Mini Review: The Relationship between Energy Status and Adult Hippocampal Neurogenesis

2021 ◽  
pp. 136261
Author(s):  
Taylor Landry ◽  
Hu Huang
Hippocampus ◽  
2016 ◽  
Vol 26 (7) ◽  
pp. i-i
Author(s):  
Simona Gradari ◽  
Paloma Pérez-Domper ◽  
Ray G. Butler ◽  
Carmen Martínez-Cué ◽  
Gonzalo G. de Polavieja ◽  
...  

Hippocampus ◽  
2016 ◽  
Vol 26 (7) ◽  
pp. 857-874 ◽  
Author(s):  
Simona Gradari ◽  
Paloma Pérez-Domper ◽  
Ray G. Butler ◽  
Carmen Martínez-Cué ◽  
Gonzalo G. de Polavieja ◽  
...  

2015 ◽  
Vol 2015 ◽  
pp. 1-13 ◽  
Author(s):  
Suk-yu Yau ◽  
Ang Li ◽  
Kwok-Fai So

Adult hippocampal neurogenesis is a process involving the continuous generation of newborn neurons in the hippocampus of adult animals. Mounting evidence has suggested that hippocampal neurogenesis contributes to some forms of hippocampus-dependent learning and memory; however, the detailed mechanism concerning how this small number of newborn neurons could affect learning and memory remains unclear. In this review, we discuss the relationship between adult-born neurons and learning and memory, with a highlight on recently discovered potential roles of neurogenesis in pattern separation and forgetting.


2021 ◽  
Vol 12 ◽  
Author(s):  
Sarah Houben ◽  
Mégane Homa ◽  
Zehra Yilmaz ◽  
Karelle Leroy ◽  
Jean-Pierre Brion ◽  
...  

Adult hippocampal neurogenesis (AHN) has been widely confirmed in mammalian brains. A growing body of evidence points to the fact that AHN sustains hippocampal-dependent functions such as learning and memory. Impaired AHN has been reported in post-mortem human brain hippocampus of Alzheimer's disease (AD) and is considered to contribute to defects in learning and memory. Neurofibrillary tangles (NFTs) and amyloid plaques are the two key neuropathological hallmarks of AD. NFTs are composed of abnormal tau proteins accumulating in many brain areas during the progression of the disease, including in the hippocampus. The physiological role of tau and impact of tau pathology on AHN is still poorly understood. Modifications in AHN have also been reported in some tau transgenic and tau-deleted mouse models. We present here a brief review of advances in the relationship between development of tau pathology and AHN in AD and what insights have been gained from studies in tau mouse models.


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