Small molecule antagonist of C-C chemokine receptor 1 (CCR1) reduces disc inflammation in the rabbit model

2020 ◽  
Vol 20 (12) ◽  
pp. 2025-2036
Author(s):  
Po-Hsin Chou ◽  
Ana Chee ◽  
Peng Shi ◽  
Cheng-Li Lin ◽  
Yibo Zhao ◽  
...  
Keyword(s):  
Small Molecule ◽  
Chemokine Receptor ◽  
Rabbit Model ◽  
Small Molecule Antagonist ◽  
Chemokine Receptor 1

scholarly journals Site-directed Mutagenesis of CC Chemokine Receptor 1 Reveals the Mechanism of Action of UCB 35625, a Small Molecule Chemokine Receptor Antagonist

2004 ◽  
Vol 280 (6) ◽  
pp. 4808-4816 ◽  
Author(s):  
Filipa Lopes de Mendonça ◽  
Paula C. A. da Fonseca ◽  
Rhian M. Phillips ◽  
José W. Saldanha ◽  
Timothy J. Williams ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Small Molecule ◽  
Mechanism Of Action ◽  
Chemokine Receptor ◽  
Site Directed Mutagenesis ◽  
Directed Mutagenesis ◽  
Cc Chemokine ◽  
Chemokine Receptor Antagonist ◽  
Chemokine Receptor 1

Pharmacological Characterization of CXC Chemokine Receptor 3 Ligands and a Small Molecule Antagonist

2005 ◽  
Vol 313 (3) ◽  
pp. 1263-1271 ◽  
Author(s):  
Christopher E. Heise ◽  
Anil Pahuja ◽  
Sarah C. Hudson ◽  
Monica S. Mistry ◽  
Amy L. Putnam ◽  
...  
Keyword(s):  
Small Molecule ◽  
Chemokine Receptor ◽  
Pharmacological Characterization ◽  
Small Molecule Antagonist ◽  
Cxc Chemokine

scholarly journals PositiveVersusNegative Modulation of Different Endogenous Chemokines for CC-chemokine Receptor 1 by Small Molecule Agonists through AllostericVersusOrthosteric Binding

2008 ◽  
Vol 283 (34) ◽  
pp. 23121-23128 ◽  
Author(s):  
Pia C. Jensen ◽  
Stefanie Thiele ◽  
Trond Ulven ◽  
Thue W. Schwartz ◽  
Mette M. Rosenkilde
Keyword(s):  
Small Molecule ◽  
Chemokine Receptor ◽  
Cc Chemokine ◽  
Chemokine Receptor 1

Species selectivity of a small molecule antagonist for the CCR1 chemokine receptor

2000 ◽  
Vol 389 (1) ◽  
pp. 41-49 ◽  
Author(s):  
Meina Liang ◽  
Mary Rosser ◽  
Howard P Ng ◽  
Karen May ◽  
John G Bauman ◽  
...  
Keyword(s):  
Small Molecule ◽  
Chemokine Receptor ◽  
Small Molecule Antagonist ◽  
Species Selectivity

Pharmacology of AMD3465: A small molecule antagonist of the chemokine receptor CXCR4

2009 ◽  
Vol 78 (8) ◽  
pp. 993-1000 ◽  
Author(s):  
Veronique Bodart ◽  
Virginia Anastassov ◽  
Marilyn C. Darkes ◽  
Stefan R. Idzan ◽  
Jean Labrecque ◽  
...  
Keyword(s):  
Small Molecule ◽  
Chemokine Receptor ◽  
Small Molecule Antagonist ◽  
Chemokine Receptor Cxcr4
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