First total synthesis of modiolide A, based on the whole-cell yeast-catalyzed asymmetric reduction of a propargyl ketone

Tetrahedron ◽  
2007 ◽  
Vol 63 (36) ◽  
pp. 8752-8760 ◽  
Author(s):  
Masaaki Matsuda ◽  
Takahiro Yamazaki ◽  
Ken-ichi Fuhshuku ◽  
Takeshi Sugai
Keyword(s):  
Total Synthesis ◽  
Asymmetric Reduction ◽  
Whole Cell

First Total Synthesis of Modiolide A (I), Based on the Whole-Cell Yeast-Catalyzed Asymmetric Reduction of a Propargyl Ketone.

ChemInform ◽  
2007 ◽  
Vol 38 (52) ◽  
Author(s):  
Masaaki Matsuda ◽  
Takahiro Yamazaki ◽  
Ken-ichi Fuhshuku ◽  
Takeshi Sugai
Keyword(s):  
Total Synthesis ◽  
Asymmetric Reduction ◽  
Whole Cell

Asymmetric reduction of a key intermediate of eslicarbazepine acetate using whole cell biotransformation in a biphasic medium

2012 ◽  
Vol 2 (8) ◽  
pp. 1602 ◽  
Author(s):  
Manpreet Singh ◽  
Sawraj Singh ◽  
Sateesh Deshaboina ◽  
Hare Krishnen ◽  
Richard Lloyd ◽  
...  
Keyword(s):  
Asymmetric Reduction ◽  
Eslicarbazepine Acetate ◽  
Whole Cell ◽  
Whole Cell Biotransformation ◽  
Biphasic Medium

Enzyme identification and development of a whole-cell biotransformation for asymmetric reduction of o-chloroacetophenone

2010 ◽  
Vol 108 (4) ◽  
pp. 797-803 ◽  
Author(s):  
Regina Kratzer ◽  
Matej Pukl ◽  
Sigrid Egger ◽  
Michael Vogl ◽  
Lothar Brecker ◽  
...  
Keyword(s):  
Asymmetric Reduction ◽  
Whole Cell ◽  
Whole Cell Biotransformation

Towards the Total Synthesis of Schisandrene: Stereoselective Synthesis of the Dibenzocyclooctadiene Lignan Core

Synlett ◽  
2018 ◽  
Vol 29 (07) ◽  
pp. 908-911 ◽  
Author(s):  
K. Babu ◽  
Arramshetti Venkanna ◽  
Borra Poornima ◽  
Bandi Siva ◽  
B. Babu
Keyword(s):  
Total Synthesis ◽  
Stereoselective Synthesis ◽  
Asymmetric Reduction ◽  
Cross Coupling ◽  
Membered Ring ◽  
Stille Reaction ◽  
Reaction Sequence ◽  
Ring Closing Metathesis ◽  
Synthetic Strategy ◽  
First Time

A stereoselective synthesis of the dibenzocyclooctadiene ­lignan core of the natural product schisandrene is described. Starting from readily available gallic acid, the synthetic strategy involves Suzuki–Miyaura cross-coupling, Stille reaction, and ring-closing metathesis (RCM) in the reaction sequence. The required asymmetric center at C-7′ was established by an asymmetric reduction of a keto compound using the Corey–Bakshi–Shibata (CBS) catalyst. In our approach, the eight-membered ring was achieved by RCM for the first time.

Asymmetric reduction of ketones via whole cell bioconversions and transfer hydrogenation: complementary approaches

2001 ◽  
Vol 12 (7) ◽  
pp. 1025-1034 ◽  
Author(s):  
Annemarie Hage ◽  
Daniëlle G.I Petra ◽  
Jim A Field ◽  
Dick Schipper ◽  
Joannes B.P.A Wijnberg ◽  
...  
Keyword(s):  
Asymmetric Reduction ◽  
Transfer Hydrogenation ◽  
Whole Cell ◽  
Reduction Of Ketones

An Efficient Stereoselective Total Synthesis of All Stereoisomers of the Antibiotic Thiamphenicol through Ruthenium-Catalyzed Asymmetric Reduction by Dynamic Kinetic Resolution

2015 ◽  
Vol 2015 (27) ◽  
pp. 5949-5958 ◽  
Author(s):  
Marc Perez ◽  
Pierre-Georges Echeverria ◽  
Elsa Martinez-Arripe ◽  
Mehdi Ez Zoubir ◽  
Ridha Touati ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Kinetic Resolution ◽  
Asymmetric Reduction ◽  
Dynamic Kinetic Resolution

Asymmetric Reduction of Cyclic Imines Catalyzed by a Whole-Cell Biocatalyst Containing an (S)-Imine Reductase

ChemCatChem ◽  
2013 ◽  
Vol 5 (12) ◽  
pp. 3505-3508 ◽  
Author(s):  
Friedemann Leipold ◽  
Shahed Hussain ◽  
Diego Ghislieri ◽  
Nicholas J. Turner
Keyword(s):  
Asymmetric Reduction ◽  
Whole Cell ◽  
Whole Cell Biocatalyst

ChemInform Abstract: Asymmetric Reduction of Ketones via Whole Cell Bioconversions and Transfer Hydrogenation: Complementary Approaches.

ChemInform ◽  
2010 ◽  
Vol 32 (36) ◽  
pp. no-no
Author(s):  
Annemarie Hage ◽  
Danielle G. I. Petra ◽  
Jim A. Field ◽  
Dick Schipper ◽  
Joannes B. P. A. Wijnberg ◽  
...  
Keyword(s):  
Asymmetric Reduction ◽  
Transfer Hydrogenation ◽  
Whole Cell ◽  
Reduction Of Ketones
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