New data in the enantioselective hydrogenation of ethyl pyruvate on Pt-cinchona chiral catalyst using continuous-flow fixed-bed reactor system: The origin of rate enhancement

2009 ◽  
Vol 305 (1-2) ◽  
pp. 155-160 ◽  
Author(s):  
György Szöllősi ◽  
Szabolcs Cserényi ◽  
Katalin Balázsik ◽  
Ferenc Fülöp ◽  
Mihály Bartók
Keyword(s):  
Continuous Flow ◽  
Ethyl Pyruvate ◽  
Fixed Bed ◽  
Enantioselective Hydrogenation ◽  
Reactor System ◽  
Fixed Bed Reactor ◽  
Chiral Catalyst ◽  
Rate Enhancement

Reversal of the ee in enantioselective hydrogenation of activated ketones in continuous-flow fixed-bed reactor system

2010 ◽  
Vol 12 (1) ◽  
pp. 14-19 ◽  
Author(s):  
Szabolcs Cserényi ◽  
György Szőllősi ◽  
Kornél Szőri ◽  
Ferenc Fülöp ◽  
Mihály Bartók
Keyword(s):  
Continuous Flow ◽  
Fixed Bed ◽  
Enantioselective Hydrogenation ◽  
Reactor System ◽  
Fixed Bed Reactor

Design of a continuous flow immobilized-cell reactor for biosynthetical production of L-aspartic acid

1985 ◽  
Vol 50 (10) ◽  
pp. 2122-2133 ◽  
Author(s):  
Jindřich Zahradník ◽  
Marie Fialová ◽  
Jan Škoda ◽  
Helena Škodová
Keyword(s):  
Aspartic Acid ◽  
Continuous Flow ◽  
Immobilized Cells ◽  
Scale Up ◽  
Fixed Bed ◽  
Packed Bed ◽  
Fixed Bed Reactor ◽  
Experimental Program ◽  
Design Parameters ◽  
Immobilized Cell

An experimental study was carried out aimed at establishing a data base for an optimum design of a continuous flow fixed-bed reactor for biotransformation of ammonium fumarate to L-aspartic acid catalyzed by immobilized cells of the strain Escherichia alcalescens dispar group. The experimental program included studies of the effect of reactor geometry, catalytic particle size, and packed bed arrangement on reactor hydrodynamics and on the rate of substrate conversion. An expression for the effective reaction rate was derived including the effect of mass transfer and conditions of the safe conversion-data scale-up were defined. Suggestions for the design of a pilot plant reactor (100 t/year) were formulated and decisive design parameters of such reactor were estimated for several variants of problem formulation.

Sign in / Sign up

Export Citation Format

Share Document