Anti-tumor activity of folate targeted biodegradable polymer–paclitaxel conjugate micelles on EMT-6 breast cancer model

2015 ◽  
Vol 53 ◽  
pp. 68-75 ◽  
Author(s):  
Di Wu ◽  
Yonghui Zheng ◽  
Xiuli Hu ◽  
Zhimin Fan ◽  
Xiabin Jing
Keyword(s):  
Breast Cancer ◽  
Biodegradable Polymer ◽  
Cancer Model ◽  
Breast Cancer Model ◽  
Anti Tumor Activity

Structure-based discovery of a small non-peptidic Neuropilins antagonist exerting in vitro and in vivo anti-tumor activity on breast cancer model

2014 ◽  
Vol 349 (2) ◽  
pp. 120-127 ◽  
Author(s):  
Lucia Borriello ◽  
Matthieu Montès ◽  
Yves Lepelletier ◽  
Bertrand Leforban ◽  
Wang-Qing Liu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Model ◽  
Breast Cancer Model ◽  
Anti Tumor Activity

scholarly journals Demonstration of anti-tumor activity of oncolytic measles virus strains in a malignant pleural effusion breast cancer model

2009 ◽  
Vol 122 (3) ◽  
pp. 745-754 ◽  
Author(s):  
Ianko D. Iankov ◽  
Pavlos Msaouel ◽  
Cory Allen ◽  
Mark J. Federspiel ◽  
Peggy A. Bulur ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Pleural Effusion ◽  
Measles Virus ◽  
Malignant Pleural Effusion ◽  
Cancer Model ◽  
Breast Cancer Model ◽  
Anti Tumor Activity ◽  
Virus Strains

scholarly journals Osteopontin binds ICOSL promoting tumor metastasis

2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Davide Raineri ◽  
Chiara Dianzani ◽  
Giuseppe Cappellano ◽  
Federica Maione ◽  
Gianluca Baldanzi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Tumor Metastasis ◽  
Immune Checkpoints ◽  
Cancer Model ◽  
Therapeutic Approaches ◽  
Breast Cancer Model ◽  
4T1 Breast Cancer ◽  
Anti Tumor Activity

Abstract ICOSL/ICOS are costimulatory molecules pertaining to immune checkpoints; their binding transduces signals having anti-tumor activity. Osteopontin (OPN) is here identified as a ligand for ICOSL. OPN binds a different domain from that used by ICOS, and the binding induces a conformational change in OPN, exposing domains that are relevant for its functions. Here we show that in vitro, ICOSL triggering by OPN induces cell migration, while inhibiting anchorage-independent cell growth. The mouse 4T1 breast cancer model confirms these data. In vivo, OPN-triggering of ICOSL increases angiogenesis and tumor metastatization. The findings shed new light on ICOSL function and indicate that another partner beside ICOS may be involved; they also provide a rationale for developing alternative therapeutic approaches targeting this molecular trio.

scholarly journals Interleukin-7 Enhances the in Vivo Anti-tumor Activity of Tumor-reactive CD8+T cells with Induction of IFN-gamma in a Murine Breast Cancer Model

2014 ◽  
Vol 15 (1) ◽  
pp. 265-271 ◽  
Author(s):  
Chun-Hui Yuan ◽  
Xue-Qin Yang ◽  
Cheng-Liang Zhu ◽  
Shao-Ping Liu ◽  
Bi-Cheng Wang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
T Cells ◽  
Cd8 T Cells ◽  
Cancer Model ◽  
Ifn Gamma ◽  
Interleukin 7 ◽  
Breast Cancer Model ◽  
Anti Tumor Activity

Lifelong isoflavone exposure and its implications in an experimental breast cancer model

2015 ◽  
Vol 122 (03) ◽  
Author(s):  
FJ Möller ◽  
K Wende ◽  
O Zierau ◽  
MC Bosland ◽  
MH Muders ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Model ◽  
Breast Cancer Model

Systemic Immunotherapy with Micellar Resiquimod–Polymer Conjugates Triggers a Robust Antitumor Response in a Breast Cancer Model

2021 ◽  
pp. 2100008
Author(s):  
Hamilton Kakwere ◽  
Hua Zhang ◽  
Elizabeth S. Ingham ◽  
Marina Nura‐Raie ◽  
Spencer K. Tumbale ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Model ◽  
Antitumor Response ◽  
Polymer Conjugates ◽  
Breast Cancer Model ◽  
Systemic Immunotherapy

scholarly journals Thermal analysis of laser irradiation-gold nanorod combinations at 808 nm, 940 nm, 975 nm and 1064 nm wavelengths in breast cancer model

2021 ◽  
Vol 38 (1) ◽  
pp. 1099-1110
Author(s):  
Leonardo Bianchi ◽  
Rachael Mooney ◽  
Yvonne R. Cornejo ◽  
Emiliano Schena ◽  
Jacob M. Berlin ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Thermal Analysis ◽  
Laser Irradiation ◽  
Gold Nanorod ◽  
Cancer Model ◽  
Breast Cancer Model
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