Cyclocondensation reactions of 5-aminopyrazoles, pyruvic acids and aldehydes. Multicomponent approaches to pyrazolopyridines and related products

Tetrahedron ◽  
2007 ◽  
Vol 63 (5) ◽  
pp. 1229-1242 ◽  
Author(s):  
Valentin A. Chebanov ◽  
Yana I. Sakhno ◽  
Sergey M. Desenko ◽  
Vitaliy N. Chernenko ◽  
Vladimir I. Musatov ◽  
...  
Keyword(s):  
Cyclocondensation Reactions ◽  
Pyruvic Acids

Cyclocondensation Reactions of 5-Aminopyrazoles, Pyruvic Acids and Aldehydes. Multicomponent Approaches to Pyrazolopyridines and Related Products.

ChemInform ◽  
2007 ◽  
Vol 38 (22) ◽  
Author(s):  
Valentin A. Chebanov ◽  
Yana I. Sakhno ◽  
Sergey M. Desenko ◽  
Vitaliy N. Chernenko ◽  
Vladimir I. Musatov ◽  
...  
Keyword(s):  
Cyclocondensation Reactions ◽  
Pyruvic Acids

Regioselective Synthesis of Pyrazolyl-pyrimidine Hybrids of Pharmacological Interest

Synthesis ◽  
2020 ◽  
Vol 52 (16) ◽  
pp. 2347-2356 ◽  
Author(s):  
Nilo Zanatta ◽  
Adriano F. Camargo ◽  
Mário A. Marangoni ◽  
Paulo A. de Moraes ◽  
Pablo A. Nogara ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
Regioselective Synthesis ◽  
Pharmacological Interest ◽  
Cyclocondensation Reactions

The regioselective synthesis of twenty novel [3-substituted 5-hydroxy-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-1-yl][6-aryl-(2-methylthio)pyrimidin-4-yl]methanones from the cyclocondensation reactions of new 6-aryl-2-(methylthio)pyrimidine-4-carbohydrazides with 4-substituted 1,1,1-trifluorobut-3-en-2-ones is reported. Human acetylcholinesterase (HsAChE) and butyrylcholinesterase (HsBChE) inhibition tests were performed on selected products in order to explore the possible pharmacological applications of these compounds. Two compounds showed significant and selective inhibitory activity for BChE.

scholarly journals Cross Photoreaction of Glyoxylic and Pyruvic Acids in Model Aqueous Aerosol

2018 ◽  
Vol 122 (31) ◽  
pp. 6457-6466 ◽  
Author(s):  
Sha-Sha Xia ◽  
Alexis J. Eugene ◽  
Marcelo I. Guzman
Keyword(s):  
Pyruvic Acids

ChemInform Abstract: Enantio- and Diastereoconvergent Cyclocondensation Reactions: Synthesis of Enantiopure cis-Decahydroquinolines.

ChemInform ◽  
2014 ◽  
Vol 45 (18) ◽  
pp. no-no
Author(s):  
Mercedes Amat ◽  
Elena Ghirardi ◽  
Laura Navio ◽  
Rosa Griera ◽  
Nuria Llor ◽  
...  
Keyword(s):  
Cyclocondensation Reactions
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