Isolation and characterization of 5-hydroxymethylfurfural, antiglycation, antihyperglycaemic, antioxidant, and cytotoxic effects of Garcinia kola Heckel roots extract and fractions

2021 ◽  
Vol 140 ◽  
pp. 62-67
Author(s):  
Emmanuel E. Essien ◽  
Paul S. Thomas ◽  
Ime R. Ekanem ◽  
Mohammad I. Choudhary
Author(s):  
Yi Chen ◽  
Song-Wei Li ◽  
Fang-Zhou Yin ◽  
Min Yang ◽  
Xia-Juan Huan ◽  
...  

Abstract A phytochemical investigation of the EtOH extract of the flowers of Lagerstroemia indica L. led to the isolation and characterization of a new pyrrole alkaloid, named lagerindicine (1), along with four known compounds (2–5). Their structures were elucidated by the detailed spectroscopic analysis and comparison with literature data, whereas the structure, in particularly, the absolute configuration (AC) of 1, was firmly determined by total synthesis. All the isolates were evaluated for their cytotoxic effects against human colon cancer cell (HCT-116), and compound 3 exhibited weak cytotoxicity with IC50 value of 28.4 μM. Graphic Abstract


2016 ◽  
Vol 9 (5) ◽  
pp. 1-9
Author(s):  
A. Zakariya ◽  
U. Danmalam ◽  
A. Nuhu ◽  
A. Sallau ◽  
S. Shehu ◽  
...  

2021 ◽  
Vol 13 (4) ◽  
pp. 117-124
Author(s):  
Any Olivier Komenan ◽  
Kouamé Kévin Koffi ◽  
Moussa Koné ◽  
Kouakou Laurent Kouakou ◽  
Kouakou Guy-Casimir Douffi ◽  
...  

2000 ◽  
Vol 31 (2) ◽  
pp. 149-149 ◽  
Author(s):  
T Tozaki ◽  
H Kakoi ◽  
S Mashima ◽  
K Hirota ◽  
T Hasegawa ◽  
...  

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