Should Geometric Mean Calculation of Differential Renal Function be Used When Evaluating Children with Moderate to Severe Hydronephrosis?

2016 ◽  
Vol 195 (2) ◽  
pp. 247-248 ◽  
Author(s):  
Paul A. Merguerian
2001 ◽  
Vol 40 (04) ◽  
pp. 107-110 ◽  
Author(s):  
B. Roßmüller ◽  
S. Alalp ◽  
S. Fischer ◽  
S. Dresel ◽  
K. Hahn ◽  
...  

SummaryFor assessment of differential renal function (PF) by means of static renal scintigraphy with Tc-99m-dimer-captosuccinic acid (DMSA) the calculation of the geometric mean of counts from the anterior and posterior view is recommended. Aim of this retrospective study was to find out, if the anterior view is necessary to receive an accurate differential renal function by calculating the geometric mean compared to calculating PF using the counts of the posterior view only. Methods: 164 DMSA-scans of 151 children (86 f, 65 m) aged 16 d to 16 a (4.7 ± 3.9 a) were reviewed. The scans were performed using a dual head gamma camera (Picker Prism 2000 XP, low energy ultra high resolution collimator, matrix 256 x 256,300 kcts/view, Zoom: 1.6-2.0). Background corrected values from both kidneys anterior and posterior were obtained. Using region of interest technique PF was calculated using the counts of the dorsal view and compared with the calculated geometric mean [SQR(Ctsdors x Ctsventr]. Results: The differential function of the right kidney was significantly less when compared to the calculation of the geometric mean (p<0.01). The mean difference between the PFgeom and the PFdors was 1.5 ± 1.4%. A difference > 5% (5.0-9.5%) was obtained in only 6/164 scans (3.7%). Three of 6 patients presented with an underestimated PFdors due to dystopic kidneys on the left side in 2 patients and on the right side in one patient. The other 3 patients with a difference >5% did not show any renal abnormality. Conclusion: The calculation of the PF from the posterior view only will give an underestimated value of the right kidney compared to the calculation of the geometric mean. This effect is not relevant for the calculation of the differntial renal function in orthotopic kidneys, so that in these cases the anterior view is not necesssary. However, geometric mean calculation to obtain reliable values for differential renal function should be applied in cases with an obvious anatomical abnormality.


2007 ◽  
Vol 177 (4S) ◽  
pp. 593-594
Author(s):  
Shelby N. Morrisroe ◽  
Erin P. Gibbons ◽  
Benjamin R. Stockton ◽  
Kyongtae T. Bae ◽  
Cheng Hong ◽  
...  

2006 ◽  
Vol 175 (4S) ◽  
pp. 245-245
Author(s):  
Joao L. Pippi Salle ◽  
Anthony J. Cook ◽  
Frank Papanicolaou ◽  
Darius J. Bagli ◽  
Farhat Walid ◽  
...  

1987 ◽  
Vol 60 (717) ◽  
pp. 869-872 ◽  
Author(s):  
R. Wujanto ◽  
R. S. Lawson ◽  
M. C. Prescott ◽  
H. J. Testa

2008 ◽  
Vol 65 (4) ◽  
pp. 299-302
Author(s):  
Boris Ajdinovic ◽  
Ljiljana Jaukovic ◽  
Amira Peco-Antic ◽  
Sanja Dugonjic

Background/Aim. Ureteropelvic junction obstruction and vesicoureteral reflux are the most frequent entities identified on the basis of antenatal hydronephrosis. The aim of this study was to determine the incidence and pattern of abnormal renal scintigraphy findings in postnatal investigation of children with antenatal hydronephrosis. Methods. Twenty four infants (19 boys and five girls) presented with antenatal hydronephrosis and mild to moderate hydronephrosis on ultrasound in newborn period were referred for renal scintigraphy. Ten patients with vesicoureteral reflux documented on micturating cystoureterography underwent 99mTc-DMSA renal scintigraphy and 14 patients were subjected to 99mTc-DTPA scintigraphy. Results. Anteroposterior pelvic diameter on ultrasound ranged from 11 to 24 mm. Renal DMSA scans identified congenital scars in two boys with bilateral reflux of grade V and unilateral reflux of grade III. Relative kidney uptake (RKU) less than 40% was found in three, and poor kidney function (RKU less than 10%) in two patients. Significant obstruction was shown on DTPA diuretic renal scintigraphy in 6/14 patients. Some slowing in dranaige (T1/2 greater than 10 minutes) with no reduction in differential renal function was identified in three patients. Differential renal function less than 10% was obtained in one case. Conclusion. A high percent of abnormal renal scintigraphy findings was obtained. Renal scintigraphy was useful in determination of underlying cause of antenatally detected hydronephrosis.


2012 ◽  
Vol 35 (2) ◽  
pp. 59-61
Author(s):  
Gazi Zahirul Hasan ◽  
AKM Zahid Hossain ◽  
Md Ruhul Amin ◽  
Shafiqul Hoque ◽  
MTH Siddiqui

Objective: To compare between nonintubated versus intubated Anderson-Hynes (AH) pyeloplasty in children.Study Design: Prospective studyStudy place: Department of Paediatric Surgery, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh and some private clinics of Dhaka city. Study period: March 2001 to December 2008.Subjects: A total of 75 patients were included in this study. They were divided in two groups. Nonintubated Anderson-Hynes pyeloplasty was done in 45 patients and intubated Anderson-Hynes pyeloplasty was done in 30 patients.Results: The anastomotic leakage of urine, urinary tract infection, hospital stay and improvement of differential renal function were assessed post operatively in both nonintubated and intubated groups. This study showed that there was no anastomotic failure and no post operative urinary tract infection in either group. The percentage of improvement of differential renal function is almost same in both the groups. The post operative hospital stay was markedly reduced in nonintubated Anderson-Hynes pyeloplasty. In this study the post operative hospital stay in nonintubated group was average 6 days and it was average 16.5 days in intubated group.Conclusion: From this study it may be concluded that the effects of nonintubated AH pyeloplasty is as good as intubated one but an additional advantage of significantly less post operative hospital stay was observed in nonintubated group.DOI: http://dx.doi.org/10.3329/bjch.v35i2.10378  Bangladesh J Child Health 2011; Vol 35 (2): 59-61


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