scholarly journals Budget Impact Analysis of The Use of Extended Half-Life Recombinant Factor VIII (EFMOROCTOG ALFA) For The Treatment of Congenital Haemophilia A: The Italian National Health System Perspective

2016 ◽  
Vol 19 (7) ◽  
pp. A580
Author(s):  
V Lorenzoni ◽  
Triulzi ◽  
G Turchetti
Keyword(s):  
Factor Viii ◽  
Health System ◽  
Half Life ◽  
Impact Analysis ◽  
Budget Impact ◽  
National Health System ◽  
Haemophilia A ◽  
System Perspective ◽  
Italian National Health ◽  
Health System Perspective

scholarly journals Budget Impact Analysis of Surfactant Therapy for Bronchiolitis In Critically Ill Infants: The Colombian National Health System Perspective

2021 ◽  
Author(s):  
jefferson buendia ◽  
Diana Guerrero Patiño
Keyword(s):  
Mechanical Ventilation ◽  
Health System ◽  
Critically Ill ◽  
National Health ◽  
Impact Analysis ◽  
Budget Impact ◽  
National Health System ◽  
Surfactant Therapy ◽  
System Perspective ◽  
Health System Perspective

Abstract BACKGROUND: Exogen surfactant in mechanically ventilated infants decreased duration of stay in the intensive care unit and had favorable effects on oxygenation and carbon dioxide removal. This study aimed to evaluate the budget impact of surfactant therapy for bronchiolitis in critically ill infants in Colombia.METHODS: Budget impact analysis was performed to estimate the economic impact of surfactant therapy (ST) for the treatment of infants with a diagnosis of bronchiolitis, requiring mechanical ventilation. The analysis considered a 4-year time horizon and Colombian National Health System perspective. The model estimated drug costs associated with current scenario using humidified oxygen or adrenaline nebulization , and new scenario adding exogen surfactant. The size of the target population was calculated using epidemiological national data. Univariate one-way sensitivity analyses and scenario analyses were performed.RESULTS: In the base-case analysis the 4-year costs associated to ST and no-ST were estimated to be US$ 55.188.132 and US$ 55.972.082 respectively, indicating savings for Colombian National Health equal to US% 783.950 if ST is adopted for the routine management of patients with bronchiolitis requiring mechanical ventilation. Results were consistent at variation of most of the model’s parameters; only in case of increases of drug cost of surfactant and daily cost or length of stay in pediatric intensive unit , the savings are reducedCONCLUSION: ST was cost-saving in emergency settings for treating infants with severe bronchiolitis requiring mechanical ventilation. This shift in treatment approach proved to be economically favorable in the Colombian context.

scholarly journals Budget impact analysis of surfactant therapy for bronchiolitis in critically ill infants: the Colombian National Health System perspective

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Jefferson Antonio Buendía ◽  
Diana Guerrero Patiño
Keyword(s):  
Mechanical Ventilation ◽  
Health System ◽  
Critically Ill ◽  
National Health ◽  
Impact Analysis ◽  
Budget Impact ◽  
National Health System ◽  
Surfactant Therapy ◽  
System Perspective ◽  
Health System Perspective

Abstract Background Severe bronchiolitis requiring mechanical ventilation was associated with an absence of surfactant activity and phosphatidylglycerol, causing airway obstruction in acute bronchiolitis. Exogen surfactant in mechanically ventilated infants decreased duration of stay in the intensive care unit and had favorable effects on oxygenation and carbon dioxide removal. This study aimed to evaluate the budget impact of surfactant therapy for bronchiolitis in critically ill infants in Colombia. Methods Budget impact analysis was performed to estimate the economic impact of surfactant therapy (ST) for the treatment of infants with a diagnosis of bronchiolitis, requiring mechanical ventilation. The analysis considered a 4-year time horizon and Colombian National Health System perspective. The model estimated drug costs associated with current scenario using humidified oxygen or adrenaline nebulization, and new scenario adding exogen surfactant. The size of the target population was calculated using epidemiological national data. Univariate one-way sensitivity analyses and scenario analyses were performed. Results In the base-case analysis the 4-year costs associated to ST and no-ST were estimated to be US$ 55,188,132 and US$ 55,972,082 respectively, indicating savings for Colombian National Health equal to US$ 783,950 if ST is adopted for the routine management of patients with bronchiolitis requiring mechanical ventilation. In the one-way sensitivity analysis, only increases in the cost of the surfactant drug and cost or length of stay in the pediatric intensive unit reduce the potential savings of ST. Conclusion ST was cost-saving in emergency settings for treating infants with severe bronchiolitis requiring mechanical ventilation. This shift in treatment approach proved to be economically favorable in the Colombian context.

scholarly journals Budget Impact Analysis of Xydalba from the Perspective of Italian National Health System

2016 ◽  
Vol 19 (7) ◽  
pp. A564-A565
Author(s):  
A Marcellusi ◽  
C Bini ◽  
N Petrosillo ◽  
FS Mennini ◽  
P Sciattella
Keyword(s):  
Health System ◽  
National Health ◽  
Impact Analysis ◽  
Budget Impact ◽  
National Health System ◽  
Budget Impact Analysis ◽  
Italian National Health

scholarly journals Budget impact analysis of Fractional Exhaled Nitric Oxide Monitoring for the Management of Childhood Asthma: The Colombian National Health System perspective

2021 ◽  
Vol 32 (2) ◽  
Author(s):  
JA Buendía ◽  
R Acuña-Cordero ◽  
CE Rodriguez-Martinez
Keyword(s):  
Nitric Oxide ◽  
National Health ◽  
Impact Analysis ◽  
Budget Impact ◽  
National Health System ◽  
Persistent Asthma ◽  
Exhaled Nitric Oxide ◽  
Fractional Exhaled Nitric Oxide ◽  
System Perspective ◽  
The Cost

Background: Fractional exhaled nitric oxide is a simple, non-invasive measurement of airway inflammation with minimal discomfort with results available within a few minutes. For policymakers, the main concerns is the economic impact implicated in adapting this technology, especially in developing countries. This study to evaluate the budget impact of asthma management using fractional exhaled nitric oxide monitoring in patients between 4 and 18 years of age in Colombia. Methods: A budget impact analysis was performed to evaluate the potential financial impact deriving from Fractional exhaled nitric oxide. The analysis considered a 5-year time horizon and Colombian National Health System perspective. The incremental budget impact was calculated by subtracting the cost of the new treatment, in which FeNO is reimbursed, from the cost of the conventional treatment without FeNO (management based on clinical symptoms (with or without spirometry/peak flow) or asthma guidelines (or both), for asthma-related). Univariate one-way sensitivity analyses were performed. Results: In the base-case analysis the 5-year costs associated to FeNO and no-FeNO were estimated to be € 469.904.130 and € 480.485.149 respectively, indicating savings for Colombian National Health equal to € 10.581.019, if FeNO is adopted for the routine management of patients with persistent asthma. This result was robust in univariate sensitivity one-way analysis. Conclusion: Fractional exhaled nitric oxide was cost-saving in emergency settings for infants with persistent asthma. This evidence can be used by decision-makers in our country to improve clinical practice guidelines and should be replicated to validate their results in other middle-income countries.

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