Natural history of spinal deformity in a patient with Ehlers-Danlos syndrome: case report with 20-year follow-up

Abstract Background The natural course of a vortex vein varix, though not well understood, has been known to remain stable. However, here we report a novel case of a vortex vein varix that resolved after an extended period of monitoring. Case presentation An asymptomatic 96-year-old Caucasian man was found to have a vortex vein varix. At his previous examination 13 months prior, his fundus was normal. At 13 months of observation, his vortex vein varix become clinically undetectable. Further follow-up confirmed continued absence of the varix. Conclusion This case demonstrates the development then clinical resolution of a vortex vein varix with no clear identifiable factors for its evolution. This case is novel and offers new insight into the natural history of some vortex vein varices, implicating venous congestion as an instigator and venous collateralization as its alleviator, suggesting that vortex vein varices are likely more common than previously reported since some may be temporary and under-identified.

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Comment on: The multisystemic nature and natural history of joint hypermobility syndrome and Ehlers–Danlos syndrome in children: reply

Rheumatology ◽

10.1093/rheumatology/key252 ◽

2018 ◽

Vol 57 (12) ◽

pp. 2250-2251

Author(s):

Rodney Grahame

Keyword(s):

Natural History ◽

Joint Hypermobility ◽

Hypermobility Syndrome ◽

Joint Hypermobility Syndrome ◽

Ehlers Danlos Syndrome ◽

History Of ◽

Danlos Syndrome

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Spontaneous perforation of small intestine followed by rupture of the cystic artery: the natural history of Vascular Ehlers-Danlos Syndrome

Autopsy and Case Reports ◽

10.4322/acr.2018.054 ◽

2019 ◽

Vol 9 (1) ◽

Author(s):

Christopher Antônio Febres-Aldana ◽

Amilcar Antonio Castellano-Sanchez ◽

John Alexis

Keyword(s):

Small Intestine ◽

Natural History ◽

Cystic Artery ◽

Spontaneous Perforation ◽

Ehlers Danlos Syndrome ◽

History Of ◽

Danlos Syndrome

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The multisystemic nature and natural history of joint hypermobility syndrome and Ehlers–Danlos syndrome in children

Rheumatology ◽

10.1093/rheumatology/kex241 ◽

2017 ◽

Vol 56 (12) ◽

pp. 2048-2049 ◽

Cited By ~ 2

Author(s):

Rodney Grahame

Keyword(s):

Natural History ◽

Joint Hypermobility ◽

Hypermobility Syndrome ◽

Joint Hypermobility Syndrome ◽

Ehlers Danlos Syndrome ◽

History Of ◽

Danlos Syndrome

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Large choroidal excavation in myopic macular degeneration: A case report

European Journal of Ophthalmology ◽

10.1177/1120672120942748 ◽

2020 ◽

pp. 112067212094274 ◽

Cited By ~ 1

Author(s):

Federico Borghesan ◽

Alessandro Arrigo ◽

Francesco Bandello ◽

Maurizio Battaglia Parodi

Keyword(s):

Optical Coherence Tomography ◽

Case Report ◽

Natural History ◽

Macular Degeneration ◽

Fluorescein Angiography ◽

Clinical Features ◽

Multimodal Imaging ◽

Focal Choroidal Excavation ◽

History Of

Purpose: To report the morphological and clinical features of a case of myopic macular degeneration with large choroidal excavation. Methods: A myopic patient underwent multimodal imaging, including optical coherence tomography and fluorescein angiography, over a 8-year follow-up. Results: A choroidal excavation was found in left eye, superior to the fovea. The excavation started as a focal choroidal excavation (FCE) and got deeper and larger during the 8-years-long follow-up, thus resulting in a large choroidal excavation (LCE). Conclusions: LCE may be the evolution of FCE in highly myopic eyes, further studies are needed to describe the natural history of choroidal excavations in degenerative myopia.

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