children are often hospitalized because of vomiting, abdominal distension or abdominal mass found by their parents. The most common position for the parasitic fetus is the retroperitoneum but other position such as the scrotal sac, cranial cavity, sacrococcygeal region, back , oral cavity has been reported. FIF is often misdiagnosed as a mature teratoma. Ultrasound, CT, MRI are of great significance in distinguishing between FIF and teratoma. The postoperative pathological examination may reveal axial skeleton which can make a definitive diagnosis of FIF. In this report, we present a case of FIF in an 8-month-old girl.

scholarly journals Gastrosplenic Fistula Due to Splenic Lymphoma: Two Case Reports and Literature Review

2021 ◽  
Author(s):  
Feryel Ksontini Letaief ◽  
Issaad Nefzi ◽  
salim khrouf ◽  
Sonia ouali ◽  
Asma Zidi ◽  
...  
Keyword(s):  
Case Reports ◽  
Splenic Abscess ◽  
Rare Condition ◽  
B Cell Lymphoma ◽  
Review Literature ◽  
Treatment Modalities ◽  
Large B Cell Lymphoma ◽  
First Case ◽  
Splenic Lymphoma ◽  
Dangerous Condition

Abstract PurposeGastrosplenic fistula (GSF) is a rare and potentially fatal complication of various diseases, of which lymphoma is the most common cause. We aim through our work to relate two cases of GSF and to review literature. Methods We reviewed two cases treated in our department of GSF and made a research in Pubmed using the keywords “Gastrosplenic fistula” and “Splenic lymphoma”.Results GSF is a rare condition that can occur spontaneously or after initiation of chemotherapy. It arises from the rapid growth of tumour and invasion of surrounding organs. Diagnosis may be difficult to make and confused with splenic abscess. Treatment modalities include surgical resection, chemotherapy or a combination of both. Here we report two cases of GSF due to diffuse large B cell lymphoma patients. The first case is of a 54-year-old woman with a spontaneous fistula in the stomach. The second one is of a 48 year-old- male patient presenting a fistula after chemotherapy. Both patients died after surgery. ConclusionGSF is a rare but dangerous condition in which surgery is currently the preferred treatment.

scholarly journals Neuroendocrine tumor of appendix located Spiegel hernia – case report and review of the literature

2021 ◽  
Vol 19 (3) ◽  
pp. 270-272
Author(s):  
Furkan Karahan ◽  
◽  
Arif Atay ◽  
Neşe Ekinci ◽  
Emine Özlem Gür ◽  
...  
Keyword(s):  
Neuroendocrine Tumor ◽  
Histopathological Examination ◽  
Rare Condition ◽  
Definitive Diagnosis ◽  
Review Of The Literature ◽  
Incarcerated Hernia ◽  
Hernia Sac ◽  
First Case ◽  
Asymptomatic Patients ◽  
Well Differentiated

Introduction. Appendix, located within the Spiegel hernia is a rare condition. Few cases have been reported to date. Although it is generally asymptomatic, patients can apply with strangulation findings. Along with the physical examination findings, imaging methods play an important role in diagnosis and definitive diagnosis is made intraoperatively. Per-operative surgical method is determined according to the condition of the structures in the hernia sac. If an appendix is detected in the hernia sac, appendectomy is often preferred regardless of symptoms. Postoperative pathology is mostly benign but malign appendix pathologies should be kept in mind. Aim. Here, we aimed to present our case undergoing emergency surgery due to incarcerated hernia as it is the first case of appendix neuroendocrine tumor in the Spiegel hernia sac according to our literature review. Description of the case. A 77-year-old female patient who was admitted to the hospital with complaints of nausea and vomiting was evaluated as an emergency. In the clinical evaluation of the patient, we detected ileus due to hernia. We operated on the patient and found the appendix and cecum in the spiegel hernia. We did appendectomy and hernia repair. Histopathological examination of the appendix revealed a well-differentiated neuroendocrine tumor. Conclusion. Detection of the appendix in a Spiegel hernia is a rare condition. This is the first case of appendiceal malignancy in a Spiegelian hernia.

Erythrocytosis and Normal Erythropoietin Levels In a 3 Year Old Female With High-Risk Neuroblastoma

Blood ◽  
2013 ◽  
Vol 122 (21) ◽  
pp. 4664-4664
Author(s):  
Erin Kelly Barr ◽  
Mary Elizabeth Ross ◽  
Mohamad M. Al-Rahawan
Keyword(s):  
High Risk ◽  
Pediatric Patient ◽  
Conflicts Of Interest ◽  
Case Reports ◽  
Abdominal Mass ◽  
Tumor Resection ◽  
Neuroblastoma Cells ◽  
Hemoglobin Level ◽  
Age Group ◽  
First Case

Introduction Erythrocytosis has been reported in a number of cancers as a result of tumor production of Erythropoietin (EPO). There has been one reported case that we are aware of in a pediatric patient with neuroblastoma (Wang LY, et al. J Pediatr Hematol Oncol. 2003 Aug;25(8):649-50). Erythrocytosis in a pediatric neuroblasotoma patient with normal EPO levels, which is the subject of this case report, has not been reported previously. Case A three year-old female presented with a right sided abdominal pain of one week duration as well as constipation and decreased appetite of one month duration. Radiology studies showed a large abdominal mass, which turned out to be a poorly differentiated high-risk neuroblastoma on an incisional biopsy. For the first three months of this patient’s therapy and despite intense chemotherapy she was noted to have abnormally high hemoglobin levels. The peak hemoglobin level was 18 g/dL but she maintained hemoglobin levels greater than 14g/dL, which was greater than the 97th percentile for her age group (Dallman PR, et al. J Pediatr. 1979 Jan;94(1):26-31). Testing for EPO when the hemoglobin level was elevated showed a level of 8.1 mIU/ml, which was within the normal range for the patient’s age group (Krafte-Jacobs B, et al. J Pediatr. 1995 Apr;126(4):601-3). After tumor resection but before the conclusion of the myleosuppressive chemotherapy, hemoglobin levels fell below 10 for the majority of time. Discussion Although there has been a case reported of a pediatric patient with neuroblastoma having erythrocytosis, this is the first case where the patient was actually found to have normal EPO levels. Case reports looking at EPO and erythrocytosis in children with Wilms tumors have reported a couple cases of children who had normal EPO levels (Lal A, et al. J Pediatr Hematol Oncol. 1997 May-Jun;19(3):263-5). This report showed no recurrence of polycythemia when the tumors were removed in these patients. The authors concluded that tumor or surrounding renal tissue was at some point producing EPO despite their inability to detect it. Conclusion We speculate that neuroblastoma tumors and possibly other pediatric tumors may be releasing a novel erythropoietic cytokine. Hormone-like cytokines have been reported with other cancers, such as hypercalcemia produced by PTH related peptide in breast and lung cancers. More research is needed to determine what, if any, novel EPO-like hormones are being released by neuroblastoma cells resulting in erythrocytosis despite normal EPO levels. Disclosures: No relevant conflicts of interest to declare.

Sign in / Sign up

Export Citation Format

Share Document