Evaluation of magnetic resonance imaging criteria for cavernous sinus invasion in patients with pituitary adenomas: logistic regression analysis and correlation with surgical findings

Abstract Magnetic resonance imaging (MRI), computed tomographic (CT) scanning, and angiography or digital subtraction angiography (DSA) were used preoperatively to evaluate 16 surgically proven cases of sellar tumor with extrasellar extension. There were 15 pituitary tumors and 1 schwannoma. The capabilities of MRI in evaluating these tumors were compared with CT scanning and angiography. Bone destruction and tumor calcification were better detected by CT scanning than by MRI. MRI was as effective as CT scanning in detecting a cyst or variation in tumor consistency. Neither MRI nor CT scanning was capable of distinguishing specific tumor types. In every case, MRI was superior to CT scanning for delineating spatial relationships of the tumor to the 3rd ventricle, the optic apparatus, adjacent brain, and parasellar vasculature. Vessel encasement by tumor was clearly seen on MRI when there was no direct indication of this on other studies. Cavernous sinus invasion was not demonstrated by CT scanning, but was indicated by MRI in 5 cases and was surgically confirmed in 3. MRI can provide more precise spatial information on extrasellar tumor extension. Vascular encasement and cavernous sinus invasion may be determined preoperatively. Treatment expectations and operative approaches can be guided by this information. When MRI is available, it is the test of choice for the preoperative evaluation of patients with suspected large pituitary gland (sellar region) tumors. Contrast-enhanced CT scanning and angiography can be used as supplementary studies to add information inherently unique to these techniques. (Neurosurgery 21:540-546, 1987)

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Magnetic Resonance Imaging and Biological Markers in Pituitary Adenomas with Invasion of the Cavernous Sinus Space

The Chinese-German Journal of Clinical Oncology ◽

10.1007/s10330-004-0247-7 ◽

2005 ◽

Vol 4 (1) ◽

pp. 30-35

Author(s):

Lixiong PAN ◽

Yunsheng LIU ◽

Jihong ZHAO ◽

Zhongping CHEN

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Cavernous Sinus ◽

Biological Markers ◽

Pituitary Adenomas ◽

Resonance Imaging ◽

And Biological Markers

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Relationship between magnetic resonance imaging lesions and knee symptoms in early knee osteoarthritis: A cross-sectional Japanese population study

10.21203/rs.3.rs-44187/v1 ◽

2020 ◽

Author(s):

Seiya Ota ◽

Eiji Sasaki ◽

Shizuka Sasaki ◽

Daisuke Chiba ◽

Yuka Kimura ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Logistic Regression ◽

Regression Analysis ◽

Magnetic Resonance ◽

Cartilage Damage ◽

Resonance Imaging ◽

Radiographic Evidence ◽

Cross Sectional ◽

Meniscal Lesions ◽

Structural Abnormalities

Abstract Background: The prevalence of minute structural abnormalities in early knee osteoarthritis (KOA) and their association with knee symptoms remains unclear. We investigated the prevalence of abnormalities detected by magnetic resonance imaging (MRI) and their relation to knee symptoms in women without radiographic evidence of KOA.Methods: This cross-sectional cohort study in a Japanese population included 261 women without radiographic evidence of KOA, which was defined as a Kellgren‒Lawrence grade < 2. All participants underwent T2-weighted fat-suppressed MRI of their right knee. Structural abnormalities (cartilage damage, bone marrow lesions [BMLs], subchondral cysts, bone attrition, osteophytes, meniscal lesions, and synovitis) were scored according to the Whole-Organ MRI Scoring method. Knee symptoms were evaluated by the Knee injury and Osteoarthritis and Outcome Score (KOOS). Participants were divided into early KOA and non-KOA groups based on early KOA classification criteria. Logistic regression analysis was performed to evaluate the relationship between MRI abnormalities and knee symptoms.Results: Cartilage damage were the most common abnormality (53%), followed by osteophytes (43%), and BMLs (33%). The prevalence of BMLs (47%), meniscal lesions (26%), and synovitis (37%) was higher in early KOA than in non-KOA. On logistic regression analysis, synovitis (odds ratio [OR] = 1.901, P = 0.013) and meniscal lesions (OR = 1.410, P = 0.045) were positively associated with the presence of early KOA.Conclusions: The prevalence of BMLs, meniscal lesions, and synovitis was higher in symptomatic knees. Synovitis was most strongly associated with knee pain and might be a therapeutic target in patients with early KOA.

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Magnetic resonance imaging and biological markers in pituitary adenomas with invasion of the cavernous sinus space

Journal of Neuro-Oncology ◽

10.1007/s11060-004-6150-9 ◽

2005 ◽

Vol 74 (1) ◽

pp. 71-76 ◽

Cited By ~ 43

Author(s):

Li-xiong Pan ◽

Zhong-ping Chen ◽

Yun-sheng Liu ◽

Ji-hong Zhao

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Cavernous Sinus ◽

Biological Markers ◽

Pituitary Adenomas ◽

Resonance Imaging ◽

And Biological Markers

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A Logistic Regression Analysis for Tissue Stiffness Categorization Through Magnetic Resonance Elastography

10.1115/1.0004411v ◽

2021 ◽

Author(s):

Mohammadreza Ramzanpour ◽

Mohammad Hosseini-Farid ◽

Jayse Mclean ◽

Mariusz Ziejewski ◽

Ghodrat Karami

Keyword(s):

Logistic Regression ◽

Regression Analysis ◽

Magnetic Resonance ◽

Logistic Regression Analysis ◽

Magnetic Resonance Elastography ◽

Tissue Stiffness

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Do We Need Intraoperative Magnetic Resonance Imaging in All Endoscopic Endonasal Pituitary Adenoma Surgery Cases? A Retrospective Study

Frontiers in Oncology ◽

10.3389/fonc.2021.733838 ◽

2021 ◽

Vol 11 ◽

Author(s):

Emrah Celtikci ◽

Muammer Melih Sahin ◽

Mustafa Caglar Sahin ◽

Emetullah Cindil ◽

Zuhal Demirtaş ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Pituitary Adenoma ◽

Magnetic Resonance ◽

Cavernous Sinus ◽

Residual Tumor ◽

Correct Prediction ◽

Resonance Imaging ◽

Mri Scan ◽

Endoscopic Endonasal ◽

Grade 3

There are previous reports investigating effectiveness of intraoperative magnetic resonance imaging (IO-MRI) in pituitary adenoma surgery but there is no clear data in the literature recommending when there is no need of intraoperative scan. This retrospective analysis was based on determining which patients does not need any IO-MRI scan following endoscopic endonasal pituitary adenoma surgery. Patients with functional or non-functional pituitary adenomas that were operated via endoscopic endonasal approach (EEA) between June 2017 and May 2019 were enrolled. Patients younger than 18 years old, patients who did not underwent IO-MRI procedure or not operated via EEA were excluded from the study. Hence, this study is designed to clarify if IO-MRI is useful in both functional and non-functional pituitary adenomas, functional adenomas did not split into subgroups. A total of 200 patients treated with pituitary adenoma were included. In Knosp Grade 0 – 2 group, primary surgeon’s opinion and IO-MRI findings were compatible in 150 patients (98.6%). In Knosp Grade 3 – 4 correct prediction were performed in 32 (66.6%) patients. When incorrectly predicted Knosp Grade 3 – 4 patients (n = 16) was analyzed, in 13 patients there were still residual tumor in cavernous sinus and in 3 patients there were no residual tumor. Fisher’s exact test showed there is a statistically significant difference of correct prediction between two different Knosp Grade groups (two-tailed P < 0.0001). Eighteen patients had a residual tumor extending to the suprasellar and parasellar regions which second most common site for residual tumor. Our findings demonstrate that there is no need of IO-MRI scan while operating adenomas limited in the sellae and not invading the cavernous sinus. However, we strongly recommend IO-MRI if there is any suprasellar and parasellar extension and/or cavernous sinus invasion.

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