Hypoxia/reoxygenation exacerbates drug-induced cytotoxicity by opening mitochondrial permeability transition pore: Possible application for toxicity screening

Permeability Transition ◽

Toxicity Screening ◽

Drug Induced ◽

Danhong injection protects cardiomyocytes against hypoxia/reoxygenation- and H2O2-induced injury by inhibiting mitochondrial permeability transition pore opening

Journal of Ethnopharmacology ◽

10.1016/j.jep.2015.08.033 ◽

2015 ◽

Vol 175 ◽

pp. 617-625 ◽

Cited By ~ 23

Author(s):

Zhen-Zhen Duan ◽

Yu-Hong Li ◽

Yan-Yan Li ◽

Guan-Wei Fan ◽

Yan-Xu Chang ◽

...

Keyword(s):

Permeability Transition ◽

Danhong Injection ◽

Pore Opening ◽

Pre‑treatment with a combination of Shenmai and Danshen injection protects cardiomyocytes against hypoxia/reoxygenation‑ and H2O2‑induced injury by inhibiting mitochondrial permeability transition pore opening

Experimental and Therapeutic Medicine ◽

10.3892/etm.2019.7462 ◽

2019 ◽

Cited By ~ 2

Author(s):

Lin Li ◽

Zhengmei Sha ◽

Yanyan Wang ◽

Dongli Yang ◽

Jinghao Li ◽

...

Keyword(s):

Permeability Transition ◽

Danshen Injection ◽

Pore Opening ◽

Pre Treatment ◽

Extracellular Cl−-free-induced cardioprotection against hypoxia/reoxygenation is associated with attenuation of mitochondrial permeability transition pore

Biomedicine & Pharmacotherapy ◽

10.1016/j.biopha.2016.12.048 ◽

2017 ◽

Vol 86 ◽

pp. 637-644 ◽

Cited By ~ 4

Author(s):

Xian-Gui Zhang ◽

Le Zhao ◽

Yi Zhang ◽

Yuan-Yuan Li ◽

Huan Wang ◽

...

Keyword(s):

Permeability Transition ◽

Increased Sensitivity of Mitochondrial Permeability Transition Pore to Ca2+ in the Heart of Spontaneously Hypertensive Rats

International Journal of Physiology and Pathophysiology ◽

10.1615/intjphyspathophys.v4.i3.60 ◽

2013 ◽

Vol 4 (3) ◽

pp. 245-251

Author(s):

Nataliya A. Strutynska ◽

Nataliya A. Dorofeyeva ◽

Galyna L. Vavilova ◽

Vadim F. Sagach

Keyword(s):

Spontaneously Hypertensive Rats ◽

Permeability Transition ◽

Hypertensive Rats ◽

Spontaneously Hypertensive ◽

Increased Sensitivity

The Effect of Treadmill Exercise on Sirtuin-3 Expression and Mitochondrial Permeability Transition Pore in the Aged Rat Brain

Korean Journal of Sport Studies ◽

10.23949/kjpe.2017.05.56.3.45 ◽

2017 ◽

Vol 56 (3) ◽

pp. 601-611

Author(s):

Jung-Hoon Koo ◽

Joon-Yong Cho

Keyword(s):

Rat Brain ◽

Treadmill Exercise ◽

Permeability Transition ◽

Sirtuin 3 ◽

Aged Rat ◽

Mitochondrial Permeability

Faculty Opinions recommendation of Cysteine 203 of cyclophilin D is critical for cyclophilin D activation of the mitochondrial permeability transition pore.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717968331.793468042 ◽

2012 ◽

Author(s):

Heinz Osiewacz

Keyword(s):

Permeability Transition ◽

Cyclophilin D ◽

Mitochondrial Permeability

Faculty Opinions recommendation of Mitochondrial permeability transition pore induction is linked to formation of the complex of ATPase C-subunit, polyhydroxybutyrate and inorganic polyphosphate.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.727082352.793536111 ◽

2017 ◽

Author(s):

Paolo Pinton

Keyword(s):

Permeability Transition ◽

Inorganic Polyphosphate ◽

C Subunit

Faculty Opinions recommendation of Silencing of cardiac mitochondrial NHE1 prevents mitochondrial permeability transition pore opening.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.8705956.9224060 ◽

2011 ◽

Author(s):

Franz Kehl ◽

Christopher Lotz

Keyword(s):

Permeability Transition ◽

Pore Opening

Mitochondrial Permeability Transition Pore Opening Promotes Calcium Alternans and Waves in Ventricular Myocytes

Biophysical Journal ◽

10.1016/j.bpj.2015.11.2337 ◽

2016 ◽

Vol 110 (3) ◽

pp. 433a

Author(s):

Zhen Song ◽

Richard Gordan ◽

James N. Weiss ◽

Lai-Hua Xie ◽

Zhilin Qu

Keyword(s):

Ventricular Myocytes ◽

Permeability Transition ◽

Pore Opening

O-10 Menadione mimicked preconditioning via opening of mitochondrial permeability transition pore (MPTP) but not via M-KATP in isolated rat hearts

Journal of Molecular and Cellular Cardiology ◽

10.1016/s0022-2828(02)90301-9 ◽

2002 ◽

Vol 34 (10) ◽

pp. A19

Author(s):

Masato Tani ◽

Ken Yamamura ◽

Yukako Honma ◽

Susumu Nakazawa ◽

Jie Zhu ◽

...

Keyword(s):

Permeability Transition ◽

Rat Hearts ◽

O 10 ◽

Isolated Rat