Peritrabecular clefting in fibrous dysplasia of the jaws: an important histopathologic feature for differentiating fibrous dysplasia from central ossifying fibroma

Juvenile Psammomatoid Ossifying Fibromais a rare fibro-osseous tumor seen in children and adolescentand mostly arising from the cranio-facial bone.We report a case of 18-year-old boy who presented with diplopiaand progressive right fronto-orbital swelling. On plain radiograph and CT, it was diagnosed as fibrous dysplasiaand mucocele as differential diagnosis. The tumor was resected and histopathological examination showed psammomatoid features. Therefore, the diagnosis of Juvenile Psammomatoid Ossifying Fibroma must be based on both radiological and histopathological findings.

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HRPT2 and cyclin D1 molecular investigation in fibrous dysplasia, ossifying fibroma and osteosarcoma of the jaws

Oral Surgery Oral Medicine Oral Pathology and Oral Radiology ◽

10.1016/j.oooo.2012.08.293 ◽

2012 ◽

Vol 114 (4) ◽

pp. e105-e106

Keyword(s):

Cyclin D1 ◽

Fibrous Dysplasia ◽

Ossifying Fibroma ◽

Molecular Investigation

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Imaging in the Diagnosis of Cemento-Ossifying Fibroma: A Case Series

Journal of Clinical Imaging Science ◽

10.4103/2156-7514.100373 ◽

2012 ◽

Vol 2 ◽

pp. 52 ◽

Cited By ~ 5

Author(s):

R Mithra ◽

Pavitra Baskaran ◽

M Sathyakumar

Keyword(s):

Treatment Planning ◽

Fibrous Dysplasia ◽

Case Series ◽

Disease Process ◽

Ossifying Fibroma ◽

Imaging Findings ◽

The Third ◽

Osseous Lesion ◽

Essential Tool ◽

Slow Growing

Cemento-ossifying fibroma is a benign fibro-osseous lesion belonging to the same category as fibrous dysplasia and cementifying dysplasia. These are slow-growing lesions that are seen in the third and fourth decades of life. Both the ossifying fibroma and cemento-ossifying fibroma represent two extremes of the same disease process since histologically both contain bone and cementum. However, the term cemento-ossifying fibroma is justified on the basis of clinical and radiological correlation. Radiographs have become an essential tool in the diagnosis of lesions in the jaw, where the anatomy is complex. Nowadays, CT provides information for diagnosis as well as treatment planning. In this case series, we report three cases of cemento-ossifying fibroma that were histologically confirmed and discuss the imaging findings.

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Differential Diagnosis of Fibro-Osseous Jaw Lesions (Fibrous Dysplasia vs. Ossifying Fibroma)

Beiträge zur Pathologie ◽

10.1016/s0005-8165(73)80032-0 ◽

1973 ◽

Vol 148 (3) ◽

pp. 221-229 ◽

Cited By ~ 8

Author(s):

H. Peter Meister ◽

W. Lufft ◽

D. Schlegel

Keyword(s):

Differential Diagnosis ◽

Fibrous Dysplasia ◽

Ossifying Fibroma

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Ossifying fibroma vs fibrous dysplasia of the jaw: molecular and immunological characterization

Yearbook of Pathology and Laboratory Medicine ◽

10.1016/s1077-9108(08)70666-2 ◽

2008 ◽

Vol 2008 ◽

pp. 205-208

Author(s):

Raja Seethala

Keyword(s):

Fibrous Dysplasia ◽

Ossifying Fibroma ◽

Immunological Characterization

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Pedal Osteosarcoma in a Donkey

Veterinary Pathology ◽

10.1177/030098589803500510 ◽

1998 ◽

Vol 35 (5) ◽

pp. 407-409 ◽

Cited By ~ 12

Author(s):

A. M. Nelson ◽

D. C. Baker

Keyword(s):

Fibrous Dysplasia ◽

Mesenchymal Cells ◽

Careful Consideration ◽

Ossifying Fibroma ◽

Dorsal Aspect ◽

Histological Characteristics ◽

Cut Surface

An 18 1/2-year-old castrated male donkey with progressively worsening right forelimb lameness presented with a mass on the distal dorsal aspect of its P3 bone. Grossly, the firm, gritty mass was infiltrative, disrupted the contours of the overlying hoof wall, and had mottled and cavitated areas on cut surface. Histologically, the growth was composed of densely cellular sheets of mildly pleomorphic mesenchymal cells forming irregularly shaped islands of poorly mineralized osteoid. The neoplastic mass had patchy areas of necrosis. The diagnostic possibilities considered for this donkey's mass include osteosarcoma, osteoma, ossifying fibroma, and fibrous dysplasia. Careful consideration of the gross and histological characteristics of this donkey's mass support a diagnosis of osteosarcoma.

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