Can adenosine A2A receptor antagonists be used to treat cognitive impairment, depression or excessive sleepiness in Parkinson's disease?

Parkinsonism & Related Disorders ◽

10.1016/j.parkreldis.2020.09.022 ◽

2020 ◽

Vol 80 ◽

pp. S28-S36

Author(s):

Peter Jenner ◽

Akihisa Mori ◽

Tomoyuki Kanda

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Cognitive Impairment ◽

Adenosine A2a Receptor ◽

Receptor Antagonists ◽

Excessive Sleepiness ◽

Adenosine A2a Receptor Antagonists ◽

A2a Receptor ◽

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Adenosine A2A Receptor Antagonists in Parkinson’s Disease: Progress in Clinical Trials from the Newly Approved Istradefylline to Drugs in Early Development and Those Already Discontinued

CNS Drugs ◽

10.1007/s40263-014-0161-7 ◽

2014 ◽

Vol 28 (5) ◽

pp. 455-474 ◽

Author(s):

Annalisa Pinna

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Clinical Trials ◽

Early Development ◽

Adenosine A2a Receptor ◽

Receptor Antagonists ◽

Disease Progress ◽

Adenosine A2a Receptor Antagonists ◽

A2a Receptor ◽

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Adenosine A2A Receptor Antagonists for Parkinson’s Disease Treatment: 18 Years Adventure

Proceedings for Annual Meeting of The Japanese Pharmacological Society ◽

10.1254/jpssuppl.94.0_1-s03-2 ◽

2021 ◽

Vol 94 (0) ◽

pp. 1-S03-2

Author(s):

Jiang-Fan Chen

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Adenosine A2a Receptor ◽

Receptor Antagonists ◽

Disease Treatment ◽

Adenosine A2a Receptor Antagonists ◽

A2a Receptor ◽

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An Overview of Adenosine A2A Receptor Antagonists in Parkinson's Disease

International Review of Neurobiology - Adenosine Receptors in Neurology and Psychiatry ◽

10.1016/b978-0-12-801022-8.00003-9 ◽

2014 ◽

pp. 71-86 ◽

Author(s):

Peter Jenner

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Adenosine A2a Receptor ◽

Receptor Antagonists ◽

Adenosine A2a Receptor Antagonists ◽

A2a Receptor ◽

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Adenosine A2A Receptor Antagonists and Parkinson’s Disease

ACS Chemical Neuroscience ◽

10.1021/cn2000537 ◽

2011 ◽

Vol 2 (10) ◽

pp. 555-567 ◽

Author(s):

Brian C. Shook ◽

Paul F. Jackson

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Adenosine A2a Receptor ◽

Receptor Antagonists ◽

Adenosine A2a Receptor Antagonists ◽

A2a Receptor ◽

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Adenosine A2A receptor antagonists improve deficits in initiation of movement and sensory motor integration in the unilateral 6-hydroxydopamine rat model of Parkinson's disease

Synapse ◽

10.1002/syn.20410 ◽

2007 ◽

Vol 61 (8) ◽

pp. 606-614 ◽

Author(s):

Annalisa Pinna ◽

Silvia Pontis ◽

Franco Borsini ◽

Micaela Morelli

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Rat Model ◽

Adenosine A2a Receptor ◽

Receptor Antagonists ◽

Adenosine A2a Receptor Antagonists ◽

A2a Receptor ◽

Sensory Motor ◽

6 Hydroxydopamine ◽

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Protective Agents in Parkinson's Disease: Caffeine and Adenosine A2A Receptor Antagonists

Handbook of Neurotoxicity ◽

10.1007/978-1-4614-5836-4_103 ◽

2014 ◽

pp. 2281-2298

Author(s):

Nicola Simola ◽

Annalisa Pinna ◽

Lucia Frau ◽

Micaela Morelli

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Adenosine A2a Receptor ◽

Receptor Antagonists ◽

Protective Agents ◽

Adenosine A2a Receptor Antagonists ◽

A2a Receptor ◽

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Can adenosine A2A receptor antagonists modify motor behavior and dyskinesia in experimental models of Parkinson's disease?

Parkinsonism & Related Disorders ◽

10.1016/j.parkreldis.2020.09.026 ◽

2020 ◽

Vol 80 ◽

pp. S21-S27

Author(s):

Tomoyuki Kanda ◽

Peter Jenner

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Motor Behavior ◽

Experimental Models ◽

Adenosine A2a Receptor ◽

Receptor Antagonists ◽

Adenosine A2a Receptor Antagonists ◽

A2a Receptor ◽

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New adenosine A2A receptor antagonists: Actions on Parkinson's disease models

European Journal of Pharmacology ◽

10.1016/j.ejphar.2005.01.057 ◽

2005 ◽

Vol 512 (2-3) ◽

pp. 157-164 ◽

Author(s):

Annalisa Pinna ◽

Rosaria Volpini ◽

Gloria Cristalli ◽

Micaela Morelli

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Adenosine A2a Receptor ◽

Disease Models ◽

Receptor Antagonists ◽

Adenosine A2a Receptor Antagonists ◽

A2a Receptor ◽

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Adenosine A2A receptor antagonists as new agents for the treatment of Parkinson's disease

Trends in Pharmacological Sciences ◽

10.1016/s0165-6147(97)01096-1 ◽

1997 ◽

Vol 18 (9) ◽

pp. 338-344 ◽

Author(s):

P.J. Richardson ◽

H. Kase ◽

P.G. Jenner

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Adenosine A2a Receptor ◽

Receptor Antagonists ◽

Adenosine A2a Receptor Antagonists ◽

A2a Receptor ◽

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Novel neuroprotection by caffeine and adenosine A2A receptor antagonists in animal models of Parkinson's disease

Journal of the Neurological Sciences ◽

10.1016/j.jns.2006.05.003 ◽

2006 ◽

Vol 248 (1-2) ◽

pp. 9-15 ◽

Author(s):

Anti Kalda ◽

Liqun Yu ◽

Emin Oztas ◽

Jiang-Fan Chen

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Animal Models ◽

Adenosine A2a Receptor ◽

Receptor Antagonists ◽

Adenosine A2a Receptor Antagonists ◽

A2a Receptor ◽

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