Effects of biochar and thermally treated biochar on Eisenia fetida survival, growth, lysosomal membrane stability and oxidative stress

2021 ◽  
Vol 770 ◽  
pp. 144778
Author(s):  
Zhiming Shi ◽  
Jinhong Yan ◽  
Xingna Ren ◽  
Mei Wen ◽  
Yonghua Zhao ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Eisenia Fetida ◽  
Membrane Stability ◽  
Lysosomal Membrane ◽  
Lysosomal Membrane Stability ◽  
And Oxidative Stress ◽  
Thermally Treated

Suitability of lysosomal membrane stability in Eisenia fetida as biomarker of soil copper contamination

2011 ◽  
Vol 74 (4) ◽  
pp. 984-988 ◽  
Author(s):  
Annamaria Rocco ◽  
Janeck J. Scott-Fordsmand ◽  
Giulia Maisto ◽  
Sonia Manzo ◽  
Antonio Salluzzo ◽  
...  
Keyword(s):  
Eisenia Fetida ◽  
Membrane Stability ◽  
Lysosomal Membrane ◽  
Copper Contamination ◽  
Lysosomal Membrane Stability

Lysosomal membrane stability and metallothionein content in Mytilus galloprovincialis (L.), as biomarkers

2004 ◽  
Vol 48 (5-6) ◽  
pp. 572-586 ◽  
Author(s):  
G.P Domouhtsidou ◽  
S Dailianis ◽  
M Kaloyianni ◽  
V.K Dimitriadis
Keyword(s):  
Mytilus Galloprovincialis ◽  
Membrane Stability ◽  
Lysosomal Membrane ◽  
Lysosomal Membrane Stability

Elevated serum β-glucuronidase reflects hepatic lysosomal fragility following toxic liver injury in rats

2008 ◽  
Vol 86 (3) ◽  
pp. 235-243 ◽  
Author(s):  
Joseph George
Keyword(s):  
Liver Injury ◽  
Hepatic Fibrosis ◽  
Liver Homogenate ◽  
Lipid Peroxides ◽  
Membrane Stability ◽  
Lysosomal Membrane ◽  
Subcellular Fractions ◽  
Albino Rats ◽  
Nuclear Fraction ◽  
Lysosomal Membrane Stability

The level of serum β-glucuronidase increases in various pathological conditions, including liver disorders. The aim of this investigation was to study the changes in liver lysosomal membrane stability during experimentally induced hepatic fibrosis that may result in the elevation of serum β-glucuronidase. Liver injury was induced by intraperitoneal injections of N-nitrosodimethylamine (NDMA) in adult male albino rats over 3 weeks. The progression of fibrosis was evaluated histopathologically as well as by monitoring liver collagen content. Lipid peroxides and β-glucuronidase levels were measured in the liver homogenate and subcellular fractions on days 0, 7, 14, and 21 after the start of NDMA administration. Serum β-glucuronidase levels were also determined. A significant increase was observed in β-glucuronidase levels in the serum, liver homogenate, and subcellular fractions, but not in the nuclear fraction on days 7, 14, and 21 after the start of NDMA administration. Lipid peroxides also increased in the liver homogenate and the lysosomal fraction. The measurement of lysosomal membrane stability revealed a maximum lysosomal fragility on day 21 during NDMA-induced fibrosis. In vitro studies showed that NDMA has no significant effect on liver lysosomal membrane permeability. The results of this investigation demonstrated that lysosomal fragility increases during NDMA-induced hepatic fibrosis, which could be attributed to increased lipid peroxidation of lysosomal membrane. In this study, we also elucidated the mechanism of increased β-glucuronidase and other lysosomal glycohydrolases in the serum during hepatic fibrosis.

Sign in / Sign up

Export Citation Format

Share Document