Quadruple concomitant non-bismuth therapy vs. classical triple therapy as first line therapy for Helicobacter pylori infection

2016 ◽  
Vol 147 (5) ◽  
pp. 199-201
Author(s):  
Ana Campillo ◽  
Miriam Ostiz ◽  
Edurne Amorena ◽  
Marcos Kutz ◽  
Matilde La Iglesia
Keyword(s):  
Helicobacter Pylori ◽  
Triple Therapy ◽  
Helicobacter Pylori Infection ◽  
First Line ◽  
First Line Therapy ◽  
Line Therapy

scholarly journals Additive Effect of Pronase on the Eradication Rate of First-Line Therapy for Helicobacter pylori Infection

Gut and Liver ◽  
2015 ◽  
Vol 9 (3) ◽  
Author(s):  
Chang Seok Bang ◽  
Yeon Soo Kim ◽  
Sang Hyun Park ◽  
Jin Bong Kim ◽  
Gwang Ho Baik ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Eradication Rate ◽  
Helicobacter Pylori Infection ◽  
Additive Effect ◽  
First Line ◽  
First Line Therapy ◽  
Line Therapy

Modified bismuth quadruple therapy with low‐dose metronidazole as first‐line therapy for Helicobacter pylori infection

Helicobacter ◽  
2020 ◽  
Author(s):  
Gyu Young Pih ◽  
Kee Don Choi ◽  
Eun Jeong Gong ◽  
Hee Kyong Na ◽  
Ji Yong Ahn ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Low Dose ◽  
Helicobacter Pylori Infection ◽  
First Line ◽  
Quadruple Therapy ◽  
First Line Therapy ◽  
Line Therapy

Levofloxacin-versus clarithromycin-based first line therapy for helicobacter pylori infection

2006 ◽  
Vol 38 ◽  
pp. S72
Author(s):  
A. Rispo ◽  
E. Di Girolamo ◽  
A. Cozzolino ◽  
L.M.A.T. Hamma ◽  
L. Pasquale
Keyword(s):  
Helicobacter Pylori ◽  
Helicobacter Pylori Infection ◽  
First Line ◽  
First Line Therapy ◽  
Line Therapy

scholarly journals Efficacy of two-week quadruple bismuth treatment versus levofloxacin concomitant Helicobacter Pylori infection regimen as empirical first-line therapy Syrian patients. A randomized controlled trial.

2020 ◽  
Author(s):  
Marouf Muhammad Alhalabi ◽  
Mohammed Waleed Alassi ◽  
Kamal Alaa Eddin ◽  
Khaled Cheha
Keyword(s):  
Randomized Controlled Trial ◽  
Helicobacter Pylori ◽  
Controlled Trial ◽  
Helicobacter Pylori Infection ◽  
First Line ◽  
Open Label ◽  
Randomized Controlled ◽  
First Line Therapy ◽  
Line Therapy

Abstract Introduction: Antibiotic-resistant reduces the efficacy of conventional triple therapy for Helicobacter Pylori infections worldwide, lead to varying treatment protocols according to locations.Aim: Primary outcome was eradication rates of bismuth quadruple (BQ) and levofloxacin concomitant (LC) as empirical first-line treatment by intention to treat (ITT) in a referral hospital in Syria.Design: an open‑label parallel blind randomized controlled trial.Materials and Methods: We randomly assigned seventy-eight naïve who tested positive for Helicobacter Pylori gastric infection, with a 1:1 ratio to receive either BQ (bismuth subsalicylate 524 mg four times daily, doxycycline 100 mg, tinidazole 500 mg, and esomeprazole 20 mg, each twice daily for two weeks), or LC (levofloxacin 500 mg daily, tinidazole 500 mg, amoxicillin 1000 mg, and esomeprazole 20 mg each twice daily for two weeks). We confirmed Helicobacter Pylori eradication by stool antigen test by eight weeks.Results: Thirty-nine patients were allocated in each group. In the BQ group, thirty-eight patients completed the follow-up, thirty patients were cured. While in the LC group, thirty-nine completed the follow-up, thirty-two patients were cured. The ITT eradication rates of the BQ and LC groups were 76.92%, and 82.05%, respectively. Odds ratio with 95% confidence interval according to ITT was 1.371 [0.454-4.146]. We didn’t report serious adverse effects.Conclusions:Both therapy regimens had acceptable rates of eradication. we suggest using both regimens as empirical first-line therapy in the treatment of Helicobacter Pylori infection in the Syrian population.Clinicaltrial.gov, NCT04348786

scholarly journals The Trend of Eradication Rate of Helicobacter pylori Infection and Clinical Factors That Affect the Eradication of First-line Therapy

2010 ◽  
Vol 55 (6) ◽  
pp. 368 ◽  
Author(s):  
Dong Keun Cho ◽  
Seon Young Park ◽  
Won Ju Kee ◽  
Jeong Hyeon Lee ◽  
Ho Seok Ki ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Eradication Rate ◽  
Helicobacter Pylori Infection ◽  
Clinical Factors ◽  
First Line ◽  
First Line Therapy ◽  
Line Therapy

scholarly journals Furazolidone-based first-line therapy for Helicobacter pylori infection in China: A meta-analysis

2016 ◽  
Vol 24 (33) ◽  
pp. 4484
Author(s):  
Xiang-Juan Qi ◽  
Bao-Xin Shi ◽  
Yong Jiang
Keyword(s):  
Helicobacter Pylori ◽  
Meta Analysis ◽  
Helicobacter Pylori Infection ◽  
First Line ◽  
First Line Therapy ◽  
Line Therapy
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