Behavioral and biochemical characterization of a mutant mouse strain lacking d-amino acid oxidase activity and its implications for schizophrenia

2006 ◽  
Vol 32 (4) ◽  
pp. 324-334 ◽  
Author(s):  
S.L. Almond ◽  
R.L. Fradley ◽  
E.J. Armstrong ◽  
R.B. Heavens ◽  
A.R. Rutter ◽  
...  
Keyword(s):  
Amino Acid ◽  
Mouse Strain ◽  
Oxidase Activity ◽  
Mutant Mouse ◽  
Biochemical Characterization ◽  
Acid Oxidase ◽  
Amino Acid Oxidase ◽  
Mutant Mouse Strain

Behavioral characterization of a mutant mouse strain lacking d-amino acid oxidase activity

2011 ◽  
Vol 217 (1) ◽  
pp. 81-87 ◽  
Author(s):  
Min Zhang ◽  
Michael E. Ballard ◽  
Ana M. Basso ◽  
Natalie Bratcher ◽  
Kaitlin E. Browman ◽  
...  
Keyword(s):  
Amino Acid ◽  
Mouse Strain ◽  
Oxidase Activity ◽  
Mutant Mouse ◽  
Acid Oxidase ◽  
Amino Acid Oxidase ◽  
Mutant Mouse Strain ◽  
Behavioral Characterization

D-Aspartate oxidase activity and D-aspartate content in a mutant mouse strain lacking D-amino acid oxidase

1990 ◽  
Vol 46 (5) ◽  
pp. 468-470 ◽  
Author(s):  
H. Nagasaki ◽  
R. Yamada ◽  
R. Konno ◽  
Y. Yasumura ◽  
A. Iwashima
Keyword(s):  
Amino Acid ◽  
Mouse Strain ◽  
Oxidase Activity ◽  
Mutant Mouse ◽  
Acid Oxidase ◽  
Amino Acid Oxidase ◽  
Mutant Mouse Strain

Cloning and biochemical characterization of APIT, a new l-amino acid oxidase from Aplysia punctata

Toxicon ◽  
2005 ◽  
Vol 46 (5) ◽  
pp. 479-489 ◽  
Author(s):  
Daniel Butzke ◽  
Robert Hurwitz ◽  
Bernd Thiede ◽  
Sigrid Goedert ◽  
Thomas Rudel
Keyword(s):  
Amino Acid ◽  
Biochemical Characterization ◽  
Acid Oxidase ◽  
Amino Acid Oxidase

Impairment of Platelet Aggregation by Echis colorata Venom Mediated by L-Amino Acid Oxidase or H2O2

1982 ◽  
Vol 48 (03) ◽  
pp. 277-282 ◽  
Author(s):  
I Nathan ◽  
A Dvilansky ◽  
T Yirmiyahu ◽  
M Aharon ◽  
A Livne
Keyword(s):  
Hydrogen Peroxide ◽  
Amino Acid ◽  
Platelet Aggregation ◽  
Snake Venom ◽  
Oxidase Activity ◽  
Enzyme Preparation ◽  
Acid Oxidase ◽  
Crude Venom ◽  
Amino Acid Oxidase ◽  
Hemostatic Disorders

SummaryEchis colorata bites cause impairment of platelet aggregation and hemostatic disorders. The mechanism by which the snake venom inhibits platelet aggregation was studied. Upon fractionation, aggregation impairment activity and L-amino acid oxidase activity were similarly separated from the crude venom, unlike other venom enzymes. Preparations of L-amino acid oxidase from E.colorata and from Crotalus adamanteus replaced effectively the crude E.colorata venom in impairment of platelet aggregation. Furthermore, different treatments known to inhibit L-amino acid oxidase reduced in parallel the oxidase activity and the impairment potency of both the venom and the enzyme preparation. H2O2 mimicked characteristically the impairment effects of L-amino acid oxidase and the venom. Catalase completely abolished the impairment effects of the enzyme and the venom. It is concluded that hydrogen peroxide formed by the venom L-amino acid oxidase plays a role in affecting platelet aggregation and thus could contribute to the extended bleeding typical to persons bitten by E.colorata.

The Effect of Castration and Testosterone Propionate on d-Amino Acid Oxidase Activity in the Mouse

Science ◽  
1943 ◽  
Vol 98 (2534) ◽  
pp. 89-89
Author(s):  
L. C. Clark ◽  
C. D. Kochakian ◽  
R. Phyllis Fox
Keyword(s):  
Amino Acid ◽  
Oxidase Activity ◽  
Testosterone Propionate ◽  
Acid Oxidase ◽  
Amino Acid Oxidase

Comparative Characterization of Three D-Aspartate Oxidases and One D-Amino Acid Oxidase from Caenorhabditis elegans

2010 ◽  
Vol 7 (6) ◽  
pp. 1424-1434 ◽  
Author(s):  
Masumi Katane ◽  
Yasuaki Saitoh ◽  
Yousuke Seida ◽  
Masae Sekine ◽  
Takemitsu Furuchi ◽  
...  
Keyword(s):  
Amino Acid ◽  
Caenorhabditis Elegans ◽  
Acid Oxidase ◽  
Amino Acid Oxidase ◽  
Comparative Characterization
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