Upregulation of prostaglandin E2 and matrix metalloproteinase 9 production by human macrophage-like cells: Synergistic effect of capsular material and cell wall from Streptococcus suis

2006 ◽  
Vol 40 (1) ◽  
pp. 29-34 ◽  
Author(s):  
Marie-Claude Jobin ◽  
Marcelo Gottschalk ◽  
Daniel Grenier
Cytokine ◽  
2012 ◽  
Vol 58 (2) ◽  
pp. 199-206 ◽  
Author(s):  
Elizabeth A.B. Kelly ◽  
Lin Ying Liu ◽  
Stephane Esnault ◽  
Beatriz Helena Quinchia Johnson ◽  
Nizar N. Jarjour

2005 ◽  
Vol 167 (4) ◽  
pp. 1061-1069 ◽  
Author(s):  
Meng-Hsing Wu ◽  
Yutaka Shoji ◽  
Meng-Chi Wu ◽  
Pei-Chin Chuang ◽  
Chen-Chung Lin ◽  
...  

2005 ◽  
Vol 73 (10) ◽  
pp. 7064-7068 ◽  
Author(s):  
Elisabeth Elass ◽  
Laëtitia Aubry ◽  
Maryse Masson ◽  
Agnès Denys ◽  
Yann Guérardel ◽  
...  

ABSTRACT Lipomannans (LM) from various mycobacterial species were found to induce expression and secretion of the matrix metalloproteinase 9 (MMP-9) both in human macrophage-like differentiated THP-1 cells and in primary human macrophages. Inhibition studies using antireceptor-neutralizing antibodies are indicative of a Toll-like receptor 1 (TLR1)/TLR2- and CD14-dependent signaling mechanism. Moreover, LM was shown to down-regulate transcription of the metalloproteinase inhibitor TIMP-1, a major endogenous MMP-9 regulator.


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