A protein identification algorithm for tandem mass spectrometry by incorporating the abundance of mRNA into a binomial probability scoring model

2019 ◽  
Vol 197 ◽  
pp. 53-59 ◽  
Author(s):  
Wen-Tai Ma ◽  
Zhao-Yu Liu ◽  
Xiao-Zhou Chen ◽  
Zhen-Liang Lin ◽  
Zhong-Bing Zheng ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Tandem Mass Spectrometry ◽  
Protein Identification ◽  
Identification Algorithm ◽  
Tandem Mass ◽  
Binomial Probability ◽  
Scoring Model

scholarly journals SQID: An Intensity-Incorporated Protein Identification Algorithm for Tandem Mass Spectrometry

2011 ◽  
Vol 10 (4) ◽  
pp. 1593-1602 ◽  
Author(s):  
Wenzhou Li ◽  
Li Ji ◽  
Jonathan Goya ◽  
Guanhong Tan ◽  
Vicki H. Wysocki
Keyword(s):  
Mass Spectrometry ◽  
Tandem Mass Spectrometry ◽  
Protein Identification ◽  
Identification Algorithm ◽  
Tandem Mass

Data Mining in Protein Identification by Tandem Mass Spectrometry

2011 ◽  
pp. 472-478
Author(s):  
Haipeng Wang
Keyword(s):  
Mass Spectrometry ◽  
Data Mining ◽  
Tandem Mass Spectrometry ◽  
Large Scale ◽  
Protein Identification ◽  
Peptide Fragmentation ◽  
Tandem Mass ◽  
Fragmentation Pattern ◽  
Post Translational Modification ◽  
Challenges And Opportunities

Protein identification (sequencing) by tandem mass spectrometry is a fundamental technique for proteomics which studies structures and functions of proteins in large scale and acts as a complement to genomics. Analysis and interpretation of vast amounts of spectral data generated in proteomics experiments present unprecedented challenges and opportunities for data mining in areas such as data preprocessing, peptide-spectrum matching, results validation, peptide fragmentation pattern discovery and modeling, and post-translational modification (PTM) analysis. This article introduces the basic concepts and terms of protein identification and briefly reviews the state-of-the-art relevant data mining applications. It also outlines challenges and future potential hot spots in this field.

scholarly journals EBP, a Program for Protein Identification Using Multiple Tandem Mass Spectrometry Datasets

2006 ◽  
Vol 6 (3) ◽  
pp. 527-536 ◽  
Author(s):  
Thomas S. Price ◽  
Margaret B. Lucitt ◽  
Weichen Wu ◽  
David J. Austin ◽  
Angel Pizarro ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Tandem Mass Spectrometry ◽  
Protein Identification ◽  
Tandem Mass
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