scholarly journals Screening of congenital hypothyroidism in preterm, low birth weight and very low birth weight neonates: A systematic review

2018 ◽  
Vol 59 (1) ◽  
pp. 3-14 ◽  
Author(s):  
Mahin Hashemipour ◽  
Silva Hovsepian ◽  
Arman Ansari ◽  
Mojtaba Keikha ◽  
Pooyan Khalighinejad ◽  
...  
2016 ◽  
Vol 7 (4) ◽  
pp. 408-415 ◽  
Author(s):  
M. E. Tchamo ◽  
A. Prista ◽  
C. G. Leandro

Low birth weight (LBW<2500), very low birth weight (VLBW<1500), extremely low birth weight (ELBW<1500) infants are at high risk for growth failure that result in delayed development. Africa is a continent that presents high rates of children born with LBW, VLBW and ELBW particularly sub-Saharan Africa. To review the existing literature that explores the repercussions of LBW, VLBW and ELBW on growth, neurodevelopmental outcome and mortality in African children aged 0–5 years old. A systematic review of peer-reviewed articles using Academic Search Complete in the following databases: PubMed, Scopus and Scholar Google. Quantitatives studies that investigated the association between LBW, VLBW, ELBW with growth, neurodevelopmental outcome and mortality, published between 2008 and 2015 were included. African studies with humans were eligible for inclusion. From the total of 2205 articles, 12 articles were identified as relevant and were subsequently reviewed in full version. Significant associations were found between LBW, VLBW and ELBW with growth, neurodevelopmental outcome and mortality. Surviving VLBW and ELBW showed increased risk of death, growth retardation and delayed neurodevelopment. Post-neonatal interventions need to be carried out in order to minimize the short-term effects of VLBW and ELBW.


2020 ◽  
Vol 109 (10) ◽  
pp. 1974-1988 ◽  
Author(s):  
Sylvia Pal ◽  
Malte Steinhof ◽  
Manon Grevinga ◽  
Dieter Wolke ◽  
Gijsbert (Erik) Verrips

2020 ◽  
Vol 4 (Supplement_1) ◽  
Author(s):  
Seok-Jin Kang ◽  
Ga-Hyun Lee

Abstract The incidence of CH with a delayed TSH elevation was higher in ELBW and VLBW infants compared with infants weighing ≥1500 grams. Second screening should be considered in preterm neonates, low birth weight (LBW) and very low-birth weight (VLBW) neonates, ill and preterm newborns admitted to NICU, specimen collection within the first 24 hours of life, and multiple births (particularly same-sex twins). Purpose of this study was to determine incidence of delayed TSH elevation with or without congenital hypothyroidism in SGA infants and to Investigate necessity for second screening. Retrospective analysis was performed. 66 SGA newborns with 34-40 weeks’ gestation born at Keimyung University Dongsan Medical Center from 2015 to 2018 were enrolled. Primary screening was performed 48 hours - 7 days after birth. Second screening including venous TSH and venous free T4 at postnatal 8-40 days. Exclusion criteria were infants with congenital hypothyroidism at primary screening (NBS), descendants of mothers with immune thyroid disease, congenital malformations, renal, hepatic, and metabolic diseases, history of steroid or dopamine usage. Initial NBS were collected onto pre-printed filter at the age of 2-7 days by heel prick. (normal TSH &lt; 10 mIU/L). Second sample was obtained at the age of 8-49 days by venous sampling (normal TSH &lt; 5 mIU/L). TSH and free T4 were measured on venous samples with Cobas 8000 e801 (electrochemiluminescence, Roche, Diagnostics, Basel, Switzerland) using standard methods. Incidence of delayed TSH elevation was 27% (18/66). Of them number of transient hyperthyrotropinemia was 13. Mean TSH at initial elevation was 7.56 mIU/L and median age at initial TSH elevation was 18.6 days. Median age at resolution of TSH elevation was 41.5 days. Number of hypothyroidism undergoing l-thyroxine medication was 5. Mean TSH at initial elevation was 22.1 mIU/L. Median age at initial TSH elevation was 14 days. Mean peak TSH was 23.4 mIU/L. The presence of delayed TSH elevation was not related to very low birth weight. SGA infants might be at a risk of delayed TSH elevation. Considering 2nd screening test within 1 month. Further study with more SGA infants are needed. Limitation of this study was relative small number of patients and iodine status was not considered


2015 ◽  
Vol 30 (12) ◽  
pp. 1828 ◽  
Author(s):  
Hye Won Park ◽  
Gina Lim ◽  
Sung-Hoon Chung ◽  
Sochung Chung ◽  
Kyo Sun Kim ◽  
...  

2017 ◽  
Vol 118 ◽  
pp. 80-89 ◽  
Author(s):  
Fereshteh Farajdokht ◽  
Saeed Sadigh-Eteghad ◽  
Reza Dehghani ◽  
Gisou Mohaddes ◽  
Leili Abedi ◽  
...  

2009 ◽  
Vol 8 (2) ◽  
Author(s):  
Julianna Letícia Gimenes Cotrick Gomes ◽  
Edilaine Giovanini Rossetto ◽  
Sarah Nancy Deggau Hegeto de Souza ◽  
Carmen Gracinda Silvan Scochi

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