scholarly journals Cytotoxic, antimicrobial, antioxidant, antilipoxygenase activities and phenolic composition of Ozoroa and Searsia species (Anacardiaceae) used in South African traditional medicine for treating diarrhoea

2014 ◽  
Vol 95 ◽  
pp. 9-18 ◽  
Author(s):  
Aroke S. Ahmed ◽  
Lyndy J. McGaw ◽  
Nivan Moodley ◽  
Vinasan Naidoo ◽  
Jacobus N. Eloff
2019 ◽  
Vol 31 (11) ◽  
pp. 2623-2627
Author(s):  
M.A. Makhafola ◽  
L. Middleton ◽  
M.T. Olivier ◽  
O.O. Olaokun

Five plants were investigated for their antibacterial and cytotoxicity activities, namely: Lantana rugosa, Lippia javanica, Lippia wilmsii, Hilliardiella elaeagnoides and Withania somnifera. Four organisms and liver cells were used to evaluate the efficacy and the safety of the extracts from these plants. All the extracts showed antibacterial activity with the MIC ranging from 0.04 ± 0.04 mg/mL to 11.46 ± 9.66 mg/mL. The acetonic extract of L. javanica exhibited the highest antibacterial activity with MIC value of 0.04 ± 0.04 mg/mL against P. aeruginosa and 0.28 ± 0.35 mg/mL against S. aureus. Aqueous and acetonic extracts of L. wilmsii (LC50 > 1000 μg/mL) and the hexane extract of L. javanica (LC50 > 1000 μg/mL) were the least cytotoxic. While acetonic extract of L. javanica (0.01 ± 0.64 μg/mL) and hexane extract of L. wilmsii (0.03 ± 0.31 μg/mL) were the most cytotoxic.


ZooKeys ◽  
2013 ◽  
Vol 365 ◽  
pp. 215-233 ◽  
Author(s):  
Ledile Mankga ◽  
Yessoufou Kowiyou ◽  
Annah Moteetee ◽  
Barnabas Daru ◽  
Michelle van der Bank

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