Transcriptional regulation of type-2 metabotropic glutamate receptors: an epigenetic path to novel treatments for chronic pain

Metabotropic Glutamate ◽

Novel Treatments

Metabotropic glutamate receptors and the control of chronic pain

Current Opinion in Pharmacology ◽

10.1016/j.coph.2011.10.010 ◽

2012 ◽

Vol 12 (1) ◽

pp. 28-34 ◽

Cited By ~ 61

Author(s):

Santina Chiechio ◽

Ferdinando Nicoletti

Keyword(s):

Chronic Pain ◽

Glutamate Receptors ◽

Experience-dependent plasticity without long-term depression by type 2 metabotropic glutamate receptors in developing visual cortex

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.022618799 ◽

2002 ◽

Vol 99 (2) ◽

pp. 1041-1046 ◽

Cited By ~ 46

Author(s):

J. J. Renger ◽

K. N. Hartman ◽

Y. Tsuchimoto ◽

M. Yokoi ◽

S. Nakanishi ◽

...

Keyword(s):

Visual Cortex ◽

Glutamate Receptors ◽

Long Term Depression ◽

Dependent Plasticity ◽

Targeting type-2 metabotropic glutamate receptors to protect vulnerable hippocampal neurons against ischemic damage

Molecular Brain ◽

10.1186/s13041-015-0158-2 ◽

2015 ◽

Vol 8 (1) ◽

Cited By ~ 14

Author(s):

Marta Motolese ◽

Federica Mastroiacovo ◽

Milena Cannella ◽

Domenico Bucci ◽

Anderson Gaglione ◽

...

Keyword(s):

Glutamate Receptors ◽

Hippocampal Neurons ◽

Ischemic Damage ◽

Modulation of Chronic Pain by Metabotropic Glutamate Receptors

Pharmacological Mechanisms and the Modulation of Pain - Advances in Pharmacology ◽

10.1016/bs.apha.2015.11.001 ◽

2016 ◽

pp. 63-89 ◽

Cited By ~ 24

Author(s):

Santina Chiechio

Keyword(s):

Chronic Pain ◽

Glutamate Receptors ◽

Paradoxical sleep deprivation in rats causes a selective reduction in the expression of type-2 metabotropic glutamate receptors in the hippocampus

Pharmacological Research ◽

10.1016/j.phrs.2016.11.029 ◽

2017 ◽

Vol 117 ◽

pp. 46-53 ◽

Cited By ~ 3

Author(s):

Isabella Panaccione ◽

Luisa Iacovelli ◽

Luigi di Nuzzo ◽

Francesca Nardecchia ◽

Gianluca Mauro ◽

...

Keyword(s):

Sleep Deprivation ◽

Glutamate Receptors ◽

Paradoxical Sleep ◽

Selective Reduction ◽

Paradoxical Sleep Deprivation ◽

Targeting metabotropic glutamate receptors for novel treatments of schizophrenia

Molecular Brain ◽

10.1186/s13041-017-0293-z ◽

2017 ◽

Vol 10 (1) ◽

Cited By ~ 49

Author(s):

James Maksymetz ◽

Sean P. Moran ◽

P. Jeffrey Conn

Keyword(s):

Glutamate Receptors ◽

Metabotropic Glutamate ◽

Novel Treatments

N-Acetyl-Cysteine Causes Analgesia by Reinforcing the Endogenous Activation of Type-2 Metabotropic Glutamate Receptors

Molecular Pain ◽

10.1186/1744-8069-8-77 ◽

2012 ◽

Vol 8 ◽

pp. 1744-8069-8-77 ◽

Cited By ~ 25

Author(s):

Matteo Bernabucci ◽

Serena Notartomaso ◽

Cristina Zappulla ◽

Francesco Fazio ◽

Milena Cannella ◽

...

Keyword(s):

Glutamate Receptors ◽

Metabotropic Glutamate ◽

Acetyl Cysteine

Faculty Opinions recommendation of N-Acetyl-cysteine causes analgesia by reinforcing the endogenous activation of type-2 metabotropic glutamate receptors.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717970799.793469286 ◽

2013 ◽

Author(s):

Andrea Truini

Keyword(s):

Glutamate Receptors ◽

Metabotropic Glutamate ◽

Acetyl Cysteine

Supraspinal Metabotropic Glutamate Receptors: An Endogenous Substrate for Alleviating Chronic Pain and Related Affective Disorders

mGLU Receptors - The Receptors ◽

10.1007/978-3-319-56170-7_2 ◽

2017 ◽

pp. 15-31 ◽

Cited By ~ 1

Author(s):

Francesca Guida ◽

Enza Palazzo ◽

Livio Luongo ◽

Ida Marabese ◽

Vito de Novellis ◽

...

Keyword(s):

Chronic Pain ◽

Glutamate Receptors ◽

Affective Disorders ◽

Metabotropic Glutamate ◽

Endogenous Substrate

Postlesional transcriptional regulation of metabotropic glutamate receptors: implications for plasticity and excitotoxicity

Acta Neuropathologica ◽

10.1007/s004010000339 ◽

2001 ◽

Vol 101 (2) ◽

pp. 79-84 ◽

Cited By ~ 7

Author(s):

Kathy Keyvani ◽

Frank Bosse ◽

Sonja Reinecke ◽

Werner Paulus ◽

Otto W. Witte

Keyword(s):

Transcriptional Regulation ◽

Glutamate Receptors ◽